GI Motility Flashcards

0
Q

peristalsis process

A
food in one region
relaxation of anal region
contraction of region with food
food propelled on (moves to area of lower pressure)
usu travels some distance along gut
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1
Q

peristalsis definition

A

propulsive motility of the gut, move food or chyme from one place to another
requres NO

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2
Q

mixing motion definition

A

mix secretions with food. not as neatly coordinated. localized contraction, no relaxation

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3
Q

mixing motions - process

A

presence of chemicals and food
contraction of region
chyme move to either side
with relaxation, chyme is mixed.

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4
Q

Mouth - mixing

A

mastication

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5
Q

mouth - propulsion

A

swallowing

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6
Q

mastication

A

chewing. unclear neural origin, not required for complete digestion

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7
Q

Swallowing - Stage 1

A

Buccal phase - coluntary

under voluntary control. tongue rolls food back to entrance of pharynx. tongue along roof of mouth from front to back

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8
Q

Swallowing - Stage 2

A

Pharyngeal phase
bolus of food stimulates afferents, synapse in NTS
controlled at reflex level. can take all sensory information and produce these actions
close nasopharynx, create channel for bolos
block trachea

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9
Q

Strokes and swallowing

A

strokes that damage NTS, have a patient with stroke, make sure they can swallow.

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10
Q

cough produced when swallowing wrong

A

produced by larynx= protective

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11
Q

Swallowing - Stage 3

A

Esophageal phase
presence of bolus in esophagus initiates peristalsis. food enters stomach mostly through gravity. peristalsis is clean up
primary peristaliss initiated by swallow, second to clean up debris

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12
Q

Motility of Stomach

A

peristalsis

under some conditions known as pyloric pump

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13
Q

Mixing in stomach

A

retropulsion (variant of peristalsis)

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14
Q

Peristalsis in Stomach

A

peristatltic waves travel down stomach and food moves relatively slowly.
pyloric pressure high, only liquid gets through pyloric valve.

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15
Q

Retropulsion in the stomach

A

peristaltic wave travels down stomach, peristaltic wave travels faster than chyme. most chime cant leave, turns back

16
Q

Pyloric pump

A

stronger waves of peristalsis force chyme through pyloric sphincter,

17
Q

Factors increasing Gastric emptying

A

“food here, get out”
comes from stomach
1. Stretch of gastric wall, vagal and myenteric reflex
2. Gastrin (increases production of gastric acid and motility)

18
Q

Factors decreasing gastric emptying

A

arise from duodenum “wait I’m not ready”
make sure stomach doesnt dump food into SI too fast

  1. enterogastric reflex. distension, acid osmolarity proteins in duodenum, –>decrease gastric motility, increase pyloric tone
  2. Hormones - CCKPZ, Secretin –> increase mixing, decrease emptying
19
Q

Small Intestine Mixing

A

Segmentation

20
Q

Small intestine propulsion

A

peristalsis, with major purpose to distribute chyme for absorption

21
Q

SI Segmentation

A

Mixing, may occur in groups, singly. requires background excitation from myenteric plexus

22
Q

SI peristalsis

A

Frequency varies in different regions. faster in duodenum than ileum.
functions= move chyme to colon, spread chyme evenly.
travels about 5 cm before dying out

23
Q

Neural Control of SI peristalsis

A

gastro enteric reflex,

local and CNS effects

24
Q

Hormonal control of SI in peristalsis

A

Increase motility= gastrin, CCKPZ, insulin
decrrreased motilty= secretin and glucagon (released when acid enters duodenum. need to miz acid with pancreatic bicarb. dont want to push food past sphincter of oddi)

25
Q

Peristaltic Rush

A

irritation in SI
increase peristaltic event
clears SI of irritenat = diarrhea

26
Q

Migrating Motor Complex

A

during fasting, longer you go between meals, stronger these get
matches motilin
starts in stomach, of moderate strenght,
appears to move secretions through intestine. prevents enzymes from acting on damaging mucosa

27
Q

Ileocecal valve

A

prevents bacflow, LI has different bacteria in ith that cause problems when there is backflow

28
Q

Ileocecal sphincter

A

thickening of circular m. control entrance of chyme. normally mildly contracted

29
Q

relaxation of ileocecal sphincter

A
gastric reflex (food in stomach causes ileum to relax, including sphincter)
gastrin
30
Q

Contraction of ileocecal sphincter

A

irritation

distention of the cecum (arises from the colon)

31
Q

Mixing of colon

A

haustrations

32
Q

propulsion of colon

A

mass movement

33
Q

Haustrations

A

like sementation. strong contractions bc fecal material is becoming solid
mixing, triggered by chyme
near complete occlusion of lumen
absorb H2O,
mix HCO3 to counter acids secreted by bacteria

34
Q

Mass Movement

A
propulsive motion. travels more than 20 cm
repeats every 10-30 min until defacation
initiatied by 
gastrocolic reflex
duodenalcolic reflex
parasympathetic
35
Q

Defacation - part 1

A

local reflex.
distension. not strong, not enough to expel fecal matter
sensory motor enteric nervous system.

36
Q

Defacation part 2

A
parasympathetic
distension
receptor in gut
stronger
part 1 and 2 are strong enough for expulsion if EAS is relaxed.
37
Q

Defacation part 3

A

voluntary muscle to relax the EAS