GIS05 06 Gross Anatomy Of The GI Flashcards
Esophagus
- Muscular tube (~25cm long)
- Conveys food from pharynx to stomach
- behind trachea, heart; adjacent to aorta (danger of penetration)
3 parts:
- Cervical part (skeletal)
- Thoracic part (smooth + skeletal)
- Abdominal part (smooth)
3 constrictions:
- Upper esophageal constriction (level of cricoid cartilage)
- Middle esophageal constrictions (level of aortic arch)
- Lower esophageal constriction (level of diaphragm)
Clinical significance:
- passing instruments through esophagus into stomach
- viewing radiographs in dysphagia patients
Esophageal hiatus
- Opening in ***muscular right crus of diaphragm
- Left of median plane
- Level of ***T10
***Hiatus hernia: Protrusion of stomach into mediastinum through esophageal hiatus
Gastro-esophageal reflux disease (GERD)
- Reflux of stomach content in esophagus
- ***Barrett’s esophagus: esophageal tissue replaced by tissue more similar to intestinal lining (Stratified squamous non-keratinised —> Simple columnar)
Venous drainage of esophagus
Venous plexus in esophageal wall
–> **Portal vein (via gastric veins) / **Azygos vein (via esophageal veins)
Portal hypertension: Esophageal varices / bleeding
***Innervation of esophagus
***Esophageal plexus (+ Peri-arterial plexus: around left gastric artery + inferior phrenic arteries)
Esophageal plexus formed by:
SNS:
- ***Thoracic sympathetic trunk (T2-T4)
- -> Greater splanchnic nerves (distal esophagus)
- -> innervate Thoracic + Abdominal part
PNS:
- formed by ***L/R Vagus nerve
- -> Anterior/Posterior Vagal trunk
- -> Anterior/Posterior Gastric plexus
–> innervate ***Cervical + Thoracic + Abdominal part
Esophageal cancer and lymphatic drainage
Lymphatic drainage:
- Superior:
* **Bronchomediastinal trunks
- -> Internal jugular vein (L/R), Subclavian vein (L/R)
- -> Brachiocephalic vein (L/R) - Inferiorly:
* **Celiac nodes (same as Gastric lymph drainage)
Stomach
- beneath dome of left diaphragm
- adjacent to spleen
- anterior to pancreas
- intraperitoneal
- greater curvature: ***Greater omentum (double fold of peritoneum: 2 layers)
- when contracted: Gastric mucosa –> ***Gastric rugae (longitudinal folds) –> mixing, ↑ SA for digestion
6 parts:
- Cardia (入口)
- Fundus (頂部)
- Body
- Pyloric antrum
- Pyloric canal
- Pylorus (***Circular sphincter muscle)
Functions (food blender, reservoir):
- Enzymatic digestion of food
- Accumulation of ingested food
- Chemically and mechanically prepare food for digestion –> passage into duodenum
Bariatric surgery –> Adjustable gastric band around stomach to control stomach volume
Blood supply of stomach
Celiac trunk —>
- ***L Gastric artery (lesser curvature)
- Common hepatic artery —> **R Gastric artery (lesser curvature) + Gastroduodenal artery —> **R Gastroomental artery (greater curvature)
- Splenic artery —> ***L Gastroomental artery (greater curvature)
***Innervation of stomach
SNS:
- **Greater splanchnic nerve (pre-ganglionic fibre)
- -> Celiac ganglia (post-ganglionic fibre)
- -> Anterior/Posterior Gastric plexus
PNS:
- **L/R Vagus nerve
- -> Anterior/Posterior Vagal trunk
- -> Anterior/Posterior Gastric plexus
Normal physiological afferent pathway (e.g. fullness): ***Vagus
Pain pathway: carried by visceral afferent fibre that accompany sympathetic nerve
Vagotomy
Surgical section of vagus nerve
Reality - Cut off Anterior / Posterior gastric plexus –> no more visceral afferent pain input (leaving the ***Nerve of Latarjet in place to ensure the emptying function of the stomach remains intact)
Small intestine
- Duodenum: smallest segment
- Jejunum
- Ileum (longest)
- -> Ileocecal junction
Duodenum
- smallest segment
- wrap around pancreatic head
- location for most chemical digestion
4 parts:
- Superior / First (L1 level, ***Intraperitoneal)
- Descending / Second (L2, Intra/Extraperitoneal)
- Inferior / Third (L3, Extraperitoneal)
- Ascending / Fourth (L3, Extraperitoneal)
Structure:
- 1st section of superior part: smooth: Ampulla
- Circular folds: valve of Kerckring
- **Minor duodenal papilla (上d): orifice for **Accessory pancreatic duct
- **Major duodenal papilla (落d) (divide foregut and midgut): orifice for **Main pancreatic duct
Duodenal ulcers: Inflammatory erosions of duodenal mucosa --> ulcer (esp anterior ones) perforates duodenal wall --> contents enter peritoneal cavity --> Peritonitis
Ileum and Jejunum
- 6m long together
- No clear demarcation
- Suspended on mesentery (***intraperitoneal)
- Supplied by Jejunal, Ileal arteries (from ***Superior mesenteric artery, ∵ midgut)
- Arteries form loops / arches: Arcades
Jejunum vs Ileum
Jejunum:
- **short arcades (usually 1 row), **long vasa recta
- more circular folds
Ileum:
- **longer arcades (>= 2 rows), **short vasa recta
- less circular folds
- presence of aggregates of lymphoid nodules: ***Peyer’s patches
Ischaemia of intestine
Occlusion of vasa recta by:
- Emboli (clots from elsewhere)
- Thrombus (clots formed locally)
- Atherosclerotic occlusion / plaque
- -> ischaemia of part of intestine