GI treatments Flashcards
Tx for anal fissures
- 1st line= fluid and fiber
- stool softeners
- protective ointments, sitz baths
- NTG ointment, topical CCB, Botox injection
Triad for chronic anal fissure
- fissure
- sentinel pile
- hypertrophied anal papilla
tx for anal fissures following failure of conservative tx
lateral anal sphicterotomy
symptomatic tx for internal hemorrhoids
- Stool softeners (docusate, psyllium)
- warm sitz bath
- Anesthetic ointments contining lidocain
- Witch hazel (Hamamelis) compresses
tx for bleeding internal hemorrhoids
injection sclerotherapy w/ 5% phenol in vegetable oil
Tx for larger, prolapsing internal hemorrhoids or those that don’t respond to conservative tx
rubber band ligation
Tx for thrombosed external hemorrhoids
excision
which 2 anticholinergic drug can be used as an antispasmodic in IBS
Hyoscyamine or dycyclomine 30-60 min before meals
Tx for large bowel obstruction (4)
NPO
nasogastric suction
IV fluids
Monitoring
Tx of large bowel obstruction if mechanical obstruction is expected
Urgent surgery
What are 2 things you can do to prevent medication induced esophagitis (NSAIDs, bisphosphonates)
- Drinking pills with at least 4 ounces of water
- avoid laying down for at least 30-60 min after ingestion
Tx for eosinophilic esophagitis (2)
- remove foods that incite allergic response
- topical steroids via inhaler
how do you tx corrosive esophagitis
steroid
Tx for HSV esophagitis
Acyclovir
Tx for CMV esophagitis
Ganciclovir
Tx for uncomplicated GERD (lifestyle)? What should be avoided
- elevating head of the bed 15cm (6in)
- avoiding eating w/in 2-3 hrs of bedtime
- avoid stimulants of acid secretion (coffee, alcohol)
- avoid drugs (anticholinergics)
- Foods (fats, chocolates, etc)
- Avoid smoking
drug therapy for GERD
- start w/ a low-dose H2 receptor antagonist (“-tidine”) QD then increasing to BID if needed
- Switch to PPI (“-prazole”) if sxs persist (start low and increase)
tx for at least 8 wks once sxs controlled
What are the 4 H2 receptor antagonists used to tx GERD
Famotidine
Ranitidine
Nizatidine
Cimetidine
What class of meds are used to tx GERD and end w/ “-prazole”
ex: omeprazole, pantoprazole
PPIs
Tx for NSAID induced gastritis
stop NSAIDs, empiric therapy w/ acid suppression 4-8wk of PPI
Tx for H.pylori gastritis
Clarithromycin
Amoxicillin +/- metronidazole
PPI (omeprazole)
What surgical procedure is indicated for refractory GERD
Nissen fundoplication
Tx for cirrhosis (specifically for encephalopathy, ascites and pruritis)
Avoid alcohol, restrict salt, liver transplant
- Encephalopathy: Lactulose + neomycin
- Ascites: Sodium restriction, paracentesis
- Pruritis: Cholestyramine
What 3 meds can be used for hepatic encephalopathy
- Lactulose
- Rifaximin (reduce risk of re-hosp for hep. enceph)
- Flumazenil (lower blood ammonia levels)
Tx of campylobacter jejuni gastroenteritis
usually self limited
can be treated effectively w/ erythromycin
What 3 infectious agents can cause bloody diarrhea
Shigella, salmonella, enteroinvasive e. coli
Tx for shigella gastroenteritis
Trimethoprim sulfamethoxazole
Tx fro C. diff?
Flagyl x10-14d
Oral vanco?
Tx for rectal cancer
wide local surgical excision
radiation w/ chemo for large tumors w/ mets
Tx for colorectal cancer
surgical resection and chemo for nodal involvement
5FU is mainstay of chemo
monitor CEA w/ treatment
treatment for small bowel obstruction
bowel rest
NG tube placement
Surgery as directed by underlying cause
What abx should be given prior to appendectomy
3rd gen cephalosporin
Tx for upper and lower GI bleed (6)
- Endoscopic thermal pole
- Endoscopic clip
- Endoscopic injection
- Angiographic embolization
- Endoscopic intravariceal cyanoacrylate injection
- Band ligation (esophageal varices or hemorrhoids)
In severe illness of salmonellosis what abx can you give
ciprofloxacin
What is a common cause of osteomyelitis in children with sickle cell disease
salmonellis
What lab finding is indicative for spontaneous peritonitis in cirrhosis
ascitic fluid neutrophil count of 300
(Ascites fluid= PMNs >250, WBC >1000, Ph <7.34)
tx for salmonellosis
ceftriaxone
tx for shigellosis
TMP-SMX or ciprofloxacin