GI Motility Flashcards

0
Q

peristalsis process

A
food in one region
relaxation of anal region
contraction of region with food
food propelled on (moves to area of lower pressure)
usu travels some distance along gut
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1
Q

peristalsis definition

A

propulsive motility of the gut, move food or chyme from one place to another
requres NO

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2
Q

mixing motion definition

A

mix secretions with food. not as neatly coordinated. localized contraction, no relaxation

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3
Q

mixing motions - process

A

presence of chemicals and food
contraction of region
chyme move to either side
with relaxation, chyme is mixed.

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4
Q

Mouth - mixing

A

mastication

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5
Q

mouth - propulsion

A

swallowing

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6
Q

mastication

A

chewing. unclear neural origin, not required for complete digestion

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7
Q

Swallowing - Stage 1

A

Buccal phase - coluntary

under voluntary control. tongue rolls food back to entrance of pharynx. tongue along roof of mouth from front to back

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8
Q

Swallowing - Stage 2

A

Pharyngeal phase
bolus of food stimulates afferents, synapse in NTS
controlled at reflex level. can take all sensory information and produce these actions
close nasopharynx, create channel for bolos
block trachea

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9
Q

Strokes and swallowing

A

strokes that damage NTS, have a patient with stroke, make sure they can swallow.

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10
Q

cough produced when swallowing wrong

A

produced by larynx= protective

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11
Q

Swallowing - Stage 3

A

Esophageal phase
presence of bolus in esophagus initiates peristalsis. food enters stomach mostly through gravity. peristalsis is clean up
primary peristaliss initiated by swallow, second to clean up debris

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12
Q

Motility of Stomach

A

peristalsis

under some conditions known as pyloric pump

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13
Q

Mixing in stomach

A

retropulsion (variant of peristalsis)

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14
Q

Peristalsis in Stomach

A

peristatltic waves travel down stomach and food moves relatively slowly.
pyloric pressure high, only liquid gets through pyloric valve.

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15
Q

Retropulsion in the stomach

A

peristaltic wave travels down stomach, peristaltic wave travels faster than chyme. most chime cant leave, turns back

16
Q

Pyloric pump

A

stronger waves of peristalsis force chyme through pyloric sphincter,

17
Q

Factors increasing Gastric emptying

A

“food here, get out”
comes from stomach
1. Stretch of gastric wall, vagal and myenteric reflex
2. Gastrin (increases production of gastric acid and motility)

18
Q

Factors decreasing gastric emptying

A

arise from duodenum “wait I’m not ready”
make sure stomach doesnt dump food into SI too fast

  1. enterogastric reflex. distension, acid osmolarity proteins in duodenum, –>decrease gastric motility, increase pyloric tone
  2. Hormones - CCKPZ, Secretin –> increase mixing, decrease emptying
19
Q

Small Intestine Mixing

A

Segmentation

20
Q

Small intestine propulsion

A

peristalsis, with major purpose to distribute chyme for absorption

21
Q

SI Segmentation

A

Mixing, may occur in groups, singly. requires background excitation from myenteric plexus

22
Q

SI peristalsis

A

Frequency varies in different regions. faster in duodenum than ileum.
functions= move chyme to colon, spread chyme evenly.
travels about 5 cm before dying out

23
Q

Neural Control of SI peristalsis

A

gastro enteric reflex,

local and CNS effects

24
Hormonal control of SI in peristalsis
Increase motility= gastrin, CCKPZ, insulin decrrreased motilty= secretin and glucagon (released when acid enters duodenum. need to miz acid with pancreatic bicarb. dont want to push food past sphincter of oddi)
25
Peristaltic Rush
irritation in SI increase peristaltic event clears SI of irritenat = diarrhea
26
Migrating Motor Complex
during fasting, longer you go between meals, stronger these get matches motilin starts in stomach, of moderate strenght, appears to move secretions through intestine. prevents enzymes from acting on damaging mucosa
27
Ileocecal valve
prevents bacflow, LI has different bacteria in ith that cause problems when there is backflow
28
Ileocecal sphincter
thickening of circular m. control entrance of chyme. normally mildly contracted
29
relaxation of ileocecal sphincter
``` gastric reflex (food in stomach causes ileum to relax, including sphincter) gastrin ```
30
Contraction of ileocecal sphincter
irritation | distention of the cecum (arises from the colon)
31
Mixing of colon
haustrations
32
propulsion of colon
mass movement
33
Haustrations
like sementation. strong contractions bc fecal material is becoming solid mixing, triggered by chyme near complete occlusion of lumen absorb H2O, mix HCO3 to counter acids secreted by bacteria
34
Mass Movement
``` propulsive motion. travels more than 20 cm repeats every 10-30 min until defacation initiatied by gastrocolic reflex duodenalcolic reflex parasympathetic ```
35
Defacation - part 1
local reflex. distension. not strong, not enough to expel fecal matter sensory motor enteric nervous system.
36
Defacation part 2
``` parasympathetic distension receptor in gut stronger part 1 and 2 are strong enough for expulsion if EAS is relaxed. ```
37
Defacation part 3
voluntary muscle to relax the EAS