GI Bleeding Flashcards

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1
Q

What is the defining boundary of upper or lower GI bleeding?

A

Ligament of Trietz

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2
Q

What is the most common cause of upper GI bleed? And what two things cause it?

A

Peptic ulcer disease

Most common causes: H. pylori and NSAIDS

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3
Q

What are other causes of upper GI bleeding?

A
Esophageal varices
Mallory-Weiss tears (nontransmural)
Esophageal rupture
Boerhaave's syndrome (transmural perforation)
Gastric varices
Angiodysplasia
Cancer
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4
Q

What is angiodysplasia?

A

An artery and vein come together without the architecture of a capillary to buffer the pressure differences.

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5
Q

What is the first priority in dealing with esophageal varices?

A

Stopping blood loss and restoring volume

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6
Q

What is the mainstay of urgent treatment of esophageal varices rupture?

A

Therapeutic endoscopy

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7
Q

What is the difference between mallory-weiss and boerhaave’s?

A

Boerhaave’s is full thickness rupture and is much more serious.

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8
Q

What should you suspect in a pt presenting with hematemesis, coffee ground vomiting, melena, or hematochezia? Maybe anemia, fatigue, chest pain, syncope, SOB?

A

Upper GI bleed due to peptic ulcer disease

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9
Q

What medications increase the risk of peptic ulcers?

A

ASA and NSAIDS (x4)

SSRIs, corticosteroids, and anticoagulants

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10
Q

What is the the diagnostic and treatment option of first choice in the emergency evaluation of upper GI bleed?

A

Upper endoscopy

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11
Q

What criteria does the Glasgow-Blatchford score use?

A
Hemoglobin
Systolic BP
Pulse
Serum BUN
Melana or syncope
Past or present liver disease or CHF
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12
Q

What does melenic stool most likely indicate?

A

4x more likely to come from an upper GI bleed. Black tarry stool that has been in the GI tract for at least 8 hours.

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13
Q

What does hematochezia indicate and how is it different from melena?

A

Bright red or maroon colored stool is a sign of active GI bleed. 6x more likely to come from a lower GI bleed.

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14
Q

Where do most lower GI bleeds originate?

A

Colon - 85%
Upper GI - 10%
SI - 3-5%

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15
Q

Where do diverticula most commonly occur and where are they most problematic?

A

75% occur on the left side of the colon, but 50-90% of lower GI bleeding from diverticulosis comes from the right side of the colon.

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16
Q

What kind of cancer should be suspected with lower GI bleeding?

A

Colorectal adenocarcinoma (3rd MC cancer in US)

17
Q

Which form of inflammatory bowel disease more commonly has lower GI bleeding?

A

Ulcerative colitis

18
Q

Who is most at risk for ischemic colitis?

A

> 60 y/o

19
Q

What factors increase risk of morbidity and mortality with a lower GI bleed?

A

Poor renal function
>60 y/o
Abn, low BP, and persistent bleeding within first 24 hours of presentation

20
Q

What is the diagnostic method of choice for lower GI bleed?
For hemodynamically unstable pts?
If colonoscopy fails to identify a bleeding site?

A

Colonoscopy
Angiography (w/ or w/o radionuclide scan)
Angiography