GH adenoma Flashcards
1
Q
fancy name?
A
somatotrophs
2
Q
presentation in pre-pubertal/post?
A
pre = gigantism post = acromegally
3
Q
features of acromegally?
A
large hands and feet coarse face, large tongue and uvula -> sleep apnea arthropathies LVH -> arrhythmias DM
4
Q
mass effects
A
hydrocephalus
opthalmophegia
5
Q
diagnosis
A
increased levels of IGF-1
6
Q
treatment
A
surgery plusminus octreotide
7
Q
genetic factors
A
MEN-1 and Carney’s complex
8
Q
describe high density mono-hormonal cells
A
cuboid epi, monomorphic, R/O nuclei
9
Q
describe low density mono-hormonal cells
A
pleomorphic and fibrous bodies that produce keratin
10
Q
describe multi-hormonal cells, individual type
A
mammosomatotrophs, densely granulated
11
Q
describe multi-hormonal cells, multiple type
A
mixed tumor
