G.I. Module 5 Flashcards
Drug class: Action: Neutralize & Decrease Acidity
Antacids
Drug class: Indication: Heartburn and Acid Ingestion Sour Stomach GERD Peptic Ulcer Disease Zollinger Ellison Syndrome Hyperphosphatemia Calcium / Magnesium Deficiency
Antacids
Increased Magnesium can lead to, is contraindicated with (2)
Diarrhea toxicity, Dehydration - dont use in Renal Failure, alcoholics
Increased Aluminum can lead to, used in
Constipation, Dehydration - used for Renal Failure
Increased Calcium can lead to (3)
Bloating, Dehydration, Systemic Alkalosis
Increased Sodium Bicarbonate can lead to (2)
Systemic Alkalosis, Rebound Acidity
What drug class can we use to regulate pH activity
Antacid, preferably 3-4
Frequency of Antacids (3)
12 hours after meals and at the hour of sleep
Has 3 hour duration
Not to exceed 2 week time period
When we have acutely ill patients we must maintain a pH of
7
When using antacids, stool may be _____ in color
chalky
When using enteric meds after antacids what is one thing we must expect
Drug may be broken down sooner than its supposed to because of pH change
Antihistamines block which beta receptor site
H1 beta receptor site
Drug class: Action: Block H2 receptor site on parietal cells decreasing the volume and pH of gastric acid
Antisecretory
Antisecretory meds generally have a
longer duration
Drug class: Indication: Hypersecretory states PUD GERD Zollinger Ellison Decrease amount of HCL being produced
Antisecretory
Frequency of Antisecretory (2)
Short term (4-8 weeks) Prophylactic use (Hour of sleep 10pm)
Side effects of Anti Secretory
Dizziness Headache Disorientation Hallucination Depression Cardiac arrhythmia Decreased bonemarrow MALE BREASTS (Gynecomastia)
Gynecomastia is
Male breasts
What should we monitor for people taking Anti secretory (3)
EKG
Apical pulse
RBC, WBC, Thrombos, CBC
What are some contraindications of Anti secretory meds (3)
Children under 16
Lactating women
Chronic Liver/Kidney disease
Anti secretory meds can alter the results of (2)
allergy test
Gastric acid testing
Nursing implications for giving Anti secretory meds (3)
Give with food except for Nizatidine
Bowel Plan
asses for mood changes
Drug class: Action: Forms a complex that adheres to the ulcer crater, protecting it from irritation
Cytoprotective
Avg dose for Cytoprotective
1g 4x a day
Cytoprotective drugs need an ____________ to be absorbed
acidic environment
Cytoprotective drugs are more effective when
stomach is empty
Because Cytoprotective meds can cause constipation patient should be on
Bowel plan
Best time to take cytoprotective meds are
before meals, or at hour of sleep
If patient is taking a cytoprotective med and an antacid, we should instruct them to
Take antacid 1/2 hour before of 1/2 hour after
Drug class: Action: Reduce gastric acid secretion and protect the mucosal surface of the stomach
Prostaglandins
Drug class: Indication: Prevent gastric ulcer resulting from the use of ASA and NSAIDS
Prostaglandins
Side effects of Prostaglandins include
Abdominal pain
diarrhea
Increased uterine contraction and vaginal bleeding
Before we give our patients a prostaglandins we should make sure of
negative pregnancy
Drug class: Action: Suppress gastric acid secretion by blocking the final step in production of HCI. Acts by binding with Potassium, Adenosine triphosphate and hydrogen in the stomach
Proton Pump Inhibitors
Drug class: Indication: PUD GERD Zollinger - Ellison Syndrome Helibacter Pylori
Proton Pump Inhibitors
Proton Pump Inhibitors are mainly used for
hyper acidic conditions
The two anti secretory drugs classes are
H2 blockers and Proton pump inhibitors
It is recommended to take Proton Pump Inhibitors on a
empty stomach or before meals
Side effects of Proton Pump Inhibitors
Gastric Toxicity
Hypersensitivity
In patients with Helicobacter Pylori there Helidac pack consists of (3)
Bismuth
Tetracycline
Metronidazole
Drug class: Action: Breakdown fats, starches, and protein
Digestants
Drug class: Indication: Replacement in pancreatic enzyme deficiency
Digestants
Digestants should be taken …. because…
with meals because it helps break down food that there eating
Side effects of Digestants are (3)
N+V
Diarrhea
Hyperuricemia
Before administering Digestants we should check for
allergy to pork
Drug class: Action: Induce vomiting
Emetic
Drug class: Action: Attracts substances to its surface and prevent their absorption in the GI tract
Absorbent / Activated charcoal
Drug class: Indication: Ingestion of poison or drug overdose
Absorbent / Activated charcoal
Side effect of Absorbents / Activated Charcoal
Black stools
Absorbents can be given …. and are usually given with …..
oral or NG
Water or fruit juice
Drug: Action: Defoaming agent that breaks up gas bubbles
Simethicone (Mylicon)
Drug: Indication: Post partum gas bubbles
Simethicone (Mylicon)
Drug class: Action: Suppress the vomiting center in the medulla
Antiemetics
Drug class: Indication: N+V, PONV, vertigo motion sickness, hiccoughs
Antiemetics
Drug class: Action: Blocks dopamine receptor site in CTZ
Dopamine Antagonist
PONV stands for
Post op N+V
Drug class: Indication: Short term for N+V related to anticancer drugs
Dopamine Antagonist
Drug class: Action: Block pathway to the CTZ to decrease vomiting (2)
Antihistamine / Anticholinergic
Drug class: Indication: Choice for motion sickness, vertigo, pregnancy (2)
Antihistamine
Scopolamine is administered
behind the ear
Drug class: Action: Marijuana derivatives
Cannabinoids
Drug class: Indication: N+V associated with anticancer drugs , used to stimulate appetite
Cannaboids
Side effects for Cannaboids
Mental depression, clouding, lack of concentration, addiction
Drug class: Action: Block the 5-HT3
Serotonin Antagonist
Drug class: Indication: N+V associated with anticancer drugs, PONV
Serotonin Antagonist
Drug class: Action: Gastric content in small intestines faster by increasing upper GI motility
Gastric Stimulant
Do not administer Gastric Stimulants in people with
intestinal obstruction
Drug class: Action: Reduce anxiety and used as a adjuncts
Benzodiazepine
Drug class: Indication: Reduce anxiety, induce amnesia
Benzodiazepine
Drug class: Indication: Adjuvant for N+V associated with use of anticancer drugs
Glucocorticoids
Drug class: Action: Promote evacuation of the bowel
Laxatives
Drug class: Indication:
Constipation
To prepare for procedure
Laxatives
Drug class: Action: Increase bulk in the stool to stimulate peristalsis
Bulk laxative
Drug class: Action: Oils that soften the stools and allow easy passage of the fecal mass
Lubricant / Emollient
Drug class: Indication: Prevent chronic constipation
Lubricant / Emollient
Drug class: Action: When in contact with the bowel cause irritation of the bowel to stimulate peristalsis. They absorbed into the systemic circulation and also draw water into the bowel which result in a watery stool
Stimulant/Irritant/Contact
Drug class: Indication: Intermittently to prepare the patient for diagnostic test in the GI tract like barium GI
Stimulant/Irritant/Contact
Drug class: Action: Hypertonic solution that concentrate in the bowel and attracts water from the tissue into the bowels by a process of osmosis
Saline
Drug class: Indication: Mainly used as bowel prop prior to surgery of diagnostic test in the GI system such as sigmoidoscopy colonoscopy
Saline
Used to cleanse the bowel by fluid overload that is osmotically balanced
Bowel Evacuant
Drug class: Action: Draws water into the stools to soften the stools to make a passage easier
Fecal Softener
Drug class: Indication: To PREVENT constipation and straining in patients
Fecal Softener
Drug class: Action: decreased peristalsis
Antidiarrheal Agents
Drug class: Action: decreased peristalsis
spasm
GI motility
Opiates
Drug class: Action: Act through the parasympathetic nervous system
Antispasmodic / Spasmolytics / Belladonna Alkaloids
Generic Cimetidine
Tagamet
Generic Famotidine
Pepcid
Generic Prochlorperazine
Compazine
Generic Hydroxyzine
Atarax-Vistaril
Generic Meclizine
Antivert
Generic Metoclopramide
Reglan
Generic Psyllium
Metamucil
Generic Bisacodyl
Dulcolax
Generic Docusate sodium
Colace
Generic Diphenoxylate HCL
Imodium
Generic Lactulose
Cephulac
Generic Sucralfate
Carafate
Generic Omeprazole
Prilosec
Generic Ondansetron
Zofran
Trade Tagamet
histamine H2-receptor antagonist
Trade Pepcid
histamine H2-receptor antagonist.
Trade Prilosec
Proton Pump Inhibitor
Trade Zofran (2)
serotonin 5-HT3 receptor antagonists
antiemetics
Trade Compazine (2)
conventional antipsychotics
antiemetics
Trade Atarax-Vistaril (2)
antihistamine with anticholinergic
Trade Antivert (2)
antihistamine with antiemetic (anti-nausea)
Trade Reglan
antiemetic
Trade Metamucil (2)
bulk forming agents
laxatives
Trade Dulcolax
laxatives
Trade Colace (3)
laxatives
stimulant laxatives
stool softeners
Trade Lomotil
antidiarrheals
anticholinergics
Trade Imodium
antidiarrheals
Trade Cephulac
laxatives
osmotic
Trade Carafate
gi protectants