GI disorders Flashcards
hiatal hernia
> stomach pushes up through esophageal hiatus and goes into thoracic cavity
- difficulty swallowing/reflux disease
- 2 kinds: sliding and paraoesophageal
hiatal hernia presents
- asymptomatic
- dysphagia
- GERD like
hiatal hernia diagnosis
- endoscopy
- barium swallowing (lights up on xray)
hiatal hernia treatment
- reduce acid in stomach (proton pump/histamine blockers)
- surgery
- lifestyle change > small meals
- surgery: fundoplication
GERD
> stomach contents move backward into esophagus
- sphincter opens from relaxing
GERD manifestations
- dysphagia: hard to swallow
- heartburn/epigastric pain (pyrosis)
- indigestion after meals
- laryngitis
- aspiration pneumonia
GERD diagnosis
- history
- acid suppression trial
GERD treatment
lifestyle changes (no coffee, alc, smoking) - raise HOB, eat early before laying down, small meals
- PPI and H2 blockers
- surgery (fundoplication)
GERD complications
Barrett’s esophagus: metaplastic change (squamous to columnar) and can lead to cancer
esophageal cancer
- rare
- 2 types: top of esophagus (smoking, alc use) and adenocarcinoma in lower esophagus (barrett’s)
- higher chance with age
- men is more common > GERD, smoking, drinking
esophageal cancer manifestations
- difficulty swallowing
- weight loss
- change in eating patterns
esophageal cancer diagnosis
- endoscopy
- biopsy
esophageal cancer treatment
- surgical reception of esophagus
- chemo/radiation
gastritis
- acute: short term, likely to resolve
- chronic: lasts a long time
acute erosive gastritis
- cause inflammation of stomach lining
- from: medications (NSAIDS), bacterial infection, steroids, alc, chemo, radiation, stress
acute erosive gastritis manifestations
- epigenetic pain
- nausea and vomiting
acute erosive gastritis diagnosis/treatment
- history
- endoscopy
Tx: remove cause
chronic gastritis
- inflammation to stomach lining
> helicobacter pylori infection (gram neg bacteria with flagellations) - erode mucosa > lead to erosions
- hispanic, african american, aging people
flagellations
allow bacteria to burrow into mucosal lining then secretes ammonia (urease) to protect self from acid
chronic gastritis diagnosis
- endoscopy
- breath test
- biopsy
- test stool antibodies
chronic gastritis treatment
- antibiotics (long term)
chronic gastritis over time
- atrophy of glands in stomach that secrete mucus (protection)
chronic gastritis over time cause
- autoimmune response (attack parietal)
- intrinsic factor decreased (good for absorption)
- anemic (cant absorb B12)
chronic gastritis over time symptoms
- no unique symptoms
- heartburn/epigastric pain
- peptic ulcers
chronic gastritis over time diagnosis
- endoscopy
- check B12 levels in blood test
chronic gastritis over time treatment
- acid reducers
- B12 and iron supplement
- PPI and H2 blockers
peptic ulcer disease
> if gastritis isnt treated
- ulcers can be in stomach and small intestine (duodenum)
- common with h. pylori and NSAIDS
- from stress, alc, smoking, caffeine