G.I. Module 5 Flashcards
Drug class: Action: Neutralize & Decrease Acidity
Antacids
Drug class: Indication: Heartburn and Acid Ingestion Sour Stomach GERD Peptic Ulcer Disease Zollinger Ellison Syndrome Hyperphosphatemia Calcium / Magnesium Deficiency
Antacids
Increased Magnesium can lead to, is contraindicated with (2)
Diarrhea toxicity, Dehydration - dont use in Renal Failure, alcoholics
Increased Aluminum can lead to, used in
Constipation, Dehydration - used for Renal Failure
Increased Calcium can lead to (3)
Bloating, Dehydration, Systemic Alkalosis
Increased Sodium Bicarbonate can lead to (2)
Systemic Alkalosis, Rebound Acidity
What drug class can we use to regulate pH activity
Antacid, preferably 3-4
Frequency of Antacids (3)
12 hours after meals and at the hour of sleep
Has 3 hour duration
Not to exceed 2 week time period
When we have acutely ill patients we must maintain a pH of
7
When using antacids, stool may be _____ in color
chalky
When using enteric meds after antacids what is one thing we must expect
Drug may be broken down sooner than its supposed to because of pH change
Antihistamines block which beta receptor site
H1 beta receptor site
Drug class: Action: Block H2 receptor site on parietal cells decreasing the volume and pH of gastric acid
Antisecretory
Antisecretory meds generally have a
longer duration
Drug class: Indication: Hypersecretory states PUD GERD Zollinger Ellison Decrease amount of HCL being produced
Antisecretory
Frequency of Antisecretory (2)
Short term (4-8 weeks) Prophylactic use (Hour of sleep 10pm)
Side effects of Anti Secretory
Dizziness Headache Disorientation Hallucination Depression Cardiac arrhythmia Decreased bonemarrow MALE BREASTS (Gynecomastia)
Gynecomastia is
Male breasts
What should we monitor for people taking Anti secretory (3)
EKG
Apical pulse
RBC, WBC, Thrombos, CBC
What are some contraindications of Anti secretory meds (3)
Children under 16
Lactating women
Chronic Liver/Kidney disease
Anti secretory meds can alter the results of (2)
allergy test
Gastric acid testing
Nursing implications for giving Anti secretory meds (3)
Give with food except for Nizatidine
Bowel Plan
asses for mood changes
Drug class: Action: Forms a complex that adheres to the ulcer crater, protecting it from irritation
Cytoprotective
Avg dose for Cytoprotective
1g 4x a day
Cytoprotective drugs need an ____________ to be absorbed
acidic environment
Cytoprotective drugs are more effective when
stomach is empty
Because Cytoprotective meds can cause constipation patient should be on
Bowel plan
Best time to take cytoprotective meds are
before meals, or at hour of sleep
If patient is taking a cytoprotective med and an antacid, we should instruct them to
Take antacid 1/2 hour before of 1/2 hour after
Drug class: Action: Reduce gastric acid secretion and protect the mucosal surface of the stomach
Prostaglandins
Drug class: Indication: Prevent gastric ulcer resulting from the use of ASA and NSAIDS
Prostaglandins
Side effects of Prostaglandins include
Abdominal pain
diarrhea
Increased uterine contraction and vaginal bleeding
Before we give our patients a prostaglandins we should make sure of
negative pregnancy
Drug class: Action: Suppress gastric acid secretion by blocking the final step in production of HCI. Acts by binding with Potassium, Adenosine triphosphate and hydrogen in the stomach
Proton Pump Inhibitors
Drug class: Indication: PUD GERD Zollinger - Ellison Syndrome Helibacter Pylori
Proton Pump Inhibitors
Proton Pump Inhibitors are mainly used for
hyper acidic conditions
The two anti secretory drugs classes are
H2 blockers and Proton pump inhibitors
It is recommended to take Proton Pump Inhibitors on a
empty stomach or before meals
Side effects of Proton Pump Inhibitors
Gastric Toxicity
Hypersensitivity
In patients with Helicobacter Pylori there Helidac pack consists of (3)
Bismuth
Tetracycline
Metronidazole
Drug class: Action: Breakdown fats, starches, and protein
Digestants
Drug class: Indication: Replacement in pancreatic enzyme deficiency
Digestants
Digestants should be taken …. because…
with meals because it helps break down food that there eating
Side effects of Digestants are (3)
N+V
Diarrhea
Hyperuricemia
Before administering Digestants we should check for
allergy to pork