Gibney Lung Histology Flashcards
Cell composition of Respiratory Epithelium:
- Pseudostratified:
- 30% goblet cells
- 30% ciliated cells
- 30% basal cells
- 3-5% DNES cells
- Bowman’s glands found in lamina propria.
Label all + type of tissue:

lung

Does the olfactory epithelium contain goblet cells?
No.
What is this an image of?

respiratory bronchiole
arrow = outpocketting
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respiratory epithelium

What glands are found in the lamina propria of respiratory epithelium?
Bowman’s glands
What is this an image of?

- Ventricular fold of larynx:
- Pseudostratified epithelium
- Core of connective tissue
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larynx

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Respiratory Epithelium
Pseudostratified with cilia and goblet cells

What is this an image of?

- a terminal bronchiole (black) becoming a Respiratory bronchiole (purple)
How can you tell when muscular bronchioles transition to respiratory brochioles?
- Respiratory bronchioles begin when outpockettings occurs.
Key features of muscular bronchioles in comparison to bronchi:
- No cartilage
- Smooth muscle walls
- Clara cells appear
- Goblet cells disappear
Process of emphysema:
- smoking causes macrophage level increase.
- macrophages secrete chemoattractants and proteases to recruit neutrophils.
- neutrophils release elastase.
- elastic fibers in the alveolar walls broken down.
- smoking α1-antitrypsin level decrease.
- elastase levels from neutrophils increase.
- elastic fibers in alveolar wall degraded faster than replaced.
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bronchus

Label:

clara cell
Respiratory Portion of respiratory system function and structures:
- gas exchange
- respiratory Bronchioles
- alveolar ducts and sacs
- alveoli
Structure of Sustentacular cells in olfactory epithelium:
- support cells
- numerous microvilli
What is the black arrow pointing to?

alveolar dust cell
(phagocytic macrophage)
Composition of respiratory epithelium:
- Simple cuboidal epithelium except where thin outpockettings are found (simple squamous epithelium).
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What is this an image of?

cilia in respiratory epithelium
What is this an image of?

- Vocal fold of larynx:
- Stratified squamous epithelium
- Core of skeletal muscle (Vocalis muscle)
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trachea

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What is this an image of?

- Aveolar Ducts (AD) to
- Aveolar Sacs (AS) to
- Aveoli (A)
Location and function of Type I Pneumocytes:
- Lines alveoli
- Involved in gas exchange
- Covers approx 90% of surface area
Structure of Olfactory receptor cells in olfactory epithelium:
- bipolar cells
- long, thin, non-motile cilia
Label all:

blood-air barrier

Function of Bowman’s glands found in lamina propria of olfactory epithelium:
- Secretes a watery, proteinaceous secretion which serves as a solvent for oderferous substances.
What is this an image of?

cilia in respiratory epithelium
Location and function of Type II Pneumocytes:
- lines alveoli
- Secretes surfactant
- Can divide
Label all + type of tissue:

olfactory epithelium

Conducting portion of respiratory system function and structures:
conducts and warms air to lungs
- Nose and Nasal Cavity
- Nasopharynx and pharynx
- Larynx
- Trachea
- Bronchi
- Muscular Bronchioles, located in lungs
Label all + type of tissue:

olfactory epithelium

What tissue is this an image of?

Respiratory Epithelium
Pseudostratified with cilia and goblet cells
Label all + type of tissue:

muscular bronchiole

Two major divisions of the respiratory system:
- conducting portion
- respiratory portion
Components of Blood-Air Barrier (3):
- Type 1 Pneumocytes
- Shared basement membrane
- Endothelium of capillary
Aveoli are lined by:
- Type I Pneumocytes
- Type II Pneumocytes
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wall of trachea
not surrounded by lung tissue

What type of epithelium is this?

olfactory
thick; no goblet cells
What are the blue arrows pointing to?

pulmonary interstitium in the lung
What is this an image of?

blood-air barrier
- red = type I pneumocyte
- blue = shared basement membrane
- black = endothelial cell of capillary
Key features of olfactory epithelium:
- Receptor cells (olfactory neuron)
- Sustentacular cells
- Basal cells
- NO GOBLET CELLS
What type of tissue is this?

trachea
NOT SURROUNDED BY LUNG TISSUE
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What type of epithelium is this?

respiratory
goblet cells present
What is this an image of?

frontal portion of larynx
What is this an image of?

Type II Pneumocyte
Multilamellar vesicles contain Surfactant
Function of clara cells:
- Located in muscular bronchioles
- Secrete surfactant-like substance to reduce surface tension.
- Stem cell
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Cells in Olfactory Epithelium:
- Pseudostratified
- Olfactory receptor cells (bipolar cells)
- Sustentacular cells (support cells)
- Basal cells (stem cells)
- DNES cells
- Bowman’s glands in lamina propria
Epithelium composition of muscular bronchioles:
- low columnar to cuboidal
- CT contains elastic fibers
Label all + tissue type:

Muscular Bronchiole

What is this an image of?

goblet cell in respiratory epithelium