git patho Flashcards

1
Q

mumps involve which organs

A

parotid
testicle(orchitis)
pancreas
meninges

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2
Q

most common tumor of salivary gland

A

pleomorphic adenoma

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3
Q

which nerve affected by malignant tumor of parotid gland

A

facial nerve

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4
Q

which is the 2nd most common type of benign tumor of salivary gland

A

warthin tumor

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5
Q

most common malignant tumor of salivary gland?

A

mucoepidermoid tumor

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6
Q

esophageal web has increased risk for which cancer?

A

squamous cell carcinoma

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7
Q

features of plummer vinson syndrome

A

Fe deficiency anemia
esophageal web
red tongue due to atrophic glossitis

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8
Q

zenker diverticulum arises where?

A

upper esophageal sphincters

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9
Q

reason for mallory weiss syndrome?

A

severe vomiting causing laceration at GE junction

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10
Q

most common cause of death in cirrhosis?

A

esophageal varices rupture due to portal hypertension

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11
Q

painless hematemesis and panful hematemesis seen in which diseases?

A

painful: mallory weiss syndrome
painless: esophageal varices

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12
Q

reason for achalasia

A

damaged ganglion cells in myenteric plexus

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13
Q

bird beak sign seen in which condition?

A

achalasia

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14
Q

how clinically Gerd and achalasia differentiated?

A

by giving proton inhibitors

no response in achalasia

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15
Q

risk factors for gerd?

A
obesity
fat rich diet
caffeine
smoking
alcohol
hiatal hernia
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16
Q

what change seen in barret esophagus

A

epithelium line changes from NKSSE to non ciliated columnar cell with goblet cell

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17
Q

difference between gastroschisis and omphalocele

A

in omphalocele there is persistent herniation and the abdominal content which are protruded are covered in amnion sac and peritoneum while those in gastroschisis are not covered but bare.

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18
Q

when congenital pyloric stenosis is presented?

A

2 weeks after birth

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19
Q

clinical features of pyloric stenosis?

A

olive shaped mass in abdomen
projectile vomiting
visible peristalsis

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20
Q

what is curling ulcer?

A

Curling’s ulcer is an acute gastric erosion resulting as a complication from severe burns. decreased blood supply upset the defense mechanism.

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21
Q

what is Cushing ulcer?

A

increased vagus stimulation due to brain injury which leads to increased acid production

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22
Q

what is stress ulcer

A

Stress ulcers are multiple, superficial erosions which develop after shock, sepsis, and trauma and are often found in patients with chronic medical illness.

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23
Q

which hypersensitivity is involved in autoimmune chronic gastritis?

A

type 4

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24
Q

diagnostic feature of AI chronic gastritis

A

antibodies against parietal cells

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25
what is the most common cause of sialadenitis
sialolithiasis. obstruction due to stone
26
why pleomorphic adenoma has high rate of recurrence?
irregular margins
27
4 symptoms of TE fistula?
vomiting polyhydramnios abdominal distension aspiration
28
esophageal web increases risk for what?
esophageal squamous cell carcinoma
29
what is halitosis and when it is seen?
bad breath | zenker diverticulum
30
how esophageal vein drain into portal vein
through left gastric vein
31
painless hematemesis seen when?
esophageal varices
32
most common cause of death in cirrhosis?
esophageal varice
33
what are the 2 key probs in achalasia?
unable to relax LES | impaired peristalsis
34
where is myenteric plexus present?
between inner circular and outer longitudinal layers of muscularis propria
35
classic disease linked with achalasia
trypanosoma cruzi infection in chagas disease
36
achalasia increases risk for what diseases
autoimmune | esophageal squamous cell carcinoma
37
what type of metaplasia is seen in barret esophagus?
NKSSE changes into nonciliated columnar epithelium with goblet cells
38
does gerd always causes barret esophagus?
no, only 10% of time
39
what are the late complications of gerd?
ullceration with stricture | barret esophagus
40
what are the complication of barret esophagus?
dysplasia | adenocarcinoma
41
pyloric stenosis presents when?
2 weeks after birth | mostly in males
42
3 symptoms and signs of pyloric stenosis?
olive like mass in abdomen projectile vomiting visible peristalsis
43
what is the cause of acute gastritis?
acidic damage to mucosa
44
what is curling cancer
severe burn decreases blood supply to mucosa of stomach which is one of the normal defense mechanism
45
what is cushing ulcer?
increased intracranial pressure causing vagus simulation which releases ach which increase acid production by parietal cells
46
risk factors for acute gastritis
``` severe burn shock(stress ulcer) NSAIDS(decreases PGE2) alcohol consumption cushing and curling ulcer chemotherapy ```
47
chronic autoimmune gastritis targets which area
body and fundus of stomach
48
chronic H.pylori targets which area
antrum of stomach
49
which cells are targeted in chronic AI gastritis and how do you diagnose
parietal cells | autoantibodies against parietal cells and intrinsic factor
50
clinical feature of chronic AI gastritis
atrophy of mucosa achlorhydria G cell hyperplasia megaloblastic anemia
51
complication of chronic gastritis? autoimmune type
gastric adenocarcinoma involving metaplasia of intestinal type
52
what is the most common cause of Vit B1 2 deficiency
chronic gastritis
53
what are the complications of Hpylori gastritis
peptic ulcer disease gastric adenocarcinoma MALT lymphoma
54
2 types of peptic ulcer disease?
1. duodenum (90%) | 2. gastric (10%)
55
reasons of duodenal ulcer?
95% of time due to H pylori | 5% of time ZE syndrome
56
diagnosis of duodenal ulcer?
hypertrophy of brunner gland to compensate for damage
57
most common site of duodenal ulcer?
wall of anterior duodenum
58
complications of post duodenum duodenal ulcer?
acute pancreatitis | gastroduodenal artery bleeding
59
reasons for gastric ulcer?
H pylori (75%) NSAIDS bile reflux
60
location of gastric ulcer?
lesser curvature of antrum
61
duodenal atresia is associated with what disease?
down syndrome
62
double bubble sign and bird beak sign is seen in what probs?
bird beak seen in achalasia | double bubble seen in duodenal atresia
63
what is the most common congenital anomaly of git
meckel diverticulum