GI viruses

Question 1

Rashes, lesions, photophobia, tachycardia

Answer 1

Picornavirus

Question 2

Under 2 years old

Answer 2

Rotavirus

Question 3

Occurs in winter months of temperate climates

Answer 3

Rotavirus

Question 4

More common in older children and adults

Answer 4

Calicivirus

Question 5

Traveler’s diarrhea (non E. coli)

Answer 5

Rotavirus

Question 6

Associated with food or water contamination

Answer 6

Calicivirus

Question 7

3-10 incubation period followed by 10-14 day mild-moderate diarrhea

Answer 7

Adenovirus

Question 8

Uses the CAR receptor and kills epithelial cells

Answer 8

Adenovirus

Question 9

Can use PCR, Latex agglutination or ELISA types 40 and 41

Answer 9

Adenovirus

Question 10

What kills adenovirus

Answer 10

10% chlorine bleach and hand washing

Question 11

Symptoms last 1-3 days, 48 hour incubation

Answer 11

Calicivirus

Question 12

Vomiting more common in children, diarrhea more common in adults

Answer 12

Calicivirus

Question 13

Includes low fever, chills, myalgia and malaise

Answer 13

Calicivirus

Question 14

Infants may have symptoms up to 6 weeks

Answer 14

Calicivirus

Question 15

Leading cause of foodborne disease

Answer 15

Calicivirus

Question 16

Very short term immunity, 2-3 months

Answer 16

Calicivirus

Question 17

Bind to ABO blood groups

Answer 17

Norovirus

Question 18

Lesions in the jejunum

Answer 18

Norovirus

Question 19

1 virion is contagious with very stable fomites

Answer 19

Norovirus

Question 20

Intestinal epithelia is site of infection and remains positive throughout disease progression

Answer 20

Picornavirus

Question 21

spreads to Lymphoid peyer’s patches

Answer 21

Picornavirus

Question 22

Uses inactivated virus (IPV) for prevention

Answer 22

Poliovirus/picornavirus

Question 23

Incubation 2 days, vomiting is first symptom

Answer 23

Rotavirus

Question 24

By age 3, almost everyone has been infected

Answer 24

Rotavirus

Question 25

Initial infection of mature villis tip cells

Answer 25

Rotavirus

Question 26

NSP4 protein

Answer 26

Rotavirus

Question 27

Can be vaccinated for at an early age to mitigate symptoms

Answer 27

Rotavirus

Question 28

Acute liver failure is rare (.5%)

Answer 28

Hep A (Picornavirus)

Question 29

15-50 day incubation

Answer 29

Hep A (picornavirus)

Question 30

Infects endoreticular system and then spreads to liver

Answer 30

Hep A (picornavirus)

Question 31

Can be shed in stool, urine, [saliva and semen]>2 weeks before and after jaundice

Answer 31

Hep A (picornavirus)

Question 32

May lead to cirrhosis or hepatocellular carcinoma

Answer 32

Hep B (hepedna)

Question 33

Positive HBV serology for 4-15 weeks after infection

Answer 33

Hep B (hepedna)

Question 34

HBV surface antigen indicating they are infectious

Answer 34

HBsAg

Question 35

Indicates recovery and immunity from Hep B or vaccination

Answer 35

Anti-HBs

Question 36

Indicates previous or ongoing Hep B infection

Answer 36

Anti-HBc

Question 37

ALT 200-400

Answer 37

Hep B (hepedna)

Question 38

ALT >400

Answer 38

Hep C (flavivirus)

Question 39

Incidence rate peaks in autumn

Answer 39

Hep A (picornavirus)