Gi Flashcards

1
Q

ph findings in mesenteric ishaemia

A
  • metabolic acidosis
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2
Q

when does mesenteric adenitis typically happen

A
  • after URTI
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3
Q

3 types of mechanical intestinal obstruction

A
  • luminal; gallstones, faeces, foreign body, meconium
  • intra mural; strictures, intussusception
  • extraluminal; hernia, adhesions, volvulus
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4
Q

different symptoms depending on small vs large bowel obstruction

A
Small; 
pain = high frequency colic, central
vomit = early
distention = late
constipated = late

large bowel

  • pain = low frequency colic, lower abdo
  • vomit = late
  • distention = early
  • constipated = early
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5
Q

causes of paralytic intestinal obstruction

A
  • sympathetic activity; reflex post op, rtroperitoneal bleed, malignancy
  • bacteria
  • biochem = k, urea, ca
  • opiates, anticholinergics
  • inflammation
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6
Q

what is considered dialtation in the small bowel

A
  • > 3cm.

- valvulae coneventei all the way round

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7
Q

what is considered dilatation in large bowel

A
  • 6cm +

- haustra not all the wat

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8
Q

what condition do you get the late sign of hiccups

A
  • Peptic ulcer perforation
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9
Q

what glasgow blatchford score do you need to have a high chance of needing an intervention for UGI bleed

A
  • 6+
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10
Q

what score predicts a high risk of death from UGI bleed in the rockall system

A
  • > 8
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11
Q

if a patient has haematemesis due to UGI bleed, where most likely is the problem

A
  • proximal to the duodenal jejunal flexure
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12
Q

what one Warfarin reversal agent do you not give in UGI bleed

A
  • PCC, give FFP and plt instead if needed
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13
Q

what are the ALARMS symptoms

A
  • anaemia
  • loss of weight
  • anorexia
  • recent onset of progressive symptoms
  • Malaena/ haematemesis
  • Swallowing issues
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14
Q

how long before OGD must a patient nto eat

A
  • 6hrs
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15
Q

what kind of cancer does barrets usually become-

A

invasive adenocarcinoma

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16
Q

define short vs logn barretts

A
  • <3cm

- >3cm

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17
Q

surveillance guidance for baretts

A

no dysplasia - 2-5yrs

low grade; 6/12; biopsy every 1cm. radiofrequency ablation

high grade - 3/12. if visible lesion = endoscopic ablation with mucosal resection or radiofrequency ablation / oesophagectomy

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18
Q

typical sx Oesophageal ca

A
  • dysphagia progress from solids to liquids
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19
Q

symptoms of diffuse oesophageal spasm

A
  • intermittent dysphagia +/- chest pain
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20
Q

what is the mechanism behindd achalasia

A
  • degeneration of myenteric plexus stopping the LES from relaxing
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21
Q

sx achalasia

A
  • dysphagia
  • regurg
  • weight loss
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22
Q

rx achalasia

A
  • endoscopic baloon dilatation
  • hellers cardiomyotomy

then PPI
0r

Botox if no surgery

CCB and nitrates also relax sphincter

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23
Q

plummer vinson sydrome triad

A
  • oesephageal webs
  • IDA
  • post cricoid dysphagia
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24
Q

which type of oesophageal ca is HPV a RF for

A
  • squamous
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25
what are you doing in a iv lewis oesophagectomy
- right sided thoractomy - stomach into chest and oesophagus division mobilised - anastamosis = intrathoracic oesophagogastric
26
what is zollinger ellison syndrome
- pancreatic or gastric gastrin secreting tumour
27
zollinger ellison syndrom sx
- abdo pain, dyspepsia, chornic diarrhoea and steatoorhea due to inactivation of pancreatic enzymes and damaged intestinal mucosa
28
zollinger ellison syndrom ix
- fastign gastrin level in serum . 3 x 3 days | - hypochlorhydria = reduced acid production will also cause increased gastrin production - ph will be <2
29
zollinger ellison syndrome rx
- high dose PPI | - surgery unless MEN1 = multiple adn mets #- somatosatin analogue and chemo
30
what type of ab is produced in h pylori
igg
31
screening test for h pylori and instructions
- urea breath test; stop abx 4 weeks before and PPis 2 weeks before
32
what does NICE recommend for gastric ulcers
all to biopsy as high malignant potential
33
rf gastric ca
- h pylori - smoking - alcholo - diet high in nitrates - EBV; diffuse type - autoimmune gastritis - e cadherin mutation = diffuse type. fhx - FAP - intestinal type
34
two types of gastric adenoca
- diffuse = worse prognosis, young people. signet cells | - intestinal - old - better prognosis
35
where does gastric ca spread to
- Lymph | - lungs, liver, brain, ovaries via transcoelemic
36
rx gastric ca
- <5cm to OG jnct - total gastrectomy - 5-10cm from jnct = sub total gastrctomy +/- ESSMR + d2 NODAL RESECTION + chemo
37
name the 3 types of surgery that can be done for gastric ca
- bilroth 1 - bilroth 2 - roux en y
38
what is bilroth one surgery
- partial gastrectomy with simple anastamosis
39
what is bilroth 2 surgery
- partial gastrectomy wtih duodenal stump oversewn and anastamosis in jejunum
40
roux en y
- total or partial - proximal duodenum oversewn - proximal jejunum divided from distal - proximal jejunum connects to oesophagus - - distal duodenum connects to jejunum
41
what is mirizzi syndrome
- compression of common bile duct by stone impacted in cystic duct
42
what can present similarly to jaundice
- hypercarotenaemial after prolonged and excess consumption of foods containing carotene
43
how to treat ascending cholangitis
ERCP
44
which anaesthetic can cause jaundice
- halothane
45
what liver problem is xanthelesmata a indication of
- primary biliary cirrhosis
46
what happens to colour of urine in hepatic jaundice
- darker as conjugated bilirubin is excreted by the kidney
47
what happens t o colour of urine and stools in post hepatic jaundice
- dark urine | - pale stool
48
common drugst that cause cholestatic jaundice
- fluclox - steroids; cocp, anabolic - sulfonylureas - prochloperazin r - chlorpromazine
49
where is hep a an endemic
- south america and africa
50
incubation period of hep a
2-6 weeks
51
what type of vaccine is available for hep a and who gets it
- inactivated = havrix monodose - at risk; travellers tp endemic areas, close contacts, chronic liver disease, blood clotting disorders, MSM, IVDU, Occupational, HIV
52
hep b incubation period
- 1-6 months
53
what bone issue do patients with hep a and b get
- arthralgia
54
what does antihbs indicate
- previous immunisation or exposure
55
what does hbsag indicate
- current infection
56
what does anti hbcag indicate
- past infection | - sometimes current
57
what does hbeag indicate
- infectivity
58
complications of hep b infection
- chronic; ground glass hepatocytes on microscopy - HCC - cryoglobulinaemia - polyarteritis nodosa - glomerulonephritis - fulminant liver failure
59
when are kids immunised for hep b
2,3,4 minths
60
what do the following anti-Hbs levels mean post immunisation 1. >100 2. 10-100 3. <10
1. adequate response, no more test. booster at 5yrs 2. suboptimal response. 1 more dose. if immunocompetent then no further tests needed 3. non responser. test for current or past infection. give course of 3 vaccinations and testing after.
61
rx hep b
- pegylated interferon 1st | - tenofovir 2nd
62
hep c incubation period
- 6-9 weeks
63
can you breastfeed if you have hep b/c
yes
64
hep c ix
- HCV RNA
65
hep c complications if chronic
- arthralgia, arthritis - sjogrens - HCC, Cirrhosis - cryoglobulinaemia - porphyria cutanea tarda esp with alcohol abuse - membranoproliferative glomerulonephritis
66
what is porphyria cutanea tarda
- blistering skin on sun exposure
67
rx hep c acute
- support
68
rx hep c chronic
- test viral genotype | - protease inhibitor +/- ribavarin
69
ribavarin SE
- Cough, haemolytic anaemia. teratogen. cotnraception till 6 months after stopping
70
hep d ix and rx
= anti hdv if hbsag present - INF alpha
71
what should babies born from hep c/b positive mums have
- full course vaccien + ig
72
2 types of autoimmune hepatitis
- 1 = 80%, young and middle aged. anti - SMA +ve, 10% ANA +Ve. IgG raised - Type 2 - anti-LKM1 +ve . ana and asma -ve kids and europe
73
rx autoimmune hepatitis
- prednisolone - azathiprime for maintenance from remission usually in 2-3 yrs - transplant
74
what is the classification system for encephalopathy
- west haven
75
west haven classificaiton of encephalopathy grades
1. sleep reversasl, lack of awareness, short attention span, impaired computations 2. lethargy, memory impaired, personality change, asterixis 3. somnolence, confused, disorientated. hyper-reflexia, nystagmuus, clonus, rigidity 4. stupor/ coma
76
rx encephalopathy
lacutlose rifaximin as prophylaxis
77
indicators of poor prognosis in acute liver failure that is paracetemol induced
- ph 7.3 or - INR >6.5/ PT >100seconds - grade 3/4 encephalopathy - creat >300 - lactate >£
78
indicators of poor prognosis in acute liver failure that is NOT paracetemol induced (also kings college criteria for transplant)
- Ph <7.3 post volume resus - PT >100 s ``` or 3 of beloow - PT >50 (INR >3.5) - Bili >300 - jaundice to enceph >7/7 - age <10/ >40 - etiology; NANB (non hep a , non hep b) or drug induced ```
79
if acute liver failure and hepatic encephalopathy + cerebral oedema - RX
- Mannitol | - hyperventilate
80
5 stages of cirrhosis
1. no varices 2. varces decompensated 3. bleed 4. ascites 5. ascites bleeding
81
what metabolic issues canc ause decompensated liver failure
- hypokalaemia as causes ammonia to build up and cross BBB - metabolic alkalosis - increased protein intake = more ammonia - constipation - prolonged exposure of GI content
82
RF for Alcoholic liver disease
- alcohol - hep c - female - obese
83
what happens to plt in liver disease
- goes down due to splenic sequestration
84
what happens to na in liver disease
- down in cirrhosis
85
what happens to ast:alt ratio in cirrhosis
- >1
86
what scoring system predicts prognosis in chronic liver disease
- child pugh
87
what is the minimum score on UKELD to be added to transplant list for liver
- 49
88
transudate causes of ascite s= low protein
- cardiac failure - liver failure - nephrotic syndrome - myxoedema
89
exudate causes of ascites = high protein
- cirrhosis - abdo malignancy - pancreatitis - infection/ TB/perforation - lymphatic obstruction
90
ix for someone with ascites
- FBC, = infection - u and e = renal failure - LFT - CLotting - TFT - hepatitis screen - amylase - USS/CT - Ascitic tap + mc&s, cytology and biochem
91
rx ascitic liver disease-
salt restrict - spironolactone 1st line - furosemide 2nd - paracentesis + fluid replace - TIPS
92
what does alt>ast indicate in terms of NASH/NAFLD
-NASH
93
what does steatosis mean
- fat in the liver
94
what does steatohepatitis mean
- fat with inflammation --> NASH
95
ix for NAFLD
- If incidental found on liver uss --> enhanced liver fibrosis blood test. if unavailable fib4 score and fibroscan - liver biopsy for staging
96
most common type of pancreatic cancer
- adenocarcinoma
97
rf pancreatic cancer
= smoking
98
what is the only curative surgery in pancreatic ca
- whipples procedure | - remove distal stomach, gallbladder, common bile duct, head of pancreas,e duodenum, proximal jejunum and regional LN
99
rare features of pancreatic ca
- thrombophlebitis migricans = arm vein swells thena leg one - high ca - endocarditis - portal HTN = splenic vein thrombosis - nephrosis. renal vein mets
100
sx of body of pancreas ca
- back pain - steatorrhoea - weight loss - anorexia - abdo pain relieved by sitting forward
101
sx of tail of the pancrease ca
- late presentation with mets, malignant ascites or unexplained anaemia
102
define acute diarrhoea
- <14 days
103
define chronic diarrhoea
- >30 days
104
4 types of diarrhoea
- osmotic - secretory - infectious.infla - deranged motility
105
What happens in osmotic diarrhoea
- food is staying in intestine so drawing more water in
106
what causes secretoroy diarrhoea
- cholera - laxatives - hormones from tumours
107
extra intestinal manifestations of UC
- Ank spond - osteoporosis - osteopenia - uveitis - episcleritis - conjunctivitis - erythema nodosum - pyoderma gangrenosum
108
crypt abscesses are a typical feature of which type of IBD
- UC
109
classify severity of UC
- Mild = <4 stools passed, only little blood - moderate 4-6 stools, moderate varied amount of blood, no systemic upset - severe - >6 bloody stools pr day + systemic upset
110
UC treatment
induce remission; mild/moderate - topical salicylate - no improvement in 4/52 --> oral ASA, then if doesnt work then oral steroids severe --> IV steroids/ ciclosporin if steroid CI maintain - mild/mod and proctitis = topical asa or topical and oral asa - mild/mode and left sided or extensive = oral ASA severe or more than 2+ relapses in a year = azathioprine
111
rx crohns disease
induce; steroids or budesonide if CI +/- enteral feed 5-ASA 2nd line ``` maintain - stop smoking azathiprine/ mercapto - 2nd = methotrexate - 3rd - ASA ``` surgery; ileocaecal resection right hemicolectomy hartmanns I and D with seton
112
UC surgery options
- total coelectomy with - ileo anal anastamosis - ileall pouch - end ileostomy - sub total colectomy
113
what nutritional deficiency do patients with crohsn often have
- b12 and folate
114
p ANCA is more often found in which type of IBD
- UC
115
determining severeity of UC is classified by which system
- true love and whitts criteria
116
thumb printing, lead pipe and toxic megacolon are common in which type of IBD
- UC
117
apple core strictures are seen in which type of IBD
- Crohns
118
contraindications to liver biopsy patients
- uncooperative patient - bacterial cholangitis - coagulopathy
119
what size liver HCC can be resected
- <5cm | - or up to 3 lesions <3cm
120
what cells are affected in carcinoid syndrome
- enterochromaffin
121
what are cardiac complications of carcinoid syndrome
- pulmonary stenosis | - tricuspid incompetence
122
ix and rx carcinoid syndrome
- High 5-IHIAA in urine rx - somatostatin analogue
123
cholangiocarcinoma causes
- flukes | - primary sclerosing cholangitis, hep
124
cholangiocarcinoma rx
- major hepatectomy + extrahepatic bile duct excision + caudate lobe resection. - post op comp = bile leak, liver failure and obstructed extrahepatic biliary tree - fix with ERCP
125
liver adenomas are associated with what rf
- cocp | - anabolic steroids
126
when to treat liver adenoma and how
- if sympto or >5cm - stop cocp - resect
127
abx for amoebic liver abscess
- metronidazole
128
what liver issue can cause a pleural effusion in the right lower zone
- liver abscess
129
what bone issue does hereditary haemochromatosis cause
- chondrocalcinosis
130
incubation period noro
- 24-48hrs
131
incubation period of staph and abcillus
- 1-6hrs
132
incubation period of salmonella and ecoli
12-48hrs
133
incubation period shigella and campylobacter
- 48-72hrs
134
incubation period giardiasis and amoeibasis
- >7/7
135
ix gastroperesis
- scintigraphy - >10% retention after 4hrs of meal
136
rx gastroperesis
- prokinetic e.g. metoclopramide | - antidepressant
137
IBS diagnostic criteria`
- recurrent abdo pain at least 3 days/month for 3months with 2 or more of the following - relief on defecation - onset assocaited with change in frequency of stool - onset associated with change in form/áppearance of stool
138
which types of polyps are higher risk of colon cancer
= villous
139
what is the mechanism of cancer in FAP-
- germline mutation in APC gene - chromosome instability pathway.
140
inheritance pattern of FAP
- AD
141
Why do we do prophylactic panproctocolectomy in FAP patients
- 100% get colon adenocarcinoma by 40. have many polyps and every single cell in body already has mutation so only needs one more hit for cancer.
142
cancers more common in FAP-
- Colorectal; small intestine - gastric cancer - desmoid tumours - thyroid cancers - osteomas - RPE congenital hyeprtrophy
143
lynch syndrome MOA and inheritance pattern
- microsatellite instability pathway; mismatch repair genes mutations - one allele of MSH6, MSH2, MLH1, PMS2
144
cancers more common in lynch syndrome
colorectal - endometrial - stomach - pancreas - small bowel - ureter - renal pelvis - ovarian cancer
145
what side of colon to lynch syndrome cancers appear
- right side
146
what is constipation defined as
- <2 motion/week - less than normal - difficult/ incomplete evacuation
147
what metabolic abnormalities can cause constipation
- hyperca - hypothyroid - hypok - porphyria - lead poisoning - T2DM
148
what common drugs given in HTN cause constipation-
CCB | Diuretics
149
other name for lynch syndrome
- HNPCC
150
dukes criteria staging
A = mucosa, submucosa +/- muscularis propria B = subserosa and beyond C = Any with LN involved D = distant mets
151
what surgery do you do for rectal tumours
- anterior resection = remove all rectum with primary anastamosis - abdomino perineal resection = if tumour low in rectum <8cm from anus = remove rectum and anus and permanent colostomy - total mesorectal excision
152
all surgical resections of colon require hwo many cm clearance
5cm
153
which side of colon are hyperplastic polyps usually seen? what about sessile?
left right
154
what do alpha cells in pancreas make
- glucagon
155
what do delta cells in the pancreas make
- somatostatin - supresses release of gastric hormones so decreased rate of gastric emptying
156
why does calcium rise cause pancreatitis
- activates conversion of trypsinogen to trypsin --> autodigestion
157
complications of acute pancreatitis
- shock - aki - ards - DIC - Sepsis
158
modified glasgow criteria for pancreatitis
``` Pao2 <8 Age >55 N = WCC>15 C = calcium <2 Renal= urea >16 Enzymes = LDH >600/ AST>200 A = albumin <32 S= sugar >10 ``` 1 point if any criteria in first 48h. 3+ = ITU
159
rx acute pancreatitis
- fluid resus - ng tube to decompress - analgesia - not morphine if possible - antiemetic - sort glucose - vitals - ERCP if gallstones
160
what skin issue can you get in chronic pancreatitis
- erythem ab igne
161
what type of DM does chronic pacnratitis cause
- type 3c; disease of exocrine pancreas
162
cause of acute mesenteric ischaemia
- embolus, thrombus, non occlusive ischaemia
163
cause of chronic mesenteric ischaemia
- atherosclerosis of all 3 vessels supplying the gut
164
sx acute mesenteric ischeamie
- abdo pain - no abdo sign - shock
165
sx chronic mesenteric ischaemia
- severe colicky post prandial pain = gut claudication - pr bleed - weight loss - feaer of food - malabsoprtion - fatigue - abdo bruits - abdo tender
166
sx chronic large bowel ischaemia
- bloody diarrhoea - left sided abdo pain - fever - tachy - PR blood
167
what is the colalteral blood supply to the colon
- marginal artery of drummond
168
watershed zones in the colon vulnerable to mesenteric ischaemia
- right colon as artery of drummon not well developed here. - splenic flexure as tenuous or missing artery of drummond - rectosigmoid junction as distal to last collateral of proximal arteries that supply colon
169
most common organ involved in stabbings
- liver
170
organ most commonly involved in gunshot wounds
small bowel
171
indications for resus laparotomy in abdo trauma
- life threatening blunt trauma | - unresponsive hypotension despite resus with no other cause of bleeding found
172
indications for urgent laparotomy in abdo trauma
- blunt trauma with positive lavage or free blood on USS with unstable circulation - peritonitic - kinfe injury associated with visible viscera, peritonitis, haemodynamic instability or sepsis - gunshot wound
173
what is choledocholithasis
- gallstone obstruct common bile duct
174
what is gallstone ileus
- obstruction of small bowel by gall stone via fistula. the obstruction causes vigorous peristalsis = gallstone ileus (different to what ileus normally means)
175
in which gallstone related disease would you do a U and E and G and s as well as clotting and ABG
- ascending cholangitis
176
who are spigelian hernias most commonly seen in, and what are they called
- older pts - lateral ventral; hernia through spigelian fascia (the aponeurosis between the rectus abdominas medially annd the semilunar line laterally
177
what is a richters hernia
- only antimesenteric border of the bowel herniates through the fascial defect
178
congenital inguinal hernias are more common on which side
- right
179
where are inguinal hernias in relation to the pubic tubercle
- medial and above
180
direct vs indirect hernia relationship to inferior epigastric artery
- medial = direct | - lateral = indirect
181
direct hernia rx
- open mesh/ lap | - wait and watch
182
indirect hernia rx
- kids = herniotomy, adults = open mesh/lap | - wait and warch
183
inarcerated femoral hernia operation
= iguinal approach | if not incarcerated and not small bowel involved can do infrainguinal
184
where do femoral hernias lie in relation to femoral vein
- medial
185
how to treat incisional hernias
- <4cm = simple sutures - >4cm = place mesh between posterior rectus sheath and rectus abdominis - lap approach
186
what is zenkers divcerticulum
- pharyngoesophageal false diverticulum. oesophageal dysmotility = herniation of mucosa at killians triangle b/ween thyro and cricopharyngeal constrictor
187
sx of zenkers diverticulum
- dysphagia - obstruction - gargling - halitosis - neck mass - aspiration
188
zenkers diverticulum mnemonic
- elder mike has bad breath - elderly people - killian triangle - halitosis - oesophageal dymsotility
189
what are the rule of 2s for meckels diverticulum
- 2 times more common in men - 2 inches long - 2ft from IC valve - 2% population - common presents in first 2yrs of life - 2 types of epithelia; gastric/pancratic
190
staging for surgery or not in diverticular disease (hinchey classification)
stage 0 = no abscess stage 1; pericolic or mesenteric abscess = no surgery - radiological drain 2 = walled off or pevic abscess = sometimes surgery - lap washout/radio drain 3= generalised purulent peritonitis = surgery - wash out/ hartmanns 4= generalised faecal peritonitis = surgery - hartmanns
191
pus somewhere pus nowhere in context of asbcess means...
- pus under diaphragm
192
what abx do we most commonly give in acute diverticulitis
- cipro | - metro
193
where do far eastern people get diverticulitis
- right side
194
appendicitis GS dx
- CT
195
what is the scoring system used in appendicitis
- alvadaro score >7 = appendicitis - <5 - unlikely - RIF tenderness 2 - rebound tenderness 1 - rif migratory pain 1 - anorexia 1 - n and v 1 - fevver 1 - leukocytosis 2 - left shift neutrophils 1
196
what incision is used in open appindectomy
- grid iron
197
why do you never make a lateral incision at mcburneys point in appindectomy
- can cut ileohypogastric nerve
198
main RF for cholangiocarcinoma
- Primary sclerosing cholangitis - liver flukes - typhoid
199
anal cushion positions
- 3,7, 11 oclock
200
where does lymph drainage above the pectinate line occur | - below?
- pelvic | - inguinal
201
classification of haemorrhoids
1. remains in rectum 2. prolapses through anus on defecation but reduces spontaneously 3. protrudes throught anus but needs digital reduction 4. remain persistently prolapsed OR INTERNAL VS external - pectinate line seperates
202
surgical rx for haemorrhoids and there associated side effects
- band ligation - banding = ulcer tethering mucosa. SE = Bleed, pain, infection - sclerotherapy; SE = Impotence, prostatitis - infra red photocoag - surgical removal in grade 4 and where other options failed. SE - Haemorrhage and stenosis. 2 weeks off work needed.
203
anal fissure rx
- conservative - lidocaine for topical pain relief - GTN ointment - diltiazem - botox - lateral sphincterotomy
204
what is goodsalls law for fistula in ano
- anterior fistula = vertical drain | - posterior drain at 6o clock
205
anal abscess classification
- intersphincteric = in between internal and externals phoncter - perirectal = ischiorectal psace - supralevator = above anorectal ring
206
parks classification of anal fistulas
- intersphincteric - transphincteric ; through external sphincter - suprasphoncter - ascends from intersphinceteric space to puborectalis then levator ani - extrasphinceric - outside external sphinc
207
fistula rx
- fistulotomy and excise | - seton suture esp if high fistula where excising = incontinence
208
what kind of cancer is anal ca most commonly
- SCC
209
what type of anal cancer has worse prognosis
- above pectinate line is worse
210
rx anal ca
- chemo and radio = preferred | - AP resection if failed after 6 weeks of CHRT
211
rx rectal prolapse
- manual reduction or if persists - abdo approach = rectopexy +/- mesh +/- rectosigmoidoscopy - perineal approach - delornes procedure = resect close to dentate and sutture muscosal boundries
212
causes of b1 defi and sx
- alcoholics or white rice diet | - polyneuropathy, HF, Wernickes
213
causes of B2 def
- decreased milk or chronic malabsoprtion
214
B3 deficiency causes
- Dermatitis - diarrhoea - dementia - -> v photosensitive
215
sx vit c deficiency
- gingivitis, petechiae, rash, internal bleeds, impaired wound healing - need for bone and bvs
216
rx for morbid obesity
conservative medical ; orlistat if BMI >30 or >28 + RF. Max 1 yr use surgical if BMI >40 OR 35+ with comorbidities and failure of diet measures - gastric banding - bypass - sleeve gastrectomy; remove part of stomach - intra gastric ballooon -- filled with air or salt water then passed downt throat - biliopancratic diversion