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Laura Path Recall > Antimicrobial Agents > Flashcards

Antimicrobial Agents Flashcards

1
Q

Antibiotic vs. skin infection (Staph Aureus)

A

Flucloxacillin

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2
Q

Antibiotic vs. CAP (mild)

A

Amoxicillin (or macrolide if pen allergic)

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3
Q

Antibiotic vs. CAP (severe) (x2)

A

Co-amoxiclav and clarithromycin (macrolide)

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4
Q

Antibiotic vs. Atypical CAP (x2)

A

Doxycycline + Clarithromycin

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5
Q

Antibiotic vs. Bacterial Meningitis (meningococcus/streptococcus)

A

Ceftriaxone

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6
Q

Antibiotic vs. HAP (x2)

A

Ciprofloxin + Vancomycin

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7
Q

Antibiotic vs. Pharyngitis (B haemolytic Strep)

A

Benzypenicillin

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8
Q

Antibiotic vs. UTI (community aquired)

A

Trimethoprim/Nitrofuratoin

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9
Q

Antibiotic vs. UTI (hospital aquired) (x2)

A

Co-amoxiclav or Cephalexin

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10
Q

Antibiotic vs. Colitis (C. diff)

A

Metronidazole

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11
Q

Antibiotic vs. neutropenic sepsis (x2)

A

Tazocin and Gentamycin

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12
Q

Antibiotic vs. severe sepsis (x3)

A

Tazocin/ceftriaxone + metronidazole

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13
Q

Class of drug: Ceftrioxone

A

Cephalosporin (B lactams)

Inhibit cell wall synthesis

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14
Q

Class of drug: Meropenem

A

Carbapenem (B lactams)

Inhibit cell wall synthesis

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15
Q

What is co-amoxiclav?

A

Amoxicillin (B lactam abx) and Clavulanic Acid (a B lactamase inhibitor)

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16
Q

What is Tazocin?

A

Tazobactam (B lactamase inhibitor) and Piperacillin (ureidopenicillin - B lactam abx)

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17
Q

Class of drug: Gentamicin

A

Aminoglycoside

Inhibits protein synthesis

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18
Q

Class of drug: Doxycycline

A

Tetracycline

Inhibits protein synthesis

19
Q

Class of drug: Erythomycin

A

Macrolide

Inhibits protein synthesis

20
Q

Class of drug: Clarithromycin

A

Macrolide

Inhibits protein synthesis

21
Q

Class of drug: Linezolid

A

Oxazolidinone

Inhibits protein synthesis

22
Q

Class of drug: Ciprofloxin

A

Fluoroquinone

Inhibits DNA synthesis

23
Q

Class of drug: Metronidazole

A

Nitroimidazole

Inhibits DNA synthesis

24
Q

MOA: Rifampacin

A

Inhibits RNA synthesis

25
Q

Class of drug: Colistin

A

Polymyxin

Cell membrane toxin

26
Q

Class of drug: Daptomycin

A

Cyclic lipopeptide

Cell membrane toxin

27
Q

Class of drug: Sulfamethoxazole

A

Sulphonamide

Inhibits folate metabolism

28
Q

Class of drug: Trimethoprim

A

Diaminopyrimidine

Inhibits folate metabolism

29
Q

What is co-trimoxazole?

A

Trimethoprim and sulfamethoxazole

30
Q

Treatment for MRSA?

A

Vancomycin

31
Q

Treatment for S. Aureus (eg. cellulitis)?

A

Flucloxacillin

32
Q

Treatment for psudomonas spp?

A

Tazocin

33
Q

Treatment for Legionella?

A

Macrolide + Rifampicin

34
Q

What gram stain do Carbapenems treat? (eg. Meropenem)

A

G -ve

35
Q

Treatment vs. intracellular chlamydia?

A

Doxycyline (tetracycline)

36
Q

Treatment for G+ve if pen allergic?

A

Erythromycin (macrolide)

37
Q

Treatment for Bacterial Conjunctivitis

A

Chloramphenicol eye drops

38
Q

Treatment vs. anaerobes and protozoa?

A

Metronidazole (Nitroimidazole)

39
Q

Treatment for mycobacteria (TB)?

A

Rifampacin

40
Q

Treatment for PCP (pneumocystitis jirovecii)

A

sulfamethoxazole

41
Q

DNA synthesis inhibitors

1 good vs anaerobes, 1 bad vs anaerobes

A

Fluroquinolones (Ciprofloxin) - bad vs. anaerobes

Nitroimidazoles (Metronidazole) - good vs. anaerobes and protozoa

42
Q

B lactam with anti-pseudomonal activity

A

Piperacillin (part of Tazocin, an extended spectrum penicillin)

43
Q

Broad spec abx, usually given with a B lactamase inhibitor?

A

Amoxicillin (part of co-amoxiclav with clavulanic acid)

Laura Path Recall (5 decks)

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