Antimicrobial Agents

Question 1

Antibiotic vs. skin infection (Staph Aureus)

Answer 1

Flucloxacillin

Question 2

Antibiotic vs. CAP (mild)

Answer 2

Amoxicillin (or macrolide if pen allergic)

Question 3

Antibiotic vs. CAP (severe) (x2)

Answer 3

Co-amoxiclav and clarithromycin (macrolide)

Question 4

Antibiotic vs. Atypical CAP (x2)

Answer 4

Doxycycline + Clarithromycin

Question 5

Antibiotic vs. Bacterial Meningitis (meningococcus/streptococcus)

Answer 5

Ceftriaxone

Question 6

Antibiotic vs. HAP (x2)

Answer 6

Ciprofloxin + Vancomycin

Question 7

Antibiotic vs. Pharyngitis (B haemolytic Strep)

Answer 7

Benzypenicillin

Question 8

Antibiotic vs. UTI (community aquired)

Answer 8

Trimethoprim/Nitrofuratoin

Question 9

Antibiotic vs. UTI (hospital aquired) (x2)

Answer 9

Co-amoxiclav or Cephalexin

Question 10

Antibiotic vs. Colitis (C. diff)

Answer 10

Metronidazole

Question 11

Antibiotic vs. neutropenic sepsis (x2)

Answer 11

Tazocin and Gentamycin

Question 12

Antibiotic vs. severe sepsis (x3)

Answer 12

Tazocin/ceftriaxone + metronidazole

Question 13

Class of drug: Ceftrioxone

Answer 13

Cephalosporin (B lactams)

Inhibit cell wall synthesis

Question 14

Class of drug: Meropenem

Answer 14

Carbapenem (B lactams)

Inhibit cell wall synthesis

Question 15

What is co-amoxiclav?

Answer 15

Amoxicillin (B lactam abx) and Clavulanic Acid (a B lactamase inhibitor)

Question 16

What is Tazocin?

Answer 16

Tazobactam (B lactamase inhibitor) and Piperacillin (ureidopenicillin - B lactam abx)

Question 17

Class of drug: Gentamicin

Answer 17

Aminoglycoside

Inhibits protein synthesis

Question 18

Class of drug: Doxycycline

Answer 18

Tetracycline

Inhibits protein synthesis

Question 19

Class of drug: Erythomycin

Answer 19

Macrolide

Inhibits protein synthesis

Question 20

Class of drug: Clarithromycin

Answer 20

Macrolide

Inhibits protein synthesis

Question 21

Class of drug: Linezolid

Answer 21

Oxazolidinone

Inhibits protein synthesis

Question 22

Class of drug: Ciprofloxin

Answer 22

Fluoroquinone

Inhibits DNA synthesis

Question 23

Class of drug: Metronidazole

Answer 23

Nitroimidazole

Inhibits DNA synthesis

Question 24

MOA: Rifampacin

Answer 24

Inhibits RNA synthesis

Question 25

Class of drug: Colistin

Answer 25

Polymyxin | Cell membrane toxin

Question 26

Class of drug: Daptomycin

Answer 26

Cyclic lipopeptide | Cell membrane toxin

Question 27

Class of drug: Sulfamethoxazole

Answer 27

Sulphonamide | Inhibits folate metabolism

Question 28

Class of drug: Trimethoprim

Answer 28

Diaminopyrimidine | Inhibits folate metabolism

Question 29

What is co-trimoxazole?

Answer 29

Trimethoprim and sulfamethoxazole

Question 30

Treatment for MRSA?

Answer 30

Vancomycin

Question 31

Treatment for S. Aureus (eg. cellulitis)?

Answer 31

Flucloxacillin

Question 32

Treatment for psudomonas spp?

Answer 32

Tazocin

Question 33

Treatment for Legionella?

Answer 33

Macrolide + Rifampicin

Question 34

What gram stain do Carbapenems treat? (eg. Meropenem)

Answer 34

G -ve

Question 35

Treatment vs. intracellular chlamydia?

Answer 35

Doxycyline (tetracycline)

Question 36

Treatment for G+ve if pen allergic?

Answer 36

Erythromycin (macrolide)

Question 37

Treatment for Bacterial Conjunctivitis

Answer 37

Chloramphenicol eye drops

Question 38

Treatment vs. anaerobes and protozoa?

Answer 38

Metronidazole (Nitroimidazole)

Question 39

Treatment for mycobacteria (TB)?

Answer 39

Rifampacin

Question 40

Treatment for PCP (pneumocystitis jirovecii)

Answer 40

sulfamethoxazole

Question 41

DNA synthesis inhibitors | 1 good vs anaerobes, 1 bad vs anaerobes

Answer 41

Fluroquinolones (Ciprofloxin) - bad vs. anaerobes | Nitroimidazoles (Metronidazole) - good vs. anaerobes and protozoa

Question 42

B lactam with anti-pseudomonal activity

Answer 42

Piperacillin (part of Tazocin, an extended spectrum penicillin)

Question 43

Broad spec abx, usually given with a B lactamase inhibitor?

Answer 43

Amoxicillin (part of co-amoxiclav with clavulanic acid)