GI Drugs

Question 1

TERM a drug that inhibits GI absorption of drugs, toxins or chemicals by attracting and holding them to its surface

Answer 1

adsorbent

Question 2

TERM an area of the brain that activates the vomiting center when stimulated by toxic substances in the blood

Answer 2

CRTZ- chemoreceptor trigger zone

Question 3

TERM the act of vomiting

Answer 3

emesis

Question 4

TERM wave of contractions that propels content along the digestive tract

Answer 4

peristalsis

Question 5

TERM periodic, repeating pattern of intestinal constrictions that serves to mix and churn the contents

Answer 5

segmentation

Question 6

TERM a drug that induce vomiting

Answer 6

emetic

Question 7

TERM a drug that stop vomiting / diarrhea

Answer 7

antiemetic

Question 8

TERM bacteria that is healthy for the immune system

Answer 8

probiotics

Question 9

activates the vomiting center, administered in the conjunctival sac, orally, or IV. Induction of vomiting, what category?

Answer 9

apomorphine 
central acting (CRTZ)

Question 10

induces vomiting within 3-5 min mainly with cats, off label

Answer 10

xylazine

central acting

Question 11

prevents motion sickness in dogs, also used as a tranquilizer and antiemetic

Answer 11

phenothiazine derivative

chlorpromazine

Question 12

antiemetic for parvo, uremic vomiting, tx gatric motility disorder, central: block CRTZ, strengthen cardiac sphincter in stomach. should not be used if obstruction is suspected

Answer 12

procainamide derivative

metoclopramide (reglan)

Question 13

found on the vagal nerve terminal and in the CRTZ mainly used as an entiemetic when animals are on chemotherapy

Answer 13

serotonin receptor antagonist

ondansetron (zofran)

Question 14

blocks binding of substance P to NK-1 receptors in the CRTZ - tx in vomiting dogs from motion sickness

Answer 14

maropitent citrate (cerenia)

Question 15

histamine activate H2 receptors to stimulate gastric parietal cells to secrete hydrochloric acid decreasing irritation of the stomach mucosa

Answer 15

famotidine (pepcid)

Question 16

a disaccharide that forms a paste that bind to the surface of gastric ulcers bind better in an acidic event

Answer 16

gastromucosal protectants

sucralfate (carafate)

Question 17

appetite stimulant primarily in cats

Answer 17

cyproheptadine

Question 18

synthetic antibacterial and antiprotozoal agent . Tx of giardiasis, thrichomoniasis (do not give a pregnant animal)

Answer 18

metronidazole (flagyl)

Question 19

inhibits histamine at H2 receptors of gastric parietal cells (least potent) used for tx or prevention of gastric, abomasal or duodenal ulcers

Answer 19

H2 receptor antagonist

cimetidine