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Pharmacology > GI Drugs > Flashcards

GI Drugs Flashcards

1
Q

Aluminium and magnesium hydroxide class

A

Antacid

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2
Q

Antacid mechanism of action

A

Gastric acid neutralisation

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3
Q

Antacid indication(s)

A

Dyspepsia, heartburn

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4
Q

Antacid adverse effect(s)

A

Nausea

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5
Q

Calcium carbonate class

A

Antacid

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6
Q

Sodium alginate with sodium bicarbonate class

A

Antacid + alginate

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7
Q

Antacid + alginate mechanism of action

A

Gastric acid neutralisation

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8
Q

Antacid + alginate indication(s)

A

Gastric reflux

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9
Q

Antacid + alginate adverse effect(s)

A

Abdominal distension

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10
Q

Ranitidine class

A

H2 receptor antagonist

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11
Q

H2 receptor agonist mechanism of action

A

Blockade of gastric H2 histamine receptors

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12
Q

H2 receptor agonist indication(s)

A

Stomach ulcers

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13
Q

H2 receptor agonist adverse effect(s)

A

Dizziness

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14
Q

Cimetidine class

A

H2 receptor antagonist

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15
Q

Omeprazole class

A

Proton pump inhibitor (PPI)

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16
Q

PPI mechanism of action

A

Blockade of stomach acid transporters

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17
Q

PPI indication(s)

A

Stomach and duodenal ulcers, gastric reflux

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18
Q

PPI adverse effect(s)

A

Headache, diarrhoea

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19
Q

PPI interaction(s)

A

Warfarin

20
Q

Lansoprazole class

A

Proton pump inhibitor

21
Q

Pancreatin class

A

Pancreatic enzymes

22
Q

Pancreatin mechanism of action

A

Restoration of pancreatic enzymes

23
Q

Pancreatin indication(s)

A

Pancreatic insufficiency - cystic fibrosis, pancreatitis

24
Q

Methylcellulose class

A

Bulk laxative

25
Q

Bulk laxative mechanism of action

A

Water absorption in intestinal lumen to bulk stools

26
Q

Bulk laxative indication(s)

A

Constipation

27
Q

Isphagula husk class

A

Bulk laxative

28
Q

Docusate class

A

Faecal softener

29
Q

Faecal softener mechanism of action

A

Stimulates water and electrolyte secretion into intestinal lumen

30
Q

Faecal softener indication(s)

A

Constipation

31
Q

Arachis oil class

A

Faecal softener

32
Q

Macrogol (PEG) class

A

Osmotic laxative

33
Q

Osmotic laxative mechanism of action

A

Water retention in intestinal lumen

34
Q

Osmotic laxative indication(s)

A

Constipation

35
Q

Osmotic laxative adverse effect(s)

A

Stomach cramps

36
Q

Osmotic laxative interaction(s)

A

Antiepileptics

37
Q

Lactulose class

A

osmotic laxative

38
Q

Magnesium sulphate, magnesium hydroxide class

A

osmotic laxative

39
Q

Bisacodyl class

A

stimulant laxative

40
Q

Stimulant laxative mechanism of action

A

increase intestinal motility

41
Q

Stimulant laxative indication(s)

A

constipation

42
Q

Stimulant laxative adverse effect(s)

A

nausea

43
Q

Senna class

A

stimulant laxative

44
Q

Loperamide class

A

opioid anti-motility agent

45
Q

Opioid anti-motility agent mechanism of action

A

agonist for u-opioid receptors in myenteric plexus. Blocks intestinal muscarinic receptors

46
Q

Loperamide indication(s)

A

diarrhoea

47
Q

Codeine (GI) class

A

opioid anti-motility agent

Pharmacology (5 decks)

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