GI system: midgut and hindgut Flashcards
superior mesenteric artery syndrome
-cause
superior mesenteric artery crosses the third part of the duodenum anteriorly
- if the duodenum is compressed by a SMA aneurysm it can cause obstruction of the duodenum.
- additionally, can block left renal vein
superior mesenteric artery syndrome
-clinical
- causes bilious vomiting in newborns (and adults?) which is curdled milk mixed with bile so it is greenish
- SMA may also compress left renal vein (nutcracker syndrome)
- may be relieved by patient leaning forward when eating
congenital pyloric stenosis
-cause
-thickening of the smooth muscle of the pyloric sphincter.
congenital pyloric stenosis
-clinical
- non-bilious, projectile vomiting (because obstruction proximal to bile duct)
- abdominal pain
- failure to gain weight
- dehydration
annular pancreas
- what is it?
- problem
- the ventral pancreas may consist of two lobes
- if the lobes migrate around the duodenum in opposite directions to fuse with the dorsal bud, an annular pancreas is formed
- problem: forms ring around the duodenum which can cause an obstruction
annular pancreas
-symptoms and signs in infants
- feeding intolerance
- bilious vomiting (curdled milk mixed with bile (greenish))
- —>therefore constriction usually occurs after sphincter of oddi
- abdominal distension
annular pancreas
-symptoms and signs in adults
- abdominal pain, nausea, vomiting
- upper GI bleeding (from stomach ulceration)
- acute or chronic pancreatitis
abnormalities of midgut rotation
-nonrotation
nonrotation:
- s.i. remains on the right side of the body
- ascending colon in the middle
- descending colon on the left
abnormalities of midgut rotation
-mixed rotation and volvulus
mixed rotation and volvulus:
- accomplishes initial 90 degree rotation (counterclockwise; viewed ventrally)
- but second rotation of 180 degrees is in the opposite direction (clockwise)
- abnormal position of s.i. relative to L.I.
abnormalities of midgut rotation
-subhepatic cecum and appendix
subhepatic cecum and appendix
- if have over-rotation of midgut during retraction (more than 180 degrees counterclockwise)
- results in cecum and appendix being abnormally placed in the upper right quadrant (instead of LRQ)
- in this case appendicitis can mimic biliary pain and present in the RUQ
meckel’s diverticulum
-what?
-failure of vitelline duct (yolk stalk) to completely regress once midgut loop retracts into abdomen
meckel’s diverticulum
-what can it cause?
omphalomesenteric cyst (omphalos means umbilicus) -the fluid in the cyst can become inflamed and result in pain around the umbilicus (mimicking pain of appendicitis)
omphalomesenteric ligament (fibrous band)
- connects ileum to anterior abdominal wall
- can cause pain as well
meckel’s diverticulum
-“syndrome of 2’s”
- 2% of population
- 2” long
- 2 feet proximal to ICJ
- 2 types of mucosa (gastric and intestinal)
- 2X more common in males
- 2% are asymptomatic
McBurney’s Point
- location of the appendix
- 1/3 of the distance from ASIS to umbilicus (on right side)
appendicitis
- definition
- cause
- obstruction of appendiceal lumen leads to inflammation and/or rupture
- cause of obstruction many times is a calcified appendicolith (old piece of stool)