GI Infections Flashcards

1
Q
Suprantigen in GI tract
Vomiting, watery non-bloody diarrhoea
B haemolytic colonies on blood agar
From poor food handling
Appears in tetrad clusters G stain
A

Staph Aureus

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2
Q

Reheated fried rice

A

Bacillus Cereus

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3
Q

Bacillus Cereus toxins (x2)

A

Heat stabile (emetic) and Heat labile (diarrhoeal)

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4
Q

Treatment Bacillus Cereus?

A

None, self limiting

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5
Q

Treatment S Aureus?

A

None, self limiting

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6
Q

Canned foods, bacteria in honey (infants)

Preformed toxin

A

Clostridium Botulinum

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7
Q

Preformed toxin, block of ACh release

Descending paralysis

A

Clostridium Botulinum

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8
Q

Treatment of Clostridium Botulinum

A

Antitoxin

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9
Q

Reheated meat, superantigen causes systemic toxicity
Vomiting, watery diarrhoea, lasts 24 hours
rapid onset

A

Clostridium Difficile

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10
Q

Aesculin positive with tumbling motility

A

Listeria Monocytogenes

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11
Q

Unpasteurized dairy, ‘cold enhancement’

A

Listeria Monocytogenes

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12
Q

Treatment of Listeria Monocytogenes

A

Ampicillin (+ ceftriaxone, cotrimoxazole)

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13
Q

E. Coli - ETEC

A

Enterotoxigenic E. coli

Traveller’s diarrhoea

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14
Q

E. Coli - EPEC

A
Enteropathogenic E. coli 
Infantile diarhoea (Paeds)
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15
Q

E. Coli - HUS (3 features)

A

Anaemia, thrombocytopaenia, renal failure

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16
Q

E. Coli - EIEC

A

Invasive dystentry

Enteroinvasive E. Coli

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17
Q

E. Coli - EHEC

A

Haemorrhagic (verotoxin)

Enterohemorrhagic E Coli

18
Q

Multiplies in Peyer’s patches

A

Salmonella typhi

19
Q

Rose spots, slow onset fever, bradycardia

CONSTIPATION

A

Salmonella typhi

20
Q

Treatment of E. Coli

A

Self limiting but can treat with Ciprofloxaxin

21
Q

Treatment of Salmonella

A

Ceftrioxone, or ciprofloxacin

22
Q

Poultry, meat, eggs

non-lactose fermenting

A

Salmonella enteritidis

23
Q

Handling reptiles

A

Salmonella

24
Q

Fever, pain, bloody diarrhoea
Very low effective dose
Production of enterotoxin

A

Shigellae

25
Q

Rice water stool

A

Vibrio Cholerae

26
Q

Increased CAMP, efflux of Cl- into lumen

Massive diarrhoea without inflammatory cells

A

Vibrio Cholerae

27
Q

Raw seafood, common in Japan

Diarrhoea x3 days

A

Vibrio Parahaemolyticus

28
Q

Shellfish handler/diver

A

Vibrio Vulnifcus

29
Q

Treatment of Vibrio Parahaemolyticus/Vulnifcus

A

Doxycycline

30
Q

Bloody foul smelling stool
Prodrome - fever, abdo pain
Oxidase +ve
Poutry, meat, unpasteruised milk

A

Campylobacter Jejuni

31
Q

Treatment of Campylobacter Jejuni

A

Erythromycin or ciprofloxacin

32
Q

Mesenteric adenitis with necrotising granulomas
Farm animals
Extra GI symptoms - arthritis, erythema nordosum

A

Yersinia enterocolitica

33
Q

Flask shaped ulcer

A

Entamoeba Histolytica

34
Q

Motile trophozoite/non motile cyst

4 nuclei

A

Entamoeba Histolytica

35
Q

Treatment Entamoeba Histolytica (x2)

A

Metronidazole + Paramomycin

36
Q

Pear shaped trophozoite

A

Giardia lamblia

37
Q

Travelers, hikers, cruise ships, MSM

Malabsorption of protein and fat - foul smelling non-bloody diarrhoea

A

Giardia lamblia

38
Q

String test

2 nuclei

A

Giardia lamblia

39
Q

Treatment of Giardia lamblia

A

Metronidazole

40
Q

Swimming pools, particularly immunocompromised

Oocysts in stool by Kinyoun Acid Fast Stain

A

Cryptosporidium parvum

41
Q

Treatment cryptosporidium parvum

A

Paromomycin

42
Q

dsDNA, ‘wheel like’

Watery diarrhoea

A

Rotavirus