GI Bacteria Flashcards
Streptococcus Viridans group
- Gram+, cocci,
- catalase neg,
- alpha hemolytic, no lancefield grou,
- optochin resistant, bile insoluble, non capsulated (quelling neg)
spp: mitis, mutans, salivarius, sanguis, anginosus
Dental plaque. Endogenous mouth, upper resp and intestinal. Oral surgery.
- low virulence, no toxins
- formation of biofilm
- attachment. produce dextrans and levans
- produce acid from sugar demineralize enamel
- subacute endocarditis
Mumps
Paramyxoviridae –ssRNA, enveloped, Helical. polymophic
nonsegmented, Fusion peplomer, Hemagglutinin attachment, Neuraminidase release, fragile and distorted in images.
one antigenic type: life long immunity
Respiratory human spread contagious -7days.
local replications and viremia systemic involvement
- Panrease -diabetes?
- Parotid - multiply in ductal epithelial clells wsweeling and pain
- testes/ovaries
- peripheral nerve, CNS
- eye, inner ear,
Vaccine MMR/MMRV (two doses)
Helicobacter Pylori
gram neg, rod, motile polar flagella, **urease pos, ** catalase, oxidase pos.
Human, oral fecal lifelong infection.
- mucinase: hydrolyzes mucopolysaccharide substances
- phospholipase: hydrolyses phophslips
- urease, breaks urea to Co2 and NH3. ammonia neutralizing gastric acid and damages epitheliaum.
- Cytotoxin associated gene (CagA) destro epethilial cell sytoskeleton
- Type IV secretion system assists in injecting CagA to epithelial cells
- LPS. inflammatory response infiltration with PMN and mononuclear cells
- exopsed epithelial further destroyed by gastric digestive enzymes and acid.
- chrinic superficia gastritis
- peptic ulcer
- lymphoproliferative MALT
- chrnic atrophic gastritis -> gastric adenoma (CagA strains)
not found in stool - stain biopsy. Ag monoclonal Ab not specific. 90% sero positive. Urease breath test radioactive urea expire Co2.
Staphylococcus Aures Toxin
Grm ++, cocci, cluster of grapes, catalase +, growth at 7.5%.
Coagulase +, beta hemolytic, manitol fermentor, golden yellow/white.
Bacillus Cereus
Clostridium Perfringens
Clostridium Botulinum
