GI Emergencies Flashcards

1
Q

What is peritonitis?

A

Inflammation of the serosal membrane that lines the abdominal cavity

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2
Q

How does peritonitis occur if the peritoneal cavity is normally a sterile environment?

A

Primary: Spotaneous inflammation

Secondary: Breakdown of peritoneal membranes leading to foreign substances entering the cavity

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3
Q

What is spontaneous bacterial peritonitis? How do you diagnose it

A

Primary peritonitis often seen in patients with end stage liver disease → an infection of ascitic fluid that cannot be attributed to any intra-abdominal ongoing inflammation

Diagnosed by aspirating ascitic fluid, neutrophil count >250 cells/mm3

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4
Q

Explain how end stage liver disease leads to ascites

A

Cirrhotic liver has 2 main effects:

  • Portal hypertension increases hydrostatic pressure in the capillary
  • Decreased albumin production decreases oncotic pressure in the capillary
  • Results in a net movement of fluid into the peritoneal cavity
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5
Q

What symptoms are associated with spontaneous bacterial periotnitis?

A
  • Abdominal pain
  • Fever
  • vomiting
  • Often mild
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6
Q

What are some of the common causes of secondary bacterial perionitis?

A
  • Peptic ulcer disease (perforated)
  • Appendicities (perforated)
  • Diverticulitis (perforated)
  • Post surgical (especially laproscopic)
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7
Q

What are some of the non-bacterial causes of secondary peritonitis?

A
  • Tubal pregnancy (ectopic rupturing into peritoneal cavity → blood is highly irritant)
  • Ovarian cysts
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8
Q

How does peritonitis present clinically?

A
  • Pain most common symptom
    • may be gradual or acute
    • diffuse if perforated into viscera
  • Patients often lie very still wth shallow breathing and flexed knees to avoid making to pain worse
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9
Q

How would you treat peritonitis?

A
  • Control the infectious source → surgery
  • Eliminate bacteria and toxins → antibiotics
  • Maintain organ system function → may admit to ICU
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10
Q

What are some of the common causes of bowel obstrucion in adults vs children?

A

Children:

  • Intussusception
  • Intestinal atresia

Adults:

  • Adhesions
  • Incarcerated hernias
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11
Q

What is intussusception?

A

When one part of the gut tube telescopes into an adjacent section

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12
Q

How would you treat bowel intusssusception?

A
  • Air enema (pump air into recutm)
  • Surgery if enema unsuccessful
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13
Q

In an intussusception, at what point would you get oedema?

A

As soon as the lymphatic and venous drainage is impaired

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14
Q

What are some of the symptoms of intussusception?

A
  • Abdominal pain
  • Vomiting
  • Haemoatochezia
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15
Q

Where does Meckel’s diverticulum most commonly occur?

A

Located in the distal ileum, 2ft away from the ileocaecal valve

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16
Q

What are the common symptoms of small bowel obstruction?

A
  • Nausea and vomiting (most common, present early)
  • Abdominal distension
  • Absolute constipation comes later
17
Q

What are some of the causes of small bowel obstruction?

A
  • Intra-abdominal adhesions
    • arise after >50% of abdominal surgeries
    • Damage to mesothelium
      • capillary bleeding leads to fibrongen exudate
  • Hernias can narrow lumen enough to cause obstruction
  • Inflammatory bowel disease
    • repeated episodes of inflammation/ healin in Crohn’s
18
Q

How would you diagnose small bowel obstruction?

A
  • History of abdominal pain, crampy, in cyclical periods (due to perilstalsis)
  • Physical examination: distended abdomen, increased/absent bowel sounds, +/- hernia
  • Imaging
19
Q

What are some of the common causes of large bowel obstruction?

A
  • Colon cancer (60%)
  • Diverticular disease (20%) repeated inflammation → narrowing
  • Volvulus (5%) of sigmoid or caecum
20
Q

What are some of the symptoms of large bowel obstruction?

A
  • Change in bowel habit (cancer)
  • Abdominal distension
  • Crampy abdominal pain
  • Nausea and vomiting comes later if ileocaecal valve incompetent and allows backflow
  • Typically gradual unless volvulus which is acute onset
21
Q

What is volvulus?

A

Where part of the colon twists on its mesentry, resulting in bowel obstruction, can result in infarct

22
Q

How can a high fibre diet predispose someone to volvulus?

A

High fibre diets cause bulkier stools adding weight into the large intestine which can cause it to twist on its axis

23
Q

How does age change whether the bowel obstruction is more likely to be large or small?

A

Small bowel more commonly obstructed in younger age group

Large bowel more common obstructed in older age group

24
Q

How do you differentiate between the small and large bowel on Xray?

A

Small bowel:

  • smaller distensions
  • central
  • plicae circularis

Large bowel:

  • around the periphery
  • largery distension
  • haustra
25
Q

What is acute mesenteric ischaemia and what are some of the causes?

A

Symptomatic reduction in blood supply to the GI tract

More common Females (75%) and if there is a history of peripheral vascular disease

  • Acute occlusion (70%) - arterial embolism of SMA
  • Non occlusive ischaemia - low cardiac output
  • Mesenteric venous thrombosis
26
Q

Which area is particularly vulnerable to acute mesenteric ischaemia?

A

The splenic flecture as it has the least colateral blood supply (watershed area)

27
Q

What clinical findings would indicate acute mesenteric ischaemia?

A
  • Abdominal pain that is disproportionate to the clinical findings
    • classically comes on 30 mins after eating and lasts 4 hours
  • Nausea and vomiting
  • Pain often left sided as splenic flexure is fragile
28
Q

How would you treat acute mesenteric ischeamia?

A
  • Surgery - resection of ischaemic bowel
  • Thrombolysis/ angioplasty (if caught at early stages)
  • Mortality is high
29
Q

Which artery is vulnerable to erosion by a peptic ulcer in the 1st part of the duodenum?

A

Gastroduodenal artery

30
Q

Where does blood from oesphageal varices drain to?

A

Portal drainage: oesophageal veins drain into the left gastric vein and into the portal vein

Systemic drainage: oesophageal veins drain to azygous system, drains into superior vena cava

31
Q

How would you treat oesophageal varices?

A
  • Band Ligation
  • If not controlled by band ligation insert a TIPS (transjugular inrahepatic portosystemic shunt)
    • expandable metal placed in teh liver to bridge the portal vein and hepatic vein which decompresses portal vein pressure
32
Q

What is an abdominal aortic aneurysm? How does it typically arise?

A

A permanent pathological dilation of the aorta with a diameter >1.5 times the expected AP diameter of that segment

Typically due to the degeneration of the elastin and collagen of the media layer of the arterial wall

33
Q

Give some risk factors for developing an AAA

A
  • Male
  • Inherited risk
  • Increasing age
  • Smoking
34
Q

In which location do most AAAs occur?

A

Infrarenal (90%)

35
Q

What are the symtpoms of AAA?

A

Usually asymptomatic until acute expansion or rupture

Can cause symptoms by compressing nearby structures:

  • nausea, urinary frequency and backpain

Usual presentation when ruptured:

  • abdominal pain +/- flank/ groin pain
  • back pain
  • pulsatile abdominal mass
  • transient hypotension → syncope
  • sudden cardiovascular collapse
36
Q

How can you diagnose AAA?

A
  • Physical examination
  • Ultrasonography (pouch of morrison good place)
  • CT
  • Plain x-ray (if aneurysm is calcified)
37
Q

How would you treat AAA?

A
  • Non surgical: smoking cessation, hypertension control
  • Surveillance monitor for size
  • Surgery
  • Endovascualr repair - reline the aorta using an endograft → inserted through the femoral artery
  • Open surgical repair - add synthetic graft