Glomular Function

Question 0

Filtration barrier

Answer 0

Fenestrated capillary (glomerular) endothelium
Visceral membrane of the glomerular capsule made of podocytes. 
The interviewing basement membrane composed of the fused basal laminas of the other layers

Question 1

What are renal nerves?

Answer 1

Fibres that arise from lower thoracic and first lumbar nerves.

Mainly sympathetic fibres that regulate renal blood flow by adjusting the diameter of the renal arterioles

Question 2

Filtration bar roles

Answer 2

Stops all cells and platelets
Stops large plasma proteins
Stops medium (not small) proteins

Question 3

Glomerular filtration is

Answer 3

The flow of essentially protein free plasma from the glomerular capillaries into the bowmans capsule

Question 4

Glomerular filtration rate (GFR) is

Answer 4

The total amount of filtrate formed per minute by the kidneys and is dependent upon total SA available for filtration, filtration membrane permeability and net filtration pressure

Question 5

Measuring GFR

Answer 5

C = UV/P

U = the conc (mg/ml) of the substance in the urine
V = the flow rate of urine formation (ml/min)
P = the plasma concentration of the same substance in the plasma (mg/ml)

Question 6

Is GFR is high then renal excretion of substances is high. GFR is controlled via 2 main mechanisms..

Answer 6

Nerves

Hormones (renin-angiotensin system)