gestational diabetes Flashcards
what are the hormones responsible for normal GDM
human placental lactogen, glucocorticoids, progesterone, TNF-alpha and FFA
definition of GDM
glucose intolerance diagnosed during pregnancy
maternal complications of GDM
preecalmpsia, polyhydramnios, asymptomatic bacteria and UTI
fetal complications of GDM
stillbirth, macrosomia, hypoglycemia, jaundice, hypocalcemia, tetralogy, truncus arteriosus
screening protocol for GDM
at 24 and 48 weeks a 50g glucose challege, measured at 1 hour, then a 100g at 3 hour if necessary
treatment for GDM
metformin and glyburide
risk of progression to Type2DM is correlated with
severity of impairment of insulin secretion
increased risk of progression to T2DM postpartum correlated with what test?
failure of oral glucose challenge 6-12 weeks postpartum