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Essential Drugs > GI/GU > Flashcards

GI/GU Flashcards

0
Q

Active ingredients in Gaviscon

A

Sodium Alginate
Bicarbonate (sodium or potassium)
Calcium carbonate

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1
Q

Dose of cyclizine

A

PO 25-100mg upto 3/day

IV 25-50mg upto 3/day

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2
Q

Mechanism of action of lactulose

A

Osmotic laxative (disaccharide of fructose and galactose)

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3
Q

Mechanism of action of Metoclopramide

A

Dopamine D2 receptor antagonist (also 5-HT3 receptor antagonist and 5-HT4 receptor agonist )

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4
Q

Dose of Metoclopramide

A

10-15mg upto 4 times/day

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5
Q

What is Movicol?

A

Polyethylene glycol- iso-osmotic laxative. Also electrolytes

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6
Q

Dose of omeprazole

A

20-40mg daily. Upto 80mg in Zollinger-Ellison syndrome

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7
Q

Ondansetron (5HT3 receptor antagonist) uses

A

Prevent nausea and vomiting caused by chemo/radiation therapy and surgery

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8
Q

Use of prochlorperazine (D2 antagonist)

A

Antiemetic (nausea&vertigo), typical antipsychotic, migraines

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9
Q

Uses of ranitidine (H2 antagonist)

A

Peptic ulcer, GERD, hives, prevent aspiration pneumonia in surgery

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10
Q

What is senna?

A

Stimulant laxative

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11
Q

Key drug interactions of PPIs

A

Reduced absorption of antifungals

Increase plasma concentration of cilostazol (used for intermittent claudication)

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12
Q

Dose of ranitidine

A

Ulcer/reflux: 150mg BD or 300mg nocte
NSAID prophylaxis: 300mg BD
IM: 50mg/6-8h
IV: 50mg in 20mL/6-8h

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13
Q

Dose of domperidone

A

10mg up to TDS

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14
Q

Dose of hyoscine

A

Motion sickness: PO 150-300 micrograms/6h, max 900mg

Hypersalivation: 300 micrograms TDS

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15
Q

Plants with atropine

A

Belladonna, Jimson weed, mandrake

16
Q

Uses of atropine

A

Paralyse and dilate a pupil
Resuscitation for bradycardia, max dose 3mg
Inhibition or salivation and sweating
Treatment of organophosphate poisoning

17
Q

Dose of oxybutynin

A

5mg BD up to QDS

18
Q

Dose of tolterodine

A

2mg BD

19
Q

Dose of prochlorpromazine

A

PO: acute 20mg then 10mg after 2 hours. Prevention 5-10mg 2-3/day. Max 30mg/day
Deep IM: 12.5mg

20
Q

Dose of loperamide

A

Acute: 4mg initially with 2mg after each loose stool for up to 5 days
Chronic: 4-8mg/day
Max 16mg/day

21
Q

Dose of finasteride

A

5mg/day

Essential Drugs (9 decks)

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