Glaucoma_Test2 Flashcards
Secondary glaucoma represents how many of glaucoma cases?
2/3rds
Angle Open: Sec glauc……
Pigmentary Glaucoma
Exfoliative glaucoma
Steroid induced
Uveitic glaucoma (for the most part)
Angle Open or Closed: Sec glauc………
Early and Late Traumatic
Lens Induced
Inflammatory
Angle closed: Sec glauc………..
Neovascular
Patient profile for pigmentary glaucoma?
Myopic white male. Nice deep chamber Blue Iris midperipheral TID San Polesi Line
When is the only time you can cure Pigmentary glaucoma?
Before the pressure spikes.
You would treat the patient with Iridotomy.
What is the minor problem in pigmentary glaucoma?
Posterior bowing of mid-peripheral iris: reverse pupil block.
Blcokage of TM and elevation of pressure from pgiment
Is there a hereditary component associated with pgimentary glaucoma?
Yes
Chromosome 7
Is pigmentary glaucoma a bilateral condition?
Si.
What is the big problem in pigmentary glaucoma?
Continual digestion of pigment that leads to degeneration of TM
What is Scheie line?
Pigment on the lens equator
What does pigmentary glaucoma look like in black folks?
Rare endothelial pigment
Rare to no TID
Heavy meshwork pigment
These signs are overlooked many times
How to treat Pigmentary glaucoma?
Tx sim to POAG
1.Drops: beta blocker, CAI, adrenergic agonist, PGAs
Pilocarpine = not well tolerated and risk of RD
2. Argon laser trabeculoplasty: Do within the first year=80% chance of success.
3. Trabeculectomy
4. f/u q3-6 mos for IOP check. Big time variation in IOP
Iridotomy and Pigmentary glaucoma?
SO there is no closed angle here but there is
reverse pupil block = increased IOP in A/C forces the iris backwards into apposition with the lens zonules.
Iridotomy allows for the shallowing of the ant chamber and flattening of the iris.
Glacomafleccken?
Necrotic anterior lens capsule
How do you catch exfoliative glacuoma?
1.Via dilating the eyes.
The IOP rises big time due to the pigment that being liberated.
2. Radial pigmentation on anterior surface of the lens
3. Peripupillary TID
MOA of exfoliative glaucoma?
Deposition of abnormal BM on anteiror lens capsule, iris, and in TM. Abnormal material can come from any structure.
Posterior synechiae can form due to stickiness of material.
In which population does exfoliative glaucoma usually occur in?
Northern Europeans
Will lensectomy cure exfoliative glaucoma?
Nope
What is Exfoliative glaucoma associated with?
Central retinal vein occlusion.
There is a systemic association here.
Is exfoliative glaucoma unilateral?
Yes. U will see it in one eye before you see it in both eyes.
Which condition is worse? POAG or Exfoliative glaucoma?
Exfoliative:
More meds needed
More surgery
More likely to progress to visual disability
Trt of pseudoexfoliative glauc?
Treat as POAG
1. Drops: beta, PGA, Ad ag, CAIs
ALT
Trabeculectomy
Which two glaucomas are in the spectrum of the same disease process?
Pigmentary glaucoma
Pseudoexfoliative glaucoma
What are some examples of early traumatic glaucoma?
Hyphema
Inflammation
TM changes
Hours to days
What are some examples of late traumatic glaucoma?
Angle recession
Peripheral anterior synechiae
Weeks to years
What is a hyphema?
A tear in ciliary body (usually longitudinal muscle). Can lead to angle recession(50-90%).
IOP rise related to blood in A/C.
Pupil block secondary to clot
Trt of hyphema?
Bed reest
Atropine BID
Pred forte q1h
Aq supp.
What drugs do we want to avoid in patients with hyphema, an early traumatic glaucoma?
PGAs
Miotics
Aspirin
What follows traumatic hyphema or vitreous hemorrhage?
Ghost cell carcinoma
RBCs lose hemoglobin, can’t bed to get out of TM and gets trapped, CLOGGAGE
How do you treat ghost cell carcinoma?
Paracentisis
What is the etiology of angle recession?
TM scarring/sclerosis.
Look at fellow eye
What is the percentage of angle recession converting to secondary glaucoma?
10-20%
Forever at risk.
Trt of angle recession
Aq supp
Miotics -questionable
PGAs and trabeculectomy work very very well!!!!
ALT/SLT = questionable.
What is the number one cause for unilateral glaucoma?
Unilateral glaucoma
What three glaucomas should u think to be the cause for unilateral glaucoma?
Angle recession