ACTH tumor Flashcards
1
Q
production of?
A
proopiomelanocortin (POMC)
2
Q
epidemiology?
A
M:F 1:8, ~30-40 years old
3
Q
clinical features?
A
fat @ neck, abdomen, supraclavicullar, DM immunocomp neuropysch purple stria
4
Q
diagnosis
A
measure urine cortisol @ 24 hrs
demonstrate loss of circadian cortisol
plasma ACTH levels
5
Q
gross and histo
A
soft/red
monomorphic, R/O, lots of cytoplasm
6
Q
describe silent tumors
A
do not produce hypercortisolism symptoms but are more clinically aggressive
