GI Flashcards
Define esophageal atresia
Blind esophageal pouch w/ or w/o a fistulous connection between the proximal or distal esophagus & trachea
esophageal atresia clinical presentation
- Copious secretions
- Choking
- Cyanosis & respiratory distress
Trachoeoesophageal fistula distal to esophagus CXR findings
Gas present in bowel
EA WITHOUT fistula CXR findings
NO gas in bowel
EA treatment
- NG tube in proximal pouch on low intermittent suction
- Elevate head of bed to prevent reflux
- IV glucose
- Fluids & O2
- Surgery
Esophageal FB clinical presentation
- Asx=50%
- Dysphagia, odynophagia
- Drooling
- Chest or abdominal pain
What is the MC FB ingested?
Coin ingestion
Define GER
- Uncomplicated recurrent spitting & vomiting
2. Resolves spontaneously
Define GERD
Reflux causes 2ry sx’s or complications:
- Aspiration
- Pneumonia
- Failure to thrive
- GI bleeding
- Food refusal
What is the MC infant sx?
GER
GERD treatment
- Thickening feeds w/ oat cereal
- Milk free (& soy free) diet x 2wks.
- H2 blocker vs. PPI
- Surgery: Nissen Fundoplication (severe)
*reflux resolves spontaneously in 85% of affected infants by 12mo of age
What are the two MC complications of eosinophilic esophagitis (EoE)?
- esophageal food impactions
2. esophageal stricture
EoE si/sx’s
- Feeding dysfxn
- Vague non-specific GERD sx’s
- Long meal times: washing down food w/ liquids
- Avoidance of highly textured foods
- No response to medical &/or surgical GERD tx
- FH or PMH of atopy, asthma
EGD findings in EoE
- Esophageal mucosa w/ thickening, mucosal fissures, strictures & rings
- Esophagus sprinkled w/ white exudates=resembles candida
EoE treatment
- Elimination of food allergens
2. Swallowed topical steroids: Fluticasone
Define Pica
- Persistent eating of nonnutritive substance:Clay, Dirt, Hairballs, Ice, Paint
- Present @ least 1 month
- Inappropriate to developmental level
What is Pica associated with?
Iron and zinc deficiency
Pica treatment
- Address nutrient deficiency or lead poisoning
2. Behavioral therapy & family education
Define Rumination
- Repeated regurgitation and re-chewing of food
- At least 1 month
- More common 3 to 12 months
What is the MC inborn error of amino acid metabolism?
Phenylketonuira (PKU)
Define Phenylketonuira (PKU)
Autosomal recessive
Decreased activity of phenylalanine hydroxylase
What is the MC si/sx in Phenylketonuira (PKU)? 2nd MC?
Intellectual disability=MC
Epilepsy=50%
What race is Phenylketonuira (PKU) MC in?
Caucasians
Phenylketonuira (PKU) treatment
- Dietary restriction of phenylalanine and aspartame
- Tyrosine supplementation
- Elimination of all high-protein foods: meat, dairy, nuts, legumes
- Restrict starches
What is the MC food allergy?
Cow’s milk
What is the MC si/sx in food allergies?
- Urticaria
2. Angioedema
Food allergy treatment
- Avoidance and re-introduction annually
- Epinephrine
- H1 blockers
Define celiac disease
Immune mediated enteropathy triggered by gluten: Protein in what, rye and barley
RF’s for celiac disease
- Type 1 diabetes
- Down syndrome
- Turner syndrome
- Autoimmune thyroidititis
- Family hx of CD
GI manifestations in celiac dz
- Poor weight gain
- Chronic diarrhea
- Abd distention
- Irritability
- Anorexia
- Vomiting
*usually between 6-24mo of age (when gluten 1st introduced)
Non GI manifestations in celiac dz
- Delayed puberty/short stature
- Delayed menarche
- Unexplained Fe def anemia*
Celiac Dz diagnosis
serology &/or duodenal biopsy: villous atrophy w/ increased intraepithelial lymphocytes
Define omphalocele
Membrane covered herniation of the abdominal contents into the base of the umbilical cord
Who is omphalocele MC in?
- Mom’s of extreme maternal age: <20 or >40
2. Associated w/ chromosomal abnormalities
Define gastroschisis
Uncovered (no sac) intestine through small abdominal wall defect to the right of the umbilical cord
What environmental factors are associated with gastroschisis?
- illicit drugs: meth & cocaine
- link w/ aspirin & ibuprofen use during pregnancy
- Young maternal age
Define reducible hernia
Spontaneous or manual
Define incarcerated hernia
Not reducible
NO vascular compromise
Define strangulated hernia
Vascular compromise
What is the MC side in a diaphragmatic hernia
Left
What is diaphragmatic hernia associated with?
Polyhydramnios(excess amniotic fluid)= 50%
diaphragmatic hernia si/sx
- Respiratory distress
- Scaphoid abdomen, barrel-shaped chest
- Signs of pneumothorax: decreased BS on ipsilateral side
CXR findings in diaphragmatic hernia
bowel loops seen in chest w/ mediastinal shift to opposite side
diaphragmatic hernia treatment
- Intubation, mechanical ventilation & decompression of the GI tract w/ OG tube
- Surgery
What is the MC long term complication of diaphragmatic hernia?
Pulmonary HTN
what hernia is the MC in children?
Indirect hernia
Indirect hernia anatomical location
- Passes LATERAL to deep epigastric vessels
- Passes IN the Inguinal canal
- MCly Right sided
Direct hernia anatomical location
- Passes MEDIAL and INFERIOR to deep epigastric vessels
- does NOT go through inguinal canal
- RARE in children
What are the boundaries of the Hesselbach Triangle?
Laterally inferior epigastric artery
Medially lateral border of rectus abdomens
Inferiorly (base) inguinal ligament
What are the complications of femoral hernias? Who is MC in?
MC=Females
Frequently become incarcerated or strangulated
Who are umbilical hernias MC in?
full term, African American infants
Who is pyloric stenosis MC in?
- Males
- First born children
- Whites
Pyloric stenosis si/sx
- Projectile postprandial vomiting
- “Hungry vomiter”
- Oliver mass in RUQ=Hallmark sign*
Pyloric stenosis diagnosis?
Abdominal (Pyloric) US: hypoechoic muscle ring >4mm thickness w/ a hyperdense center & a pyloric channel length
Barium Upper GI finding in Pyloric Stenosis
Apple core or String Sign: long, narrow pyloric canal w/ a double track of barium
Pyloric stenosis treatment
Surgical: pyloromyotomy
What is duodenal atresia associated with?
Trisomy 21
Abdominal x-ray findings in duodenal atresia
Double-bubble sign: Dilated stomach & proximal duodenum
duodenal atresia si/sx
Bilious vomiting hours after birth
duodenal atresia treatment
surgical
What is the main goal of short bowel syndrome?
Promote growth-Many treatment options
What is the MC cause of bowel obstruction in the first 2 yrs of life?
Intussusception
What it the MC location of Intussusception?
starts just proximal to ileocecal valve
What is the MC cause for Intussusception in children >6?
Lymphoma
Intussusception si/sx’s
- Cramping abd pain, diarrhea
- “Red current jelly”: pathognomonic
- Palpable right-sided sausage-shaped mass
X-ray findings in Intussusception
“target sign”: 2 concentric radiolucent circles superimposed
What is the most sensitive and specific diagnostic modality in Intussusception?
US
What is both diagnostic and therapeutic with Intussusception?
Barium & air enema
What is another name for Hirschsprung dz?
Congenital aganglionic megacolon
What is the MC chromosomal abnormality associated w/ Hirschsprung disease?
Down syndrome
Hirschsprung disease si/sx
Usually presents in infancy:
- Failure of the newborn to pass meconium
- Vomiting
- Abd distention
- Reluctance to feed
Hirschsprung disease barium enema findings
Narrow distal segment w/ sharp transition to the proximal dilated
Hirschsprung disease treatment
Surgical:
- Removal of aganglionic bowel-Temporary colostomy
- Surgical reconstruction
What is the MC long-term complication of Hirschsprung disease?
Fecal incontinence
What is the MC congenital anomaly of the GI tract
Meckel’s Diverticulum
Define Meckel’s Diverticulum
Outpouching or bulge lower part of the small intestine
What is the rule of two’s in Meckel’s Diverticulum?
- 2% of the population
- 2:1, M:F
- first 2 yrs of life=50% of complications occur then
- Within 2 feet from the ileocecal valve
- 2 inches in length
Meckel’s Diverticulum clinical presentation
- Asymptomatic-usually
- Painless lower GI bleeding
- Mimic appendicitis
Meckel’s Diverticulum diagnosis
- Arteriography or CT angiography
2. Meckel’s scan: radionuclide scan
Define Pilonidal Cyst
Infxn of skin or subQ tissue at/near upper part of natal cleft of the buttock
Pilonidal Cyst RF’s
overweight/obesity local trauma or irritation sedentary lifestyle or prolonged sitting deep natal cleft family hx
What are pinworms called?
enterobiasis
Pinworm si/sx
intense anal pruritus
Pinworm treatment
Pyrantel pamoate 11mg/kg (max 1g): Repeat after 2 weeks
*Tx everyone in the house
Define encopresis
Repeated passage of feces into inappropriate places:
- @ least 3 months
- @ least 4 years of age
encopresis treatment
Behavioral-educational tx
Biofeedback therapy
Pharmacotherapy treatment in encopresis
- Suppositories & enemas: Miralax (initially)
2. Laxatives: Milk of magnesia (maintenance)
Jaundice treatment
- Phototherapy: Unconjugated bilirubin absorbs light
3. Transfusion-if severe
Define Gilbert’s Syndrome
Familial hyperbilirubinemia: Autosommal dominant (common)
Who is Gilbert Syndrome MC in?
Males
What are the 4 primary organs that Cystic Fibrosis effects?
- Lung
- Pancreas
- Intestine
- Liver
Complications of the pancreas in CF?
- Fat soluble vitamin deficiency
- Steatorrhea
- Malnutrition
Complications of the intestine in CF?
CHO intolerance
Intussception
CF treatment
- Pancreatic enzyme supplementations
2. Ursodiol: cholestasis tx