GI agents Pharm test 9 Flashcards
dopamine antagonists int and classes
Post Op N/V
CINV
Butyrophenones
Phenothiazines
Metoclopramide
Phenothiazenines (dopamine antagonist
Promethazine (phenergan)
promethazine ADR (phenergan)
Sedation (resp depression)
extreme caution in children and the elderly
IV: tissue injury, access, necrosis, gangrene, amputation
Dopamine antagonist butyrophenos examples and ADR
droperidol
haloperidol
ADR: EPS, sedation, hypotension, prolonged QT
Dopamine antagonists most common ADRs
anticholinergic:
hypotension
sedation
EPS
Dopamine antagonist: metoclopramide
type of agent
Indication
Contraindication
ADR
prokinetic
post op NV or CINV
also diabetic gastroparesis, gerd
increase in motility: GI bleed, obstruction, perforation
ADR: EPS Sedation, diarrhea