GI

Question 2

what group has vast endotoxin production including alpha hemolysis

Answer 2

E.coli

Question 3

what is the shiga like toxin

Answer 3

Found in both E.coli and shiggela, is a AB endotxin which is relased upon cell lysis.

Question 4

ETEC give the location, type of Diarrhea and some general epi. Toxins?

Answer 4

Active site is the small intestine and secretory diarrhea. Travellers diarrhea. heat Labile and heat stable enterotoxins

Question 5

EIEC give the location, type of Diarrhea and some general epi. Toxins?

Answer 5

active site is large intestine, Dysentrery, younger children in developing contrys, fever and cramps are associated due to the tissue invasion which is possible due to polymerization of cells which meidates movement cell to cell.

Question 6

EPEC give the location, type of Diarrhea and some general epi. Toxins?

Answer 6

small intestine, secretory diarrhea, charateristic of childhood diarrrhea, no toxins uses sectroy proteins to cause deformation of cytoskeleton which causes is secretory diarrhea.

Question 7

EHEC give the location, type of Diarrhea and some general epi. Toxins?

Answer 7

large intestine, diarrhea is caused by infamation rather then tissue invasion thus diarrhea is hemarogic coloitis. yes produces verodoxin which causes inflamation leading to adbominal pain. sources are either person to person but mostly transmitted through contaminated food.

Question 8

EAEC give the location, type of Diarrhea and some general epi. Toxins?

Answer 8

Site of infection is small intestine, bloody watery diarrhea which may or may not have puss. STX toxin production. very long incubation period.

Question 9

in which kind of infection would a relapse be expected or possible

Answer 9

Salmonella as it can enter a presiter state in the host macrophages

Question 10

what is the main mech of disease for salmonella

Answer 10

inflammatory repones

Question 11

which bacteria needs a larger enoculume to cause disease salmonella or shiggela

Answer 11

salmonella bc shigella needs as little at 100 organisms to cause disease

Question 12

what is the causative agent for the plague

Answer 12

Yersinia persistis

Question 13

what are the 2 forms of the pleague and what are there charateristics

Answer 13

bubonic- caused by a insect bite which infects lympatic system

Pnumonic- from human and infectes lungs through inhalation of air born infected droplets

Question 14

is the cycle seen with yersinia persitis

Answer 14

• sylavatic and urban cycle which sees animals and insects remaining as a massive resivoir for the pleague and cycle the infection within there population which then may come into conctact with humans which then sees a cycle of humans creating insect carrier which then begin the cylavaitic cycle over again this is why it is so challanging to rid the world of the pleague

Question 15

what is a key feature which allows necrosis in the pleague

Answer 15

yersinias ability to bind organic iron from heme in blood

Question 16

how does S.aureus cause Disease in GI

Answer 16

intoxication via enterotoxin commonly enterotxin A which causes intesnse vomiting along with secrtory diarrhea

Question 17

why is S.aureus so common in food related illness

Answer 17

BC high salt and sugar tolerance, also when heating kills bacteria but does not removed the heat stable enterotoxin

Question 18

what are the 2 forms of disease cauased by bacillus cereus

Answer 18

• heat stable toxin form which causes vomiting and is associated w rice
• Heat labile form which is the darrheal form which is associated w meat or veggies

Question 19

what is unquie about campylobacter

Answer 19

Microaerophilic conditions

• this bacteria causes frequent bloody stools which can last more then a week

epi- comes from farm related animals and infections in humans is from injestion of infected diseases

Question 20

what is super unique about helipbacter

Answer 20

has a distinct helical shape

Question 21

what is very charaterictic of Vibrio cholerare

Answer 21

Vibrio chloerare is know widly for 2 things first of which being its ability to produce the cholera toxin which is secreted in huge quanities which in turn causes disease. The disease it self is also known for causeing huge secrtory diarrhea. (active site is small intestine)

Question 22

how does helopbacter avoid stomach acids

Answer 22

• production of urase which increase local pH