GI Disorders Flashcards
What are some skin related changes that could indicate a GI disorder?
- discolorations
- rashes
- jaundice
- increased bruising
- increased tendency to bleed
What are important lab tests to diagnose for GI disorders?
- CBC
- clotting factors (PT)
- electrolytes (Na+, K+)
- liver enzyme assay – will be elevated with liver disease
- aspartate (AST)
- alanine aminotransferase (ALT)
- serum amylase – elevated with pancreatic disorders
- serum lipase – elevated with pancreatic disorders
- bilirubin – elevated with impaired liver secretions
- produced during RBC breakdown
- ammonia – elevated can cause brain problems
- hepatic encephalopathy
- altered LOC
- oncofetal antigens – cancer markers
- urine tests
- amylase
- urine urobilinogen – only present in urine if there is a hepatic or biliary obstruction
- stool tests
- fecal occult blood test
- ova parasites
- C. diff infection
What 3 values are evaluated in a bilirubin panel?
- total bilirubin
- indicates
- hemolysis
- biliary obstruction
- liver damage
- indicates
- conjugated bilirubin
- indicates
- biliary obstruction
- indicates
- unconjugated bilirubin
- indicates
- hepatic damage
- hemolysis
- indicates
What is GERD? What population does GERD mostly affect?
– GERD: backward flow of gastrointesetinal contents into the esophagus
- often caused by
- relaxed lower esophageal spincter tone
- elevated gastric volume
- elevated intra-abdominal pressure
– mostly affects middle-aged to older adults
What are the major symptoms of GERD?
- heartburn
- dyspepsia
- regurgitation
- hypersalivation
- dysphagia (chronic GERD)
What are some interventions for GERD?
- diet changes
- limit consuming large meals
- eat meals slowly
- don’t eat 3H before bed
- lifestyle changes
- elevate HOB for sleep
- sleep in left lateral decubitus position
- reduce weight
- wear nonbinding clothing
- stop smoking and drinking alcohol
- drugs
- antacids – neutralize gastric acid
- H2 antagonists – decrease gastric acid secretion
- PPIs – long-acting inhbition of gastric acid secretion
- prokinetic GI stimulants – increase gastric emptying and improve peristalsis
What is a hiatal hernia? What is the difference between a sliding hiatal hernia and a rolling hiatal hernia?
– hiatal hernia: protrusion of the stomach through the esophageal hiatus of the diaphragm into the thorax
– sliding hiatal hernia: esophagogastric junction and a portion of the fundus of the stomach slide upward through the esophageal hiatus into the thorax
- most common type of hiatal hernia
– rolling hiatal hernia: fundus rolls into the thorax beside the esophagus
- decreases lung capacity
- increases risk of volvulus
What are the signs and symptoms of hiatal hernias?
– sliding hiatal:
- heartburn
- regurgitation
- dysphagia
- belching
– rolling hiatal:
- fullness/breathlessness after eating
- chest pain
- worsening symptoms in recumbent position
How are hiatal hernia diagnosed?
- barium swallow/esophagogram with contrast
- endoscopy
- shows protrusion of stomach through diaphragm
What are some interventions for hiatal hernias?
- usually resolved surgically
- laprascopic fundoplication
- drugs
- antacids
- H2 antagonists
- diet therapy
- avoid eating late at night
- avoid foods that cause reflux
- weight management
- elevate HOB for sleep
- remain upright for several hours after eating
- avoid straining and vigorous exercise
- avoid nonbinding clothing
What is the main priority with fundoplication surgery?
prevention of respiratory complications
What is gastritis? Differentiate between acute and chronic.
– gastritis: inflammation of the gastric mucosa
- acute: caused by bacterial infection, onset of H. pylori, or long-term use of NSAIDs (inhibit prostaglandin production)
-
chronic: antibodies cause an autoimmune response
- type A gastritis
How is gastritis diagnosed?
endoscope with biopsy to detect H. pylori = gold standard
What are the main signs and symptoms of gastritis?
- epigastric pain
- acute – rapid onset
- chronic – relieved with food
- anorexia
- N/V
– acute:
- hematemesis
- dyspepsia
- gastric hemorrhage
– chronic:
- intolerance to fatty/spicy foods
- pernicious anemia (B12 anemia)
- neuro issues – caused by lack of B12
What are some interventions for gastritis?
- treat etiology
- main tx
- drugs
- H2 antagonists
- antacids
- mucosal barrier fortifiers
- PPIs
- PPI triple – treats H. pylori infection
- 2 types of antibiotics
- 1 type of PPI
- diet changes
- limit foods that cause distress
- limit smoking and alcohol
- reduce stress
What is peptic ulcer disease (PUD)?
mucosal lesion of the stomach or duodenum – gastric mucus is no longer able to protect epithelium from HCl, pepsin, and H. pylori
What is the most common cause of gastric ulcers? What causes stress ulcers?
– cause = delayed gastric emptying
– stress ulcers caused by:
- acute medical crisis
- trauma
- head injury
- sepsis
- NPO
What are the signs and symptoms of PUD?
- epigastric tenderness midline b/w umbilicus and xiphoid process
- dyspepsia
- sharp, burning, gnawing pain