breast Flashcards

1
Q

which two cancers are the BRCA genes associated with

A
  • breast

- ovary

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2
Q

pagets disease of breast is what type of cancer

A

DCIS

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3
Q

in lobular carcinoma what is the hisotological appearance and why

A
  • loss of e cadherin - seperates cells
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4
Q

3 genomic classification types of breast ca

A
  • luminal type a and b; a better prognosis than b. usually low grade. ER +Ve her2 -ve
  • her 2positive
  • basal like - high grade er-ve, her2 -ve
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5
Q

how big does a fibroadenoma need to be to offer excision

A

> 25mm

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6
Q

what is the scoring system for breast lump reporting

A

BIRADS

  • exam SCORE
  • Imaging SCORE
  • Biopsy score
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