Gibney Lung Histology Flashcards

1
Q

Cell composition of Respiratory Epithelium:

A
  • Pseudostratified:
    • 30% goblet cells
    • 30% ciliated cells
    • 30% basal cells
    • 3-5% DNES cells
    • Bowman’s glands found in lamina propria.
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2
Q

Label all + type of tissue:

A

lung

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3
Q

Does the olfactory epithelium contain goblet cells?

A

No.

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4
Q

What is this an image of?

A

respiratory bronchiole

arrow = outpocketting

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5
Q

Label all + type of tissue:

A

respiratory epithelium

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6
Q

What glands are found in the lamina propria of respiratory epithelium?

A

Bowman’s glands

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7
Q

What is this an image of?

A
  • Ventricular fold of larynx:
    • Pseudostratified epithelium
    • Core of connective tissue
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8
Q

Label all + tissue type:

A

larynx

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9
Q

Label all + type of tissue:

A

Respiratory Epithelium

Pseudostratified with cilia and goblet cells

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10
Q

What is this an image of?

A
  • a terminal bronchiole (black) becoming a Respiratory bronchiole (purple)
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11
Q

How can you tell when muscular bronchioles transition to respiratory brochioles?

A
  • Respiratory bronchioles begin when outpockettings occurs.
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12
Q

Key features of muscular bronchioles in comparison to bronchi:

A
  • No cartilage
  • Smooth muscle walls
  • Clara cells appear
  • Goblet cells disappear
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13
Q

Process of emphysema:

A
  1. smoking causes macrophage level increase.
  2. macrophages secrete chemoattractants and proteases to recruit neutrophils.
  3. neutrophils release elastase.
  4. elastic fibers in the alveolar walls broken down.
  5. smoking α1-antitrypsin level decrease.
  6. elastase levels from neutrophils increase.
  7. elastic fibers in alveolar wall degraded faster than replaced.
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14
Q

Label all + type of tissue:

A

bronchus

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15
Q

Label:

A

clara cell

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16
Q

Respiratory Portion of respiratory system function and structures:

A
  • gas exchange
  • respiratory Bronchioles
  • alveolar ducts and sacs
  • alveoli
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17
Q

Structure of Sustentacular cells in olfactory epithelium:

A
  • support cells
  • numerous microvilli
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18
Q

What is the black arrow pointing to?

A

alveolar dust cell

(phagocytic macrophage)

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19
Q

Composition of respiratory epithelium:

A
  • Simple cuboidal epithelium except where thin outpockettings are found (simple squamous epithelium).
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20
Q

Label all:

A
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21
Q

Label all:

A
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22
Q

What is this an image of?

A

cilia in respiratory epithelium

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23
Q

What is this an image of?

A
  • Vocal fold of larynx:
    • Stratified squamous epithelium
    • Core of skeletal muscle (Vocalis muscle)
24
Q

Label all + type of tissue:

A

trachea

25
Q

Label all:

A
26
Q

What is this an image of?

A
  • Aveolar Ducts (AD) to
  • Aveolar Sacs (AS) to
  • Aveoli (A)
27
Q

Location and function of Type I Pneumocytes:

A
  • Lines alveoli
  • Involved in gas exchange
  • Covers approx 90% of surface area
28
Q

Structure of Olfactory receptor cells in olfactory epithelium:

A
  • bipolar cells
  • long, thin, non-motile cilia
29
Q

Label all:

A

blood-air barrier

30
Q

Function of Bowman’s glands found in lamina propria of olfactory epithelium:

A
  • Secretes a watery, proteinaceous secretion which serves as a solvent for oderferous substances.
31
Q

What is this an image of?

A

cilia in respiratory epithelium

32
Q

Location and function of Type II Pneumocytes:

A
  • lines alveoli
  • Secretes surfactant
  • Can divide
33
Q

Label all + type of tissue:

A

olfactory epithelium

34
Q

Conducting portion of respiratory system function and structures:

A

conducts and warms air to lungs

  1. Nose and Nasal Cavity
  2. Nasopharynx and pharynx
  3. Larynx
  4. Trachea
  5. Bronchi
  6. Muscular Bronchioles, located in lungs
35
Q

Label all + type of tissue:

A

olfactory epithelium

36
Q

What tissue is this an image of?

A

Respiratory Epithelium

Pseudostratified with cilia and goblet cells

37
Q

Label all + type of tissue:

A

muscular bronchiole

38
Q

Two major divisions of the respiratory system:

A
  1. conducting portion
  2. respiratory portion
39
Q

Components of Blood-Air Barrier (3):

A
  1. Type 1 Pneumocytes
  2. Shared basement membrane
  3. Endothelium of capillary
40
Q

Aveoli are lined by:

A
  • Type I Pneumocytes
  • Type II Pneumocytes
41
Q

Label all + type of tissue:

A

wall of trachea

not surrounded by lung tissue

42
Q

What type of epithelium is this?

A

olfactory

thick; no goblet cells

43
Q

What are the blue arrows pointing to?

A

pulmonary interstitium in the lung

44
Q

What is this an image of?

A

blood-air barrier

  • red = type I pneumocyte
  • blue = shared basement membrane
  • black = endothelial cell of capillary
45
Q

Key features of olfactory epithelium:

A
  • Receptor cells (olfactory neuron)
  • Sustentacular cells
  • Basal cells
  • NO GOBLET CELLS
46
Q

What type of tissue is this?

A

trachea

NOT SURROUNDED BY LUNG TISSUE

47
Q

Label all:

A
48
Q

What type of epithelium is this?

A

respiratory

goblet cells present

49
Q

What is this an image of?

A

frontal portion of larynx

50
Q

What is this an image of?

A

Type II Pneumocyte

Multilamellar vesicles contain Surfactant

51
Q

Function of clara cells:

A
  • Located in muscular bronchioles
    • Secrete surfactant-like substance to reduce surface tension.
    • Stem cell
52
Q

Label all + type of tissue:

A
53
Q

Cells in Olfactory Epithelium:

A
  • Pseudostratified
    • Olfactory receptor cells (bipolar cells)
    • Sustentacular cells (support cells)
    • Basal cells (stem cells)
    • DNES cells
    • Bowman’s glands in lamina propria
54
Q

Epithelium composition of muscular bronchioles:

A
  • low columnar to cuboidal
  • CT contains elastic fibers
55
Q

Label all + tissue type:

A

Muscular Bronchiole

56
Q

What is this an image of?

A

goblet cell in respiratory epithelium