Ghost in your genes video questions

Question 1

Did the children of women pregnant during 9/11 show abnormal stress markers?

Answer 1

Yes, they showed abnormal stress markers and increased vulnerability to PTSD.

Question 2

During which period of pregnancy were fetuses most vulnerable to stress effects from 9/11?

Answer 2

The third trimester.

Question 3

What developmental period is critical for transgenerational effects observed in the Swedish village study?

Answer 3

The pre-puberty stage of the paternal grandfather.

Question 4

What is the genetic basis for the phenotypic divergence between Angelman and Prader-Willi syndromes?

Answer 4

Angelman syndrome is caused by loss of maternal UBE3A gene function; Prader-Willi syndrome is caused by loss of paternal gene function on chromosome 15q11-q13, due to deletions, uniparental disomy, or imprinting defects.

Question 5

What are the genetic and epigenetic causes of Beckwith-Wiedemann syndrome?

Answer 5

Genetic: Mutations in CDKN1C, copy number variations. Epigenetic: Abnormal DNA methylation at imprinting control regions, loss of imprinting, or gain of methylation.