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Patho 3 > GI 1 > Flashcards

GI 1 Flashcards

1
Q

1 cause of esophagitis

A

GERD

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2
Q

Barretts esophagus

A

metaplasia of lower esophagus (strat squamous change to columnar w/goblet cells), typically adenocarcinoma from GERD

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3
Q

MC GI cancer

A

adenocarcinoma

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4
Q

Mallory-Weiss Syndrome

A

longitudinal tears at gastric junction, presents w/hematemesis

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5
Q

How are esophageal varices developed?

A

portal HTN, asymptomatic till rupture where 40% die, tx w/propranolol

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6
Q

benign tumor of esophagus

A

leiomyoma

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7
Q

esophageal squamous cell carcinoma

A

5 year survival rate, 70% within one year

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8
Q

parietal cells

A

secrete HCl and intrinsic factor (help absorb B12)

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9
Q

chief cells

A

secrete pepsin

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10
Q

G cells

A

secrete gastrin, which stimulates secretino of gastric acid by parietal cells

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11
Q

hematemesis vs

melena

A

vomiting of blood, commonly from PUD

dark, digested blood

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12
Q

MCC of upper esophageal disease

A

peptic ulcer disease

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13
Q

gastric ulcer vs

duodenal ulcer

A

pain with food

pain goes away after eating bc of bicarb

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14
Q

how can NSAIDS cause PUD

A

block prostaglandins

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15
Q

benign gastric tumors

A

polyps

leiomyomas

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16
Q

Hirschsprung disease

A

aka toxic megacolon

17
Q

transmural ischemic bowel disease complaints

A
  • sudden pain out of proportion to physical signs
  • bloody diarrhea
  • abdominal pain after eating
18
Q

true vs false diverticula

A

true contain all 3 layers of bowel

false only contains serosa and mucosal layer

19
Q

MCC of SBO

LBO

A

adhesions from prior sx

mass

20
Q

Celiac disease

A

genetic susceptibility HLA-DQ2

21
Q

MC inflammatory bowel disease

A

-ulcerative colitis
large intestine, continuous ulcers
blood mucoid diarrhea
primary sclerosing cholangitis

22
Q

Chrohns disease

A

transmural, affects entire GI tract
can get granulomas
skip/cobblestone appearance
macrocytic anemia (B12)

Patho 3 (4 decks)

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