Endocrine Flashcards
Preggo hyperthyroid
PTU, not methimazole
MEN 2A
MEN 2B
MEN 1
MTC, hyperpara, pheo
MTC, pheo, ganglioneuromas
MTC, hyperpara, GI tumors
preggo prolactinoma
only dangerous with expansion or hypogonadism
so formal visual field testing q trimester
bedtime normal glucose with morning hyperglycemia
obtain 3 AM glucose
Diagnose Cushing’s
Cushing vs ectopic ACTH
2 of these: 1 mg dexa suppression/ 24 hour urinary cortisol/ salivary cortisol. FYI, get screening DEXA
8mg dexa suppression test
switching from insulin to orals in type ii DM
have to ensure beta cell function and no autoimmunity
test for antibodies and fasting c peptide and glucose
pituitary apoplexy and vision loss
steroids and urgent transsphenoidal decompression
thyroid nodule >1 cm
FNA
surveillance post thyroidectomy
TSH
Hypercalcemia
severe: AMS or AKI or >18->hemodialysis, then calcitonin or IV bisphosphonate
PCOS vs late onset CAH
Elevated LH
Bisphosphonate drug holiday
If progressive BMD
stable BMD
only if stable BMD+ therapy for 3-5 years+ minimal risk factors for fractures
teriparatide
Change less than 4%
hyperaldosteronism due to bilateral adrenal hyperplasia
spirinolactone/ amiloride
hyperprolactinemia in setting of hypothyroidism
hypothyroidism causes hyperprolactinemia
treat hypothyroidism first
congenital bilateral absence of vas deferens causes
associated with
klinefelter
obstructive azospermia
cystic fibrosis
primary hypogonadism, 47XXY
Early morning cortisol <3
Stim test indicated only when
Adrenal insufficiency. period. treat
AM cortisol is 4-12 (normal is response >20)
PCOS infertility
clomiphene, then IVF
Microprolactinoma in asymptomatic postmenopausal woman
surveillance: retest in 6-12 months
DM neuropathy treatment
No TCA if cardiac disease, duloxetine instead
Postprandial hypoglycemia (w/in 5 hours of meal) symptomatic fasting hypoglycemia
mixed meal testing
72 hour fast, hypoglycemic testing
Asherman syndrome
diagnosis
amenorrhea+ cyclic pelvic pain post uterine instrumentation
transvag U/S, hysterosalpingogram