GI Oncology

Question 1

Best treatment option for lipomas?

Answer 1

surgical removal

Question 2

Tests for staging oral melanoma?

Answer 2

FNA of lymph nodes (regardless of size)

Thoracic radiographs

Question 3

Best 2 options for treatment of oral neoplasms?

Answer 3

Surgical excision

Radiation therapy

Question 4

What two factors impact survival time for oral neoplasms the most?

Answer 4

size (affects ability for it to be removed) and metastasis

Question 5

Overall survival time for oral neoplasms?

Answer 5

~1 year (up to 2 years if small)

Question 6

Most important:

1) benign oral tumors
2) malignant oral tumors

Answer 6

1) epulides/ameloblastoma

2) melanoma (also SCC, fibrosarc, and osteosarc)

Question 7

Two treatment options for acanthomatous tumors (epulides)?

Answer 7

Surgery– <5% recurrence with good margins

Radiation (better control with smaller tumors)

Question 8

When would you choose conservative vs. aggressive surgical excision for AGASACA

Answer 8

aggressive if small & no mets

conservative if larger mass and risk for fecal incontinence

Question 9

MST for AGASACA if it’s a small mass with no mets, no hypercalcemia, and it’s able to be excised?

Answer 9

~1.5 years

Question 10

MST for AGASACA if negative prognositc factors are present

Answer 10

~7months

Question 11

How is nodular hyperplasia of the liver treated?

Prognosis?

Answer 11

Don’t treat (not a problem)
maybe give liver support (i.e Denamarin)

Good

Question 12

Treatment options for hepatocellular carcinoma:

1) diffuse form
2) massive form

Answer 12

1) maybe chemo but poor prognosis

2) lobectomy can add years even with incomplete margins

Question 13

the #1 malignant oral neoplasm in cats?

Answer 13

Squamous cell carcinoma (ulcerative)

Question 14

Feline oral SCC is not typically responsive to which type of treatment?

Answer 14

chemotherapy

surgery with or without radiation is best

Question 15

Most commonly diagnosed lymphoma in cats

Answer 15

GI lymphoma (small intestinal, small cell, diffuse lymphoma)

Question 16

Best option for diagnosis of feline GI lymphoma?

Answer 16

exploratory laparotomy with biopsy (endoscopy alone won’t let you reach middle of the bowel)

Question 17

Treatment for feline small cell GI lymphoma is based on?

Answer 17

Grade

High grade=multi-agent protocols

Question 18

Prognosis (MST) for GI lymphoma if:

1) low grade
2) high grade
3) non-responsive to tx

Answer 18

1) ~1year
2) <1 year
3) weeks

Question 19

Other differentials for a mid-abdominal mass in a cat?

Answer 19

GI lymphoma
IBD
Hyperthyroid
Chronic renal failure
Diabetes mellitus

Question 20

Most common gastric neoplasm in dogs?

Answer 20

adenocarcinoma

Question 21

Which method of diagnosis is not preferred for gastric neoplasms?

Answer 21

Endoscopy…can only take a superficial biopsy which won’t include the tumor cells

Question 22

Which gastric neoplasm may be responsive to treatment with tyrosine kinase inhibitors

Answer 22

GIST (stromal tumor)

Question 23

MST of gastric adenocarcinomas and mast cell tumors?

Answer 23

2 months (ACA)
<6 months (MCT)