GIST Flashcards

1
Q

Qual o órgão mais acometido pelo GIST?

A

Estômago

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2
Q

Qual tipo celular da GIST?

A

Células intersticiais de Cajal

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3
Q

Qual o aspecto macroscópico do GIST?

A

Bem delimitado, nodular

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4
Q

Qual o tratamento padrão do GIST?

A

Excisão do tumor com margens

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5
Q

Se faz linfadenectomia no GIST?

A

Não

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6
Q

Quando é possível conduta conservadora no GIST?

A

Se < 2cm

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7
Q

Em qual situação ressecar tumor com < 2cm?

A

Se lesão irregular, aspecto heterogêneo ou ulcerado

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8
Q

Quando fazer biópsia no GIST?

A

Se invasão ou metástase

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9
Q

Quando realizar imatinibe no GIST?

A

Metástase
Irressecável
Risco de recorrência: > 3cm, >/ 5 mitoses ou recorrente

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10
Q

Quais os marcadores encontrados no GIST?

A

CD 117 e CD 34

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11
Q

Qual proto-oncogene associado ao CD117?

A

Proto-oncogene KIT

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