GI and Nutrition Flashcards
What is the difference btwn a probiotic and prebiotic? Give an example of a probiotic.
Probiotic = live micro-organism which can survive in digestive tract and confer health effect when consumed in adequate amounts (e.g. lactobacilli, bifidobacteria)
Prebiotic = nonviable food component that can confer a health benefit
What factors affect the development/composition of gut microflora? (5)
type of delivery infant diet (breastfed vs formula) environment gestational age antibiotics
How do probiotics work?
modify gut microflora by lowering colonic pH through production of short-chain fatty acids
What is the role of the gut microflora?
- contributes to gut’s barrier function (decreases gut permeability)
- modulates guts immune function
For what conditions is there definite evidence for benefit to using probiotics? What conditions might have evidence? No conclusive evidence?
Have evidence for probiotic use in:
- antibiotic-associated diarrhea
- acute infectious viral diarrhea
- preventing NEC
May be evidence for:
- colic
- IBS
- preventing relapse in pts with recurrent C diff infections
No conclusive evidence:
- atopic disease
- travellers diarrhea
- preventing food allergies
- treating allergic colitis
Define antibiotic-associated diarrhea.
> 3 loose stools/day for at least 2 days occurring up to 2 weeks after initiation of antibiotics
What effect do probiotics have in acute viral diarrhea?
-decreased duration of diarrhea (btw 17-30 hrs less) and there is greater benefit if initiated early (
In which premature babies could you consider probiotics?
-preterm babies>1kg at risk for NEC
True or false: Lower counts of lactobacilli and bifidobacteria are found in children with atopic dermatitis compared with healthy controls.
True
True or false; We should recommend adding probiotics to infant feeds to prevent allergic disease or food hypersensitivity.
False. There is insufficient evidence to make this recommendation.
What are side effects of probiotics?
-can cause systemic or local infections in critically ill or immunocompromised patients
True or false: Effect of probiotics is strain and disease specific.
True
What are the benefits of breastfeeding for baby? (7)
Decreased incidence of:
- bacterial meningitis
- bacteremia
- AOM
- UTI
- resp infections
- decrease in SIDS
- enhanced performance on neurocognitive testing
For each month of exclusive breastfeeding this may reduce hospital admissions secondary to infection by 30%.
What are benefits of breastfeeding for mums? (4)
- decreased incidence of breast and ovarian cancer
- delay in return of ovulation
- greater postpartum weight loss
- economical
What does CPS recommend for breastfeeding?
Exclusive breastfeeding for the first 6 months of life and continued breastfeeding with appropriate complementary foods for up to 2 yrs and beyond
What are the 10 steps to successful breastfeeding? (as per WHO and UNICEF)
- Have written BF policy routinely communicated to all staff.
- Train all staff in skills necessary to implement BF policy
- Inform all pregnant women about the benefits and management of breastfeeding
- Help mothers initiate BF within half an hour of birth
- Show mums how to BF and maintain lactation even when separated from their infants
- Give newborns no food or drink other than breastmilk, unless medically indicated
- Practice rooming-in, allow mums and babes to stay together 24 h a day
- Encourage BF on demand
- Give no artificial soothers to BF infants
- Foster the establishment of BF support groups and refer mothers to them at d/c from hospital or clinic
What does it take to be considered a Baby-Friendly institution?
follow each of the 10 steps of successful BF for at least 80% of all women and babies
Discuss some of the features of the international code of marketing breast-milk substitutes.
- no free samples/gifts to mums or HC workers
- no promotion of products in HC facilities
- no words or pictures idealizing artificial feeding
- all info on artificial feeding should be factual and explain the benefits of BF
- complementary foods are not to be marketed in ways that undermine exclusive and sustained BF
- financial assistance from the infant feeding industry may interfere with professionals’ unequivocal support for BF
How should we approach breastfeeding in NICU babies?
If not medically feasible to do rooming-in and BF then if not enough of mum’s own milk then use PHDM.
Discuss the timing of pacifier introduction in breastfed babies.
Prudent to delay intro of pacifiers until after BF is established.
What is kangaroo care and when should it be done?
skin-to-skin contact
within 30 mins of birth
What are the contraindications to breastfeeding? (4)
HIV-positive
cytotoxic chemo
radioactive isotopes/radiation therapy
classic galactosemia
Can you breastfeed if mum smokes, drinks or baby has PKU?
Smoking – BF may mitigate some of the negative effects of smoking on the health of baby so keep BF
Alcohol - limit this as freely passes into breastmilk
PKU – continue breastfeeding to supplement a low-phenylalanine formula along with strict monitoring of phenylalanine levels
What are phytoestrogens?
Plant-derived substances found in soy that have estrogenic activity. Are isoflavone class and are weak estrogens.
Present in large amounts in soy-formula. 94% in soy formula are biologically inactive. Are activated once ingested but only 3% in the plasma are biologically active.
Infants do not accumulate phytoestrogens in the plasma.