Glomerlonephritis

Question 1

Glomerlonephritis?

Answer 1

An immunologically mediated inflammation of the renal glomeruli.

Question 2

Glomerlonephritis renal glomeruli?

Answer 2

Question 3

Glomerlonephritis aetiology?

Answer 3

many different types that lead to inflammation and activation of compliment and coagulation cascades, the immune complexes may form within the glomerulus or be deposited from the circulation.

Question 4

Glomerlonephritis epidemiology?

Answer 4

accounts for 25% of cases of chronic renal failure.

Question 5

Glomerlonephritis symptoms?

Answer 5

haematuria,

subcutaneous oedema,

polyuria or oliguria,

history of recent infection,

symptoms of uraemia or renal failure.

Question 6

Glomerlonephritis signs?

Answer 6

Hypertension,

proteinuria,

haematuria,

renal failure

Question 7

Glomerlonephritis, nephrotic syndrome?

Answer 7

syndrome consists of triad of proteinuria, low serum albumin, oedema. Due to the hypoalbuminaemia, the liver tries to compensate and causes hyperlipidaemia.

Question 8

Glomerlonephritis nephritic syndrome?

Answer 8

consists of triad of hypertension, proteinuria, haematuria. Pores in the podocytes allow protein and red blood cells through.

Question 9

Glomerlonephritis investigations?

Answer 9

FBC, U&Es + creatinine,

LFTs (check albumin),

lipid profile,

complement studies,

antibodies,

urine (for protein and RBCs),

renal tract USS to exclude other pathology.