gfr Flashcards

1
Q

kidney filters plasma how many times a day

A

about 60 times

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

filtrate =

A

plasma – proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

glomerular capillaries are drained by

A

arterioles not venules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

GFR formula

A

GFR: kf ((HPGC - HPT) - (OPGC - OPT))

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

hydrostatic pressure of glomerular capillaries (HPGC)

A

45-60 mmHg (higher than hydrostatic pressure of systemic capillaries which is about 15-35 mmHg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

oncotic pressure of glomerular capillaries (OPGC)

A

20 - 25 mmHg at afferent arteriolar end this increases to 35 mmHg at efferent arteriolar end (because proteins become highly concentrated after filtration of about one fifth of the plasma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

hydrostatic pressure of bowman’s space (HPT)

A

against filtration = 18 mmHg (increased in urinary tract obstruction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

oncotic pressure of bowman’s space (OPT)

A

zero (because proteins are not filtered to the Bowman’s space)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

surface area of the membrane (SA)

A

0.8 m2 (for both kidneys)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

surface area of the membrane increases or decreases by

A

contraction or relaxation of mesangial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

decrease mechanism of mesangial cells is through

A

angiotensin 2 endothelia ADH, histamine leukotrienes and catecholamine decreases the SA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

increase mechanism of mesangial cells is through

A

relaxation by ANP cAMP and dopamine increases the SA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

substance used to measure gfr

A

inulin and creatine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

fructose polymer administered by intravenous (I.V.) infusion

A

inulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

produced from creatine kinase (phosphocreatine) in muscles

A

creatine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly