Globular Proteins

Question 1

What are globular proteins?

Answer 1

-compact, spherical and soluble in water
-form circle shape when folding into tertiary structure
-non polar face in -polar turn on themselves on the outside = soluble in water

Question 2

Haemoglobin - globular protein

Answer 2

-has quaternary structure
-4 polypeptide chains - 2 alpha, 2 beta
-each chain with prosthetic group
-held together with disulphide bonds
-if changes occur = sickle cell anaemia

Question 3

Enzymes - globular protein

Answer 3

-in saliva + tears - catalyses breakdown of molecule in bacterial cell wall
-1 chain that folds to form an active site
-critical to active site where substrate binds

Question 4

Insulin - globular protein

Answer 4

-produced in pancreas - control blood glucose
-2 polypeptide chains
-held together by 3 disulphide bridges
-carry out function by binding to specific receptor molecules