GI Tract I Flashcards

1
Q

GI layers

A

Mucosa
Submucosa
Muscularis externa
Serosa or Adventitia

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2
Q

subdivisions of GI mucosa

A

lining eipthelium,
lamina propria,
muscularis mucosae

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3
Q

functions of GI mucosa

A

protection, absorption, secretion

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4
Q

contents of GI mucosal lamina propria

A

blood and lymphatic vessels,
lymphatic tissue,
wandering connective tissue (plasma cells, eosinophils)

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5
Q

where would plasma cells and eosinophils be found in GI tract

A

mucosal lamina propria

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6
Q

function of mucosal muscularis mucosae

A

smooth muscle, forms ridges and valleys for absorption and secretion

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7
Q

layer of GI tract with dense irregular connective tissue, blood vessels, lymphatic vessels, and Meissner’s nerve plexus

A

submucosa

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8
Q

in what organs does the GI submucosa have glands

A

duodenum, esophagus

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9
Q

where is Meissner’s plexus found in the GI tract

A

periphery of the submucosa

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10
Q

function and structure of HI muscularis externa

A
  • smooth muscle: inner circular and outer longitudinal layers
  • contraction = mix and propel intestinal contents
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11
Q

contraction of this GI layer mixes and propels intestinal contents

A

muscularis extrna

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12
Q

where is Auerbach’s plexus found

A

between inner circular and outer longitudinal layers of smooth muscle in GI muscularis externa

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13
Q

serosa

A

simple squamous mesothelium is present

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14
Q

adventitia

A

part of digestive wall is fixed to abdominal or pelvic wall

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15
Q

contents of GI serosa/adventitia

A

connective tissue,
blood and lymphatic vessels,
nerves

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16
Q

on what surface of the tongue are lingual papillae found

A

dorsal

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17
Q

4 types of papillae on tongue

A

filiform,
fungiform,
foliate,
circumvallate

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18
Q

what type of papillae on the tongue lack taste buds, and have a keritinized epithelium?

A

filiform

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19
Q

type of papillae with taste buds on their dorsal surface

A

fungiform

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20
Q

types of papillae with taste buds on their lateral surfaces

A

foliate, circumvallate

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21
Q

what glands are found in the mucosa of the esophagus

A

esophageal cardia glands - secrete mucous

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22
Q

epithelium of esophagus

A

stratified squamous, nonkeritinized

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23
Q

in what layer are connective tissue and esophageal glands proper found

A

submucosa

24
Q

secrete slightly acidic mucous which facilitates food transport and protects epithelium

A

esophageal glands proper

25
Q

divisions of esophageal muscularis mucosa

A

upper 1/3 = skeletal muscle,
middle 1/3 = skeletal and smooth,
lower 1/3 = smooth

26
Q

where are adventitia and serosa in esophagus

A

adventitia above diaphragm,

serosa below disphragm

27
Q

(upper/lower) esophageal sphincter is made of circular skeletal muscle fibers under voluntary and reflexive control

A

upper

28
Q

(upper/lower) esophageal sphincter is physiological sphincter of thickened circular smooth muscle fibers (not well defined anatomically)

A

lower

29
Q

stomach functions as (endocrine/exocrine) gland

A

both

30
Q

where is chyme formed

A

stomach

31
Q

initiates protein digestion in stomach

A

pepsin

32
Q

digests triglycerides in stomach

A

gastric lipase

33
Q

temporary longitudinal folds of mucosa and submucosa; disappear when stomach is full

A

rugae

34
Q

4 gross regions of stomach

A

cardia,
fundus,
body,
pylorus

35
Q

3 histological regions of stomach

A

cardia,
fundus/body,
pylorus

36
Q

layer of stomach containing simple columnar surface mucous cells, gastric pits, mucosal glands, lamina propria, and muscularis mucosae

A

mucosa

37
Q

stomach mucosal glands empty into

A

gastric pits

38
Q

short, coiled glands with short pits; produce mucous; some produce HCL and lysozyme

A

cardiac glands

39
Q

long straight glands with medium pits

A

gastric/fundic glands

40
Q

4 major cell types in gastric/fundic glands

A

mucous neck cells,
parietal (oxyntic),
chief,
enteroendocrine

41
Q

short, slightly coiled glands with medium pits

A

pyloric glands

42
Q

cell types preset in pyloric glands

A

mucous,
parietal,
enteroendocrine (but can’t see them in histology)

43
Q

submucosa has fold in the (small intestine/stomach)

A

SI

44
Q

what is special about the muscularis externa of the stomach

A

extra inner layer of oblique smooth muscle layer

45
Q

secrete bicarbonate-rich alkaline mucous in stomach

A

surface mucous cells

46
Q

secrete a soluble mucous, occur in small groups or singly between parietal cells in the neck of gastric glands

A

mucous neck cells

47
Q

secrete HCl (from intracellular canaliculus) and intrinsic factor, eosinophilic

A

pareital/oxyntic cells

48
Q

intracellular canaliculus of pareital/oxyntic cells

A

secretes HCl

49
Q

does the stomach have a serosa

A

yes

50
Q

glycoprotein required for vitamin B12 absorption into the ileum

A

intrinsic factor

51
Q

synthesize pepsinogens and gastric lipases in the stomach

A

chief cells

52
Q

where are chief cells found

A

basal half of gastric glands

53
Q

produce gastrin, somatostatin, and ghrelin in the stomach

A

enteroendocrine cells

54
Q

enteroendocrine products (gastrin, somatostatin, ghrelin) act in (paracrine/endocrine) signaling

A

both

55
Q

found in isthmus and neck of mucosal glands in stomach; move up to replace surface mucous cells, move down to replace glandular cells

A

stem cells