Community Paediatrics Flashcards
What is primary nocturnal enuresis? secondary?
- involuntary discharge of urine at night by children old enough to be expected to have bladder control
- primary = bladder control has never been attained
- secondary = incontinence recurs after at least 6 months of continence
When can you start saying a child has enuresis?
-regular bed wetting (more than 2x/wk) beyond age of 5 yrs
How common is bedwetting?
- 10-15% of 5 yr olds
- 6-8% of 8 year olds
- 1-2% of 15 year old
When should you treat enuresis with pharmacotherapy and/or alarms?
-only if it poses a significant problem of the child
What routine tests should be ordered in a child with primary nocturnal enuresis?
-none if the hx and px are completely reassuring
What are RF for primary nocturnal enuresis?
positive family hx of the same
How does an alarm for nocturnal enuresis work?
-alarm goes off when the child starts to void and it will teach the child to wake up to the alarm and then by approximation to wake up to the sensation of a full bladder
How much do bed-wetting alarms cost?
$80
In which age group are bed-wetting alarms most effective?
kids >7-8 yrs
How would you tell a family to use a bed-wetting alarm?
- continued use for 3-4 months
- warn is often an initial improvement of decrease in urine output as opposed to being totally dry
- continue until there have been 14 consecutive dry nights
What is the cure rate when using a bed-wetting alarm for primary nocturnal enuresis? What is the cure rate if pt relapses?
cure rate is 50%, rate is the same for relapses
What are down sides of the bed wetting alarm for primary nocturnal enuresis?
- 50% cure rate
- needs a commitment from the entire family b/c can wake everybody up
In which pts should the bed wetting alarm for primary nocturnal enuresis be recommended?
-older, motivated children from motivated families for whom more simple measures are not successful
What is desmopressin?
-synthetic analogue of antidiuretic hormone
What are side effects of desmopressin?
- headache
- abdo pain
- stuffiness
- epistaxis
What is the dose of desmopressin for nocturnal enuresis?
-desmopressin acetate 200-600 microgram
For which populations do you need to use desmopressin with extreme caution?
- kids with osmoregulation or fluid balance problems
- kids with CF
What instructions should you give to parents about desmopressin for their kids?
-avoid consuming fluids for one hour before and 8 hrs after taking desmopressin
When should desmopressin b prescribed for kids with primary nocturnal enuresis?
- short-term only
- camps
- sleepovers
What are treatment options for patients with primary nocturnal enuresis?
- alarm systems
- desmopressin acetate
- imipramine hydrochloride
For which patients with nocturnal enuresis could imipramine be prescribed to and at what dose? How long should they trial it before adjusting the dose?
Give to older, distressed kids if other treatments unsuccessful or contraindicated
- kids 6-12 yrs = 25 mg (max 50 mg)
- kids >12 yrs = 50 mg (max 75 mg)
- give dose 1-2 hrs before bedtime
- 2 week trial (maximal effect is noted within 1 wk)
What are side effects of imipramine?
- personality changes
- emotional lability
- irritability
- anxiety
- disturbed sleep patterns
- h/a
- changes in appetite
- RARE: sz, coma, cardiac arrhythmia from OD
Should you use sticker charts for rewarding dry nights in kids with nocturnal enuresis or ‘lifting’ (waking kid to void in the toilet)?
- they may contribute to poor self esteem
- discuss with parents about potential adverse effects before instituting this
What are some behavioural modifications that can be recommended for primary nocturnal enuresis?
- clarify the goal of getting up at night and using the toilet
- assure the child’s access to the toilet
- avoid caffeine-containing foods and excessive fluids before bedtime
- take the child out of diapers (training pants are ok)
- incude the child in the morning cleanup in a non punitive manner
- preserve their self-esteem
- if the pt is not distressed then they do not need treatment
What is preferred to transport a threatened preterm labour in utero or after baby is born?
in utero
Why is there a need for a specialized neonatal transport team?
- enhanced survival of neonate
- fewer adverse events
What is the typical make up of a neonatal transport team?
RT and RN
(better with an RN led team than a physician led team)
RTs more successful at incubations than residents
What equipment needs to be included for a neonatal transport?
-portable isolette
-ventilator
-medical air
-oxygen
iNO
-suction
-monitors for vital signs
-pulse oximetry
-capnography
-defibrillator
-point of care testing
-satellite or cell phone
What are physiological side effects of transport for the baby and how can these be prevented or minimized?
- hypothermia - use a warming mattress
- ambient noise - ear muffs
- vibrations - air foam mattress and gel pillow
Who is legally responsible for the baby being transported from the community to a territory care setting?
- tertiary institutions share the medicolegal responsibility as soon as they are aware of them
- referral and transport team shares legal responsibility during stabilization
What is used for quality assurance of neonatal transport teams?
- central access point
- database that captures severity of illness, transport times etc
What is tongue-tie?
ankyloglossia = abnormally short lingual frenulum which can cause decreased tongue mobility
What are the criteria to diagnose ankyloglossia?
-no universally accepted definition or criteria
How common is ankyloglossia?
4.2-10.7% of newborns
What are the concerns about ankyloglossia?
- anecdotal reports linking it to poor latch, maternal nipple pain and trauma, suboptimal infant weight gain, infant breast refusal, low maternal milk supply due to poor milk removal
- no absolute relationship btwn ankyloglossia and breastfeeding difficulties
- remember to rule out other oral anomalies
What is the management of ankyloglossia?
- usually conservative with some lactation support
- if there are signifiant breastfeeding difficulties then there is some evidence for frenotomy
What is a frenotomy and who should do it?
- simple incision or snipping of tongue tie is most common
- should be done by ENT or trained physician
- give analgesia during procedure
- some more complicated procedures exist
What are the complications of frenotomy for tongue-tie?
- bleeding
- infection
- injury to Wharton’s duct
- post operative scarring (which can limit tongue movement further)
What % of boys and what % of girls will have had a UTI by age 7 years?
- 8% of girls
- 2% of boys
Which children should get antibiotic prophylaxis after a UTI?
- not routinely recommended
- consider it for kids with grade IV or V VUR or significant urological abnormality
If you are going to use antibiotics for prophylaxis after UTI which one should you use and for how long?
-use for 3-6 months and reassess if the abnormality still exists
-TMP-SMX or nitrofurantoin
(nitrofurantoin needs to compounded into suspension in a special pharmacy)
What is the dose of prophylactic antibiotics for UTI?
- septra or nitrofurantoin
- no specific guidelines
- traditionally used 1/4 to 1/3 of the daily total treatment dose but given once a day
What do you do with antibiotic prophylaxis in a child who grew a bug resistant to the prophylaxis?
-stop or change the prophylaxis even if you think the bug is a contaminant
What criteria should you use to do a UA and UCx in kids
-fever >39 without a source
What criteria should you use to do a UA and UCx in kids > 3 yrs?
- dysuria
- frequency
- hematuria
- abdo pain
- back pain
- new daytime incontinence
What is the contamination rate of bag samples for urine? What is the utility of a bag sample?
63%
-a negative bag culture rules out a UTI but a positive result is not useful
What do you look for on a dipstick (macroscopic urinalysis) that is suggestive of a UTI?
- positive nitrites test makes UTI very likely
- positive leukocyte esterase (as a indirect measure of pyuria)
What are nitrites and what causes false negative nitrites on a dipstick?
- nitrites are a breakdown product of nitrates that are broken down by gram-negative bacteria
- are very specific for UTI (98%)
- False negatives: if bladder emptied frequently, if is gram-positive organism, if is a gram neg that does not metabolize nitrate
What is leukocyte esterase and what causes it to be falsely negative on dipstick?
- indirect measure of pyuria
- falsely negative if leukocytes are present in low concentration
What is the definition of pyuria?
- not a uniform definition
- 10 WBC per microL in uncentrifuged urine OR >5 WBC/hfp
What are the most frequent bugs that cause UTIs in kids > 2 months?
- E coli
- Klebsiella
- Enterobacter
- Citrobacter
- Serratia
- Staph saprophyticus (in female teens)
What is the minimum colony count indicative of a UTI with a midstream urine?
> or equal to 10^5 CFU/mL or > or equal to 10^8 CFU/L
What is the minimum colony count indicative of a UTI with a in and out cath urine?
> or equal to 5x 10^4 CFU/mL or > or equal to 5 x 10^7 CFU/L
What is the minimum colony count indicative of a UTI with a suprapubic aspiration urine?
any growth
What route for antibiotics is the first like for febrile UTI in a nontoxic child?
oral
-except in kids 2-3 months of age where some experts recommend starting with IV therapy
What is the best first line PO agent for febrile UTI?
Cefixime 8mg/kg/day as a single dose
What is the best first line IV agent for febrile UTI?
Gentamicin IV (5-7.5mg/kg q24) +/- Ampicillin (200mg/kg/day div q6h) --can use Cefotaxime instead of gent but these are broader spectrum so better to use Gent
What features suggest a complicated UTI?
What is the work up of a kid with suspected complicated UTI and what are you looking for?
- hemodynamically unstable
- elevated creatinine
- bladder or abdominal mass
- poor urine flow
- not improving clinically within 24 hrs
- fever not trending downward within 48h of appropriate abx
-do AUS looking for obstruction or abscess
What are the symptoms of cystitis (lower UTI) and how do you treat it?
- UTI sx without fever; frequency and dysuria
- most common in post pubertal girls
- 2-4 day course of PO abx based on local E coli susceptibilities
When do you do an AUS for kids with first febrile UTI? When do you do it and why?
-age
When do you consider VCUG and what is it used for?
- to diagnose VUR and for assessing the degree of VUR
- do VCUG for kid with second episode febrile UTI or if AUS is suggestive of renal abnormality, obstruction or high grade VUR
What are the risks associated with VCUG?
expensive
exposure to radiation
risk of introducing infection
discomfort for the child
What is a DMSA scan? What is it used for? What are side effects?
- used to diagnose acute pyelonephritis when done during acute illness and to identify renal scars when done months after an acute illness
- involves radiation
- useful when the diagnosis of acute UTI or of repeated UTIs is in doubt
How long should a child with febrile UTI be treated with abx?
7-10 days
Which infants are considered high risk for developing allergy?
-has a first degree relative (at least one parent or sibling) with atopic dermatitis, food allergy, asthma or allergic rhinitis
What foods should you avoid during pregnancy to help prevent allergy in the baby?
none
What foods should be restricted during breastfeeding to help prevent allergy in the baby? Which allergy is there possibly evidence for for restricting maternal diet?
No foods should be restricted but there is the possibility that restriction may help prevent atopic eczema.
When should you introduce allergenic foods (peanuts, fish, eggs, etc)?
- do not delay bc this can actually increase the risk of allergy development
- no convincing evidence to delay introduction beyond 4-6 months
- CPS currently recommends exclusive breastfeeding until 6 months but evidence may change to say ok to introduce earlier
What principles are important when introducing foods such as peanuts, fish, eggs etc to babies?
-early introduction and regular exposure to induce tolerance (several times per week)
If you are choosing a formula for a baby which should you choose to minimize allergy risk?
-hydrolyzed cow’s milk based formula b/c has preventative effect against atopic dermatitis
What is the role for skin testing or specific IgE blood test in infants?
-routine screening without a history of the child ever ingesting the food is discouraged b/c of high risk of potentially confusing false-positive results
What is the latest solid foods should be introduced and why?
- 6 months at the latest b/c delaying it further puts baby at risk for iron deficiency anemia and other micronutrient deficiencies
- introduce iron rich foods first (iron fortified cereal, meat, fish, tofu)
- if delay beyond this consider iron supplementation
What are the 2 types of weaning from the breast?
infant led (usually complete btwn 2-4 yrs) and mother led
What is a nursing strike (breastfeeding) and what are ways to overcome it?
-nursing strike is a sudden temporary refusal to nurse and can result from many causes including infant illness, change in mothers soap, diet, onset of menses etc
- make feeding time special and quiet
- increase cuddling time
- offer breast when babe is very sleepy or just waking up
- offer breast frequently, in different positions, in different rooms
If an infant refuses to take a bottle from the mum after breastfeeding has ceased or is being ceased what are some strategies?
- can offer milk in a cup
- may need to be fed milk or other foods by an alternate caregiver
If abruptly wean breastfeeding what should you counsel the mother?
- take analgesics
- express just enough milk that her breasts feel comfortable
- cold gel packs, cold cabbage leaves or breast massages may relieve engorgement
- watch for signs of a plugged duct (isolated pea sized hard or tender area without local heat) b/c can lead to mastitis
- normal to feel guilt or sadness
For how long should a baby be breastfed?
-exclusively for 6months and continued breastfeeding until 2 yrs and beyond
What are early childhood caries?
- presence of one or more decayed, missing (due to caries) or filled tooth surfaces in any primary tooth in a preschool-aged child
- prevalence in urban areas is 6-8%, up to 90% in some indigenous communities
What are the 4 different ways canadians can pay for dental care?
1) third-party insurance (employment-related)
2) private dental insurance
3) paying out of pocket
4) government subsidized programs (eg. veterans or first nations)
What factors contribute to early childhood caries?
- diet
- bacteria
- host
- social determinants of health
- frequent, prolonged bottle feeding
- excessive juice consumption
- low SES
- new immigrant
- aboriginal or first nations
What measures are there to help prevent early childhood caries?
- fluoridation of water
- promote proper feeding
- dental sealants
- topical fluorides (varnish on teeth you paint on)
Which organism is most associated with early childhood caries?
- Streptococcus mutans
- window for infectivity is btwn 19-31 months of age
Which branch of government is responsible for dental benefits?
provincial/territorial
When should a child first go see a dentist?
between 6-12 months of age
What is the most common type of neonatal hearing loss?
- sensorineural
- genetic cause found in 50%
- 70% have nonsyndromic deafness
What are risk factors for neonatal sensorineural hearing loss?
- FHx of permanent hearing loss
- craniofacial abnormalities including those involving the external ear
- congenital infections (meningitis, CMV, roxo, rubella, herpes, syphilis)
- physical findings consistent with an underlying syndrome associated with hearing loss
- NICU stay >2 days OR with any of ECMO, assisted ventilation, ototoxic drug use, hyperbili requiring exchange transfusion
If not screened at what median age are children diagnosed with hearing loss? With screening was is the age?
- without screening 24 months
- with screening 3 months or younger (intervention by 6 mo)
Parental concern about hearing loss is predictive of true hearing loss. True or False.
True
What are otoacoustic emission (OAE) tests?
What are they useful for?
- sound stimulus sent to newborn’s auditory system via probes put in external ear canal; the probe simultaneously records emissions returning from the outer hair cells of the cochlea via the middle ear
- good for diagnosing hearing loss of 30dB or greater; detects conductive and cochlear hearing loss
What is auditory baronets response (ABR) screening for hearing? What are they useful for?
- sounds are transmitted to infant via earphones and then records brainstem electrical activity in response to the sounds presented to the infant
- can identify conductive, cochlear and neural hearing loss from external ear to level of brainstem including CN VIII
Who should be tested with ABR as opposed to OAE?
- infants who fail the OAE
- infants with risk factors for sensorineural hearing loss
How is newborn screening usually done?
Usually do OAE first and if fail do the ABR
If a child is identified as having hearing loss, who should be involved as part of the team?
- pediatrician
- GP
- audiologist
- ENT
- SLP
- also need prompt vision assessment and referral to geneticist to determine underlying aetiology may be necessary
What is the false positive rate of hearing screening?
2-4%
What are short falls of universal newborn hearing screening programs?
- does not detect less severe congenital hearing loss
- does not detect progressive, or late-onset hearing loss (e.g. from CMV)
Children with cochlear implants have increased risk of meningitis and specific recommendations for preventive vaccination have been made. True or false.
True
A vegetarian diet can provide for the needs of a growing child. True or false.
True if it is well-balanced
What is a lacto-ovo-vegetarian? What is a vegan?
- lacto-ovo-vegetarian - no meat, fish, fowl or products containing these but do eat eggs and dairy.
- vegans - no meat, fish, dairy or eggs - no animal products at all
What adjustments need to be made for protein intake for children who are vegan and why?
increase protein due to lower digestibility of plant protein
What adjustments need to to be made for iron intake in vegetarians and vegans and why?
-increased iron (1.8x intake) b/c of different bioavailability and vitamin c and other components enhance the absorption of nonheme iron
What foods are iron rich?
iron-fortified cereals
grain products (iron-fortified)
dried beans and peas
What part of our diet provides zinc? When do breastfed infants start to need zinc from sources from non-breastmilk?
- 50% of our zinc intake comes from animal protein
- zinc also found in legumes, nuts, yeast-leavened breads, fermented soy
- breastmilk has enough since for infants up to 7 months
- we do not supplement with zinc
What is the effect of a maternal vegan diet on a breast-fed infant’s calcium? What is the effect of vegan diet on a child’s calcium?
- calcium in breastmilk is unaffected by a maternal vegan diet
- many vegan kinds have low calcium levels so may need supplmentation
Which foods are good sources of calcium?
- calcium fortified foods (soy products, cereals, juices, leafy vegetables)
- bok choy
- chinese cabbage
- kale
- collards
Vegan diets are relatively deficient in long-chain omega-3 fatty acids (DHA and EPA) b/c are mostly found in fish, seafood and eggs. What can you tell them to include in their diet to make up for this?
- precursor of linolenic acid which are then converted to EPA and DHA
- flaxseed
- canola oil
- walnuts
- soy products
What deficiency are vegans most at risk for? And what are the implications for children?
- Vitamin B12
- breastfed infants need to be supplemented
- for kids sources of B12 include: fortified soy formula, and cereals, yeasts,
- need 3 servings of Vit B12 rich foods a day or supplement with 5-10 micrograms per day
What is considered adequate sun exposure in a light skinned child for vitamin D?
20-30 minutes 3x/wk
What founds contain vitamin A and how many servings do vegans need to have of these a day?
- yellow and orange vegetables, leafy greens, fruits rich in beta-carotene
- 3 servings of these vegetables and fruits per day
What is the recommended fibre intake a day?
0.5g/kg/day
What is the recommended for vitamin D in pregnant and lactating mums?
2000 IU per day through the winter
What deficiencies are vegans at risk for?
- vit b12
- zinc
- need increased iron
- omega-3-fatty acids (precursors)
- calcium
What is the Greig Health Record?
- evidence-based health supervision guide for clinicians caring for kids age 6 to 17 years
- template for periodic health visits and anticipatory guidance
What % of kinds in Canada are affected by ADHD?
1 in 20 (5%)
What are down sides of prescribing immediate release stimulant medications?
- require repeated doses during the day
- stigma of taking drug at school
- disrupts school routine
- less compliance
- more likely to be sold/diverted and misused
Why do we treat ADHD with medication?
- better academic and social outcomes
- decreases risk of substance abuse if treated
- less likely to visit an ED or be admitted due to injury
What type of stimulant medication should be considered first line for ADHD treatment?
Extended release preparations
A patient with ADHD on treatment is at increased risk for substance abuse. True or false
False
Which is more efficacious in treating the symptoms of ADHD, extended release or immediate release?
-they both work well but it is the abuse potential and repeated dosing etc that makes extended release meds the better choice
What % of kids who have an out-of-hospital arrest survive?
1.9%