GI Flashcards
Specialized columnar epithelium and goblet cells seen in a biopsy from distal esophagus?
Barrett’s esophagus
Biopsy of a pt with esophagitis reveals large pink intranuclear inclusions and host cell chromatin that is pushed to the edge of the nucleus
HSV-1 esophagitis
biopsy of mass in parotid gland reveals a double layer of columnar epithelial cells resting on a dense lymphoid stroma
Warthin’s tumor
small intestine biopsy reveals small lymphocytes with irregular nuclear contours and proliferation of these lymphocytes into mucos and epithelial glands
MALT lymphoma
Outpouching of all layers of the esophagus found just above the LES
Epiphrenic diverticulum
Basal cell hyperplasia, eosinophilia, elongation of lamina propria papillla seen in biopsy of esophagus
chronic reflux esophagitis
stomach biopsy reveals lymphoid aggregates in lamina propria, columnar absorptive cells, atrophy of glandular structures
chronic gastritis
protrusion of mucosa in the upper esophagus
Esophageal web - Plummer vinson syndrome
Biopsy of patient with esophagitis reveals enlarged cells, intranuclear and cytoplasmic inclusions and clear perinuclear halo
CMV esophagitis
Diffuse thickening of gastric folds, elevated serum gastrin levels, biopsy reveals glandular hyperplasia without foveolar hyperplasia
zollinger ellison syndrome
Biopsy of mass in parotid gland shows both epithelial and mesenchymal differentiation
pleomorphic adenoma
Biopsy of mass from parotid gland reveals a carcinoma composed of mostly mucus-secreting cells but also some squamous cells and intermediate hybrids of both
mucoepidermoid tumor
a PAS stain on a biopsy obtained from pt with esophagitis reveals hyphenated organisms
candida esophagitis
most common cause of duodenal ulcers
H. Pylori
esophageal pouch found in upper esophagus
Zenger Diverticulum
Most common cause of RLQ pain
Appendicitis
50 year old femail presents with pruritis w/out jaundice, lab reveals + AMA
primary biliary cirrhosis
most common cause of acute LLQ pain
Diverticulitis
Gluten sensitivity
Celiac disease (sprue)
A patient with GI bledding has buccal pigmentation
Peutz Jeiger
60 yr-old female with rheumatoid arthritis and no alcohol history presents with fatigue and right abdominal pain, lab studies reveal high levels of ANA and ASMA, elevated serum IgG levels and no viral serologic markers
Autoimmune hepatitis
colonoscopy reveals very friable mucosa extending from rectum to distal transverse colon
Ulcerative colitis
Small intestinal mucosa laden with distended macrophages in lamina propria (filled with PAS + granules and rod-shaped bacilli seen by electron microscopy)
Whipple’s Disease
Most common cause of RUQ pain
cholecystitis
liver biopsy on 23 yo female with elevated levels of LKM-1 Abs, no alcohol hx and no viral serological markers reveals infiltration of the portal and periportal area with lymphocytes
autoimmune hepatitis
diarrhea, fever, abdominal cramps following course of abx
pseudomembranous colitis
Fatal disease of unconjugated bilirubin resulting from complete lack of UDPGT activity
criggler Najar I
radiography reveals a “string-sign” in terminal ileum
Crohn’s disease
Total or subtotal atrophy of the small bowel villi, plasma cells and lymphocyte infiltration into the lamina propria and epithelium and hyperplasia/elongation of crypts
celiac sprue
nonfatal disease of unconjugated bilirubin resulting from low levels of UDPGT activity
CN II or Gilbert’s syndrome
Elevated levels of serum ferritin and increased transferrin saturation
Hemochromatosis
alpha-fetoprotein levels > 1000 pg/mL
Hepatocellular Ca
elevated serum copper, decreased serum ceruloplasmin, and elevated 24 hr urinary copper
Wilson’s disease
liver disease and lung emphysema
alpha-1 antitrypsin deficiency
ERCP reveals alternating strictures and dilation
Primary sclerosing cholangitis
