GI Flashcards
hemochromatosis diagnosis
treat with
elevated transferrin sat, ferritin>1000
phlebotomy
chronic diarrhea 2/2 malabsorption of artificial sweeteners
diarrhea, bloating, elevated osmotic gap
SAAG 1.1 or greater+ ascitic protein of 2.5 or greater
cirrhosis/portal htn
cardiac cause of ascites
ascitic protein <2.5
SBP treatment
3rd gen cephalosporin and albumin (1.5g/kg on day of diagnosis, 1g/kg on day 3)
dyspepsia + alarm features
age>50 yo, anemia, dysphagia, odynophagia, vomiting, weight loss, family history of cancer, PUD, gastric surgery->scope
No alarm features, endemic h. pylori
not endemic h. pylori
partial response to PPI
if still refractory with normal scope
test for h. pylori, treat
PPI
increase dose to twice daily
ph monitoring->fundoplication
AKI in the setting of cirrhosis
25% albumin challenge, then midodrine and octreotide (rule out ATN with urinalysis first)
ulcer with arterial spurting or a nonbleeding visible vessel
clips, thermal therapy or sclerosants
clean based ulcers don’t need to be treated
primary sclerosing cholangitis
diagnosis
look for
ANA, anti-smooth muscle
MRCP-beads on a string
ulcerative colitis (colonoscopy)
chronic NSAID use
start omeprazole 20mg or misoprostol
chronic pancreatitis
clinical features (pain, recurrent attacks of pancreatitis, weight loss) with objective findings of steatorrhea and pancreatic calcifications
chronic diarrhea, abdominal pain, and malabsorption
confirm with
test for celiac with tissue transglutaminase antibodies
small bowel biopsy: intraepithelial lymphocytosis, crypt hyperplasia, and villous blunting
also elevated LFTs
irritable bowel syndrome studies
no testing/imaging/procedures
unexplained liver disease in patient <40 yo (+hemolytic anemia)
screen
diagnosis
consider Wilson disease
low alk phos, elevated ASTs
low ceruloplasmin , elevated urine copper excretion
liver biopsy
Budd-chiari
ascites
gallbladder polyp> 1cm
any polyp+ symptomatic OR PSC OR gallstones
cholecystectomy
chole
pancreatitis + presence of gallstones (obstructing or not, cholecystitis or not)
chole
Crohns flare while preggo
certolizumab (preferred), infliximab, adalimumab (anti-TNF agents)
5-aminosalicylates for UC, not Crohns
functional dyspepsia
treatment
epigastric pain/discomfort, postprandial fullness, and/or early satiety in the absence of a structural explanation
treat h. pylori/ ppi/ ranitidine->TCA
nonalcoholic fatty liver disease treatment
weight loss
surveillance is necessary only when cirrhosis is present
IBD (UC/Crohns) surveillance colonoscopy
PSC+ IBD
every 1 to 2 years beginning after 8 to 10 years of disease.
as soon as PSC diagnosis is made
large (≥10 mm) or dysplastic sessile serrated polyps or traditional serrated adenomas, repeat colonoscopy in
an adenoma 10 mm or larger, (2) three to ten adenomas, (3) an adenoma with a villous component or high grade dysplasia
> 20mm polyp/ removed in pieces
3 years
3 years
3-6 months
calcified asymptomatic incidental gallstones
observe
chronic diarrhea+ exposure to young kids/ water
giardia (O &P)
type 1 autoimmune pancreatitis
treatment
imaging features (focal pancreatic enlargement with a featureless rim and a nondilated pancreatic duct), increased serum IgG4 level, and extrapancreatic organ involvement (sclerosing cholangitis or IgG4-associated cholangitis) steroids
GI bleed with neg EGD/colonoscopy OR pos capsule
endoscopy
push enteroscopy
IBS with constipation treatment
IBS diarrhea
fiber->polyethylene glycol->linaclotide, Lubiprostone
rifaximin