glial cells Flashcards

1
Q

what system are glial cells apart of

A

the nervous system, along with neurons

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2
Q

types of glial cells

A

astrocytes, oligodendrocytes, microglia

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3
Q

neural stem cells

A

guide neurons to their final destination through radial glial cells, which form the path along which neurons move

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4
Q

neural stem cells

A

oligodendrocytes and astrocytes form from these

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5
Q

how do neuronal stem cells work?

A

neurons develop from the stem cells, attach themselves through the radial glial cell, which they can move along to their final destination before detatching and forming neuronal connections

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6
Q

why are radial glial cells important

A

important for development and making sure cells are where they need to be

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7
Q

astrocytes

A

small to medium sized glial cells with lots of extensions

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8
Q

what is the role of astrocytes (3)

A

maintain homeostasis and equilibrium between different substances in the brain, regulate chemical concentration, and contribute to neuronal repair

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9
Q

why is equilibrium between substances in the brain important

A

the concentration of ions and neurotransmitters have to be exactly right for neuronal cells to function properly

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10
Q

how do astrocytes work

A

take up substances from extracellular space if it gets too high or release substances if it gets too low

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11
Q

how do astrocytes contribute to neuronal repair

A

form a glial scar around the area

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12
Q

blood brain barrier

A

protects the brain from being exposed to harmful substances

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13
Q

why are astrocytes important for the blood brain barrier

A

they make the blood brain barrier tighter and more secure, by forming feet which cover blood vessels so its more difficult for substances in the blood to penetrate the vessel into the brain space

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14
Q

oligodendrocytes

A

form myelin sheets around neurons, snake around the neuron axon to form a tight insulation barrier

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15
Q

why are oligodendrocytes important

A

help increase the speed of information along the axon

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16
Q

microglia

A

first line of defence against infections in the brain

17
Q

how are microglia created

A

bone marrow

18
Q

why are microglia used instead of white blood cells

A

the blood brain barrier keeps white blood cells out of the brain

19
Q

how do microglia work

A

change their shape and become ‘activated’, help eat away at harmful substances through active surveillance and phagocytosis

20
Q

phagocytosis

A

cellular process for englufing and eliminating particles, such as dead cells

21
Q

why are microglia important

A

limiting damage inside the brain, stop harmful substances from dying cells affecting other neurons

22
Q

peripheral nervous system glial cells

A

satellite cells, schwann cells