Geriatrics Flashcards

1
Q

What is geriatric medicine?

A

Branch of general medicine concerned with older people
Older people are main users of both health and social services
Challenges of frailty, complex co-morbidities, different patterns of disease presentation, slower response to treatment and requirements for social support call for special medical skill

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2
Q

What is frailty?

A

State of increased vulnerability resulting from ageing associated decline in reverse and function across multiple physiologic systems such that the ability to cope with everyday or acute stressors is compromised

  • Not inevitable
  • Not simply due to multiple long term conditions
  • Not irreversible
  • Poor functional reserve
  • Vulnerable to decompensation when faced with illness, drug S/E, metabolic disturbance
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3
Q

How do complex co-morbidities relate to geriatrics?

A

Often people who are older have more diagnoses than those who are younger
Can be linked
Can be unlinked
Acute presentations on top of this
People with frailty and co-morbidities often have prolonged death and their decline often more unpredictable
How important is it to start treatments that take months to work?

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4
Q

What conditions may present differently in older people?

A
Falls
Confusion
Off legs - generally unwell
Incontinence
Chest pain, SOB, urinary symptoms
Social admission
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5
Q

What are the 5M’s of geriatric giants?

A
Mind
Mobility
Medications
Multi-complexity
Matters most
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6
Q

What does mind mean?

A

Dementia
Delirium
Depression

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7
Q

What does mobility mean?

A

Impaired gait and balance

Falls

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8
Q

What do medications mean?

A

Polypharmacy
Deprescribing/optimal prescribing
Adverse effects
Medication burden

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9
Q

What does multi-complexity mean?

A

Multi-morbidity

Bio-psych-social situations

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10
Q

What does matters most mean?

A

Individual meaningful health outcomes and preferences

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11
Q

What is a social admission?

A

Non-specific presentations are tricky
Medical slang
Used to describe patients unable to cope with ADLs
No acute medical problem, inappropriate admission
Negative
Often have serious underlying pathology that will be missed if you don’t search

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12
Q

What is the treatment like in geriatric medicine?

A
Essentially the same
Much more prone to S/E and interactions
Reduced organ function
Lack of evidence for treatment in older patients
Often multiple patholgies to balance
How relevant is secondary prevention when you're old
Polypharmacy
Slower response to treatment
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13
Q

What is deconditioning?

A

Bedbound for days/weeks
Confused
Poor nutritional state even prior to admission, made worse by acute illness
Can’t walk, falls, can’t look after themselves
Need more than just medicines
Comprehensive geriatric assessments
- Tailor social and environmental assessment to patient
- Require MDT

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14
Q

What do you need to take into account in rehabilitation?

A

Process of restoring patient to max function (need to know pre-morbid function)
Can happen in variety of settings, in and out of hospital
Involves MDT, including doctors
Leads to process of discharge planning

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15
Q

What are the legal and ethical issues?

A

Care at end of life (fluids, feeding, antibiotics)
Discharge destination
Dementia/delirium
MCA

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16
Q

What is important to take into account with vulnerable patients?

A

Safeguarding
Abuse
Physical - neglect, psychological, financial, discriminatory, institutional, sexual

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17
Q

What is important to take into account with death and dying?

A
Lots of patients die
Inevitable consequence of illness
Important we recognise dying and act appropriately
One chance to get it right
May be difficult or upsetting
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18
Q

What is the NEWS score?

A

Score that determines illness of a patient and how quickly we need to act

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19
Q

What assessments should you do during ABCDE?

A

NEWS
GCS
AMI

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20
Q

What investigations should you do for pneumonia?

A

Disability - GCS, AMT, blood glucose
Bloods + culture, ABG
Raised neutrophils - bacterial infections
CXR - to see R lower lobe do lateral film
ECG
Sputum culture
Urine for pneumococcal antigen and legionella in moderate and severe CAP
CURB65

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21
Q

What are the scores in CURB65?

A
Confusion AMT = / 7
Urea > 7
RR > 30
BP S < 90 D = / < 60
Age > 65
Score
- 0-1 < 3% mortality
- 2 9% mortality
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22
Q

How do you manage pneumonia?

A

High flow O2
Antibiotics - clarithromycin + co-amox IV
Paracetamol if pyrexic
Fluids if AKI

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23
Q

What are the features of consolidation?

A

Dull to percussion
Crepitations
Bronchial breathing
Describe limitations of consolidation

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24
Q

What is HAP?

A

More than 48 hours after admission
Different antibiotic approach - broad spectrum
G -ve MRSA
AB policy will tell you what to prescribe depending on C/HAP and CURB65

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25
What should you think of in a patient with pneumonia and a stroke?
Aspiration pneumonia
26
What are the symptoms of aspiration pneumonia?
``` Chest pain Coughing Fatigue Fever SOB Wheezing Breath odor Excessive sweating Problems swallowing Confusion Blue discolouration of skin ```
27
What does COVID pneumonia look like?
Affects edge of chest and lower lobes most Ground glass appearance ARDS - completely opaque chest
28
How do you manage COVID pneumonia?
``` Isolate NO ABX O2 Supportive care - rest, VTE prophylaxis, management of co-morbidities, fluids, immunosuppressant alteration Early ID of illness monitoring ```
29
What are the complications of pneumonia?
Post-pneumonia pleural effusion Lung abscess after pneumonia - consolidation can become neurotic has fluid level on MRI Pus in pleural sac - empyema
30
What should you look out for in a geriatric with infection?
Sepsis
31
What could LIF pain with pyrexia suggest?
Diverticulitis +/- abscess | Peritonitis
32
What is vesicular breathing?
Normal
33
What is bronchial breathing?
Longer expiration
34
What is air under the R diaphragm called?
Pneumoperitoneum
35
What is erysepilas?
Red skin caused by strep penicillin Tx
36
When should you give fluids in sepsis? And what would you prescribe?
If systemic symptoms like sinus tachycardia, CPT, BP Fluid resuscitation (bolus saline 500mls over 15 mins) Reassess and repeat if required
37
What antibiotic should you give for intra-abdominal sepsis?
Tazacin
38
What investigations should you do for someone with sepsis?
``` FBC, CRP Blood cultures U&E, LFTs Lactate, blood glucose Lactate - raised if tissue damage CT abdo pelvis if abdo symptoms ```
39
What is sepsis?
Systemic inflammatory response to infection
40
What is the sepsis 6?
``` Fluids - fluid balance chart, fluid resus Blood cultures Abx - IV Urine output Lactate O2 - 24% O2 PO2 > 94% ```
41
How else should you treat sepsis?
``` NBM Analgesia IV Anti-emetics if morphine Fluid balance - maintenance 30ml/kg/day KCl 1mmol/kg ```
42
Why is potassium needed in the body?
Vital for regulating normal electrical activity of the heart
43
What happens when K+ increases in the body?
Reduced myocardial excitability, with depression of both pacemaking and conducting tissues
44
What happens with progressively worsening hyperkalaemia?
Suppression of impulse generation by SAN and reduced conduction by AVN and his-purkinje system leading to bradycardia and conduction blocks
45
What is the definition of hyperkalaemia?
K+ > 5.5 Moderate > 6.0 Severe > 7.0
46
What does an ECG of hyperkalaemia look like?
``` Tall tented T waves (repolarisation abnormalities) > 5.5 Absent P waves (progressive paralysis of atria) > 6.5 Prolonged QRS and bradycardia > 7 Cardiac arrest > 9 Tall tented T waves Prolonged PR segment Loss of P waves Bizarre QRS Sine wave (pre-cardiac arrest) ```
47
What are the causes of hyperkalaemia?
``` MACHINE Medications Acidosis - metabolic/respiratory Cellular destruction Hypoaldosteronism (Addison's) or haemolysis Intake - excess Nephrons/renal failure Excretion impaired ```
48
What medications can cause hyperkalaemia?
ACEi NSAIDs Potassium sparing diuretics - spironolactone Trimethoprim
49
What are the signs and symptoms of hyperkalaemia?
``` MURDER Muscle weakness Urine - oliguria, urea Respiratory distress Decreased cardiac contractility ECG changes Reflexes - hyper/areflexia ```
50
What is the management of hyperkalaemia?
AIRED Administer IV calcium gluconate 10ml IV slowly with ECG monitoring/repetition Increased excretion - calcium resonium 15g 8hr intervals to help excrete through gut Remove sources of potassium - IV/oral Enhance potassium uptake into cells - insulin 10 units in 50ml 50% dextrose over 15 mins in large vein OR 10/20% dextrose in 250ml over 60 mins Dialysis if severe Also add salbutamol 10mg nebuliser
51
What is the definition of hypokalaemia?
K+ < 3.5 Moderate < 3 Severe < 2.5
52
What are the ECG changes in hypokalaemia?
``` Increased amplitude and width of P wave Prolongation of PR interval T wave flattening and inversion ST depression Prominent U waves Apparent long QT interval due to fusion of T and U waves Ectopics Supraventricular tachyarrhythmias ```
53
What are the causes of hypokalaemia?
Body trying to DITCH K+ - Drugs - loop diuretics - Inadequate consumption - Too much water - Cushing's - Heavy fluid loss
54
What are the signs and symptoms of hypokalaemia?
7Ls (low) - Lethargic - Low, shallow respirations... failure - Lethal cardiac disrhythmias - Lots of urine (frequency and large volume) - Leg cramps - Limp muscles - Low BP (severe)
55
What is the management of hypokalaemia?
Oral or IV K+
56
What is diabetes?
Chronic health condition where blood glucose level is too high Happens when the body doesn't produce enough insulin or when you can't produce any at all In older adults most likely to be T2
57
How common is diabetes?
1 in 15 people have diabetes - including 1 million people who have T2 but haven't been diagnosed
58
How do older adults differ in diabetes?
``` Clinical presentation Psychosocial environment Resource availability Living situation Degree of available social support ```
59
What are the signs and symptoms of T2DM?
``` Polyuria and polydipsia Increased hunger Unintended weight loss Fatigue Blurred vision Slow healing sores Frequent infections Numbness or tingling in hands or feet Areas of darkened skin - usually in armpits and neck Repeatedly getting thrush ```
60
How is diabetes management in the elderly different?
Individualised care plan - take into account age, preferences, co-morbidities, and risk of adverse effects from medications Lifestyle modification but not restrictive diets Medication - consider drug interactions and risk of hypoglycaemia Exercise - consider physical abilities HbA1c goal equivalent to co-morbidities/end of life
61
What special considerations should you make for elderly with diabetes?
Presence of age-related conditions and interference with ability to perform diabetes self care Polypharmacy - increased risk of drug interactions Visual impairments - social isolation, errors in treatment, traumatic falls, disability Risk of hypoglycaemia and risk of triggering CVS events and increased falls and fracture risk
62
What investigation should you do for diabetes?
Urine dip | HbA1c, fasting glucose, random plasma glucose
63
How is diabetes diagnosed?
If symptomatic - single abnormal HbA1c or fasting glucose If asymptomatic - repeat testing HbA1c > 48 Fasting > 7 Random > 11.1 in presence of S&S of diabetes
64
What is the cause of diabetes?
Cells in muscle, fat and liver become insulin resistant Cells don't make enough sugar as don't respond to insulin Pancreas can't make enough insulin due to fatty deposits in beta-cells and cells become impaired
65
How can you prevent diabetes?
``` Healthy lifestyle Eating healthy foods Active Weight loss Avoiding inactivity for long periods Medication to prevent progression from prediabetes ```
66
What are the risk factors for diabetes?
``` Overweight Fat distribution Inactivity Family history Black, hispanic, native american, asian, and pacific islander ethnicities High levels of trigylcerides Increasing age Prediabetes Pregnancy-related risks POCS ```
67
What are the complications of diabetes?
``` Skin conditions Slow healing Hearing impairment Sleep apnoea Dementia Macrovascular - IHD - PVD - Cerebrovascular disease Microvascular - Retinopathy - Nephropathy - Neuropathy ```
68
What are the complications of diabetes in older adults?
More at risk for acute and chronic vascular complications Major lower extremity amputations, MI, visual impairments, ESRD Over 75 more likely to develop complications, higher rates of death from hyperglycaemic crises, and increased rate of ED visits Higher risk of geriatric syndromes
69
Name 4 examples of geriatric syndromes
``` Cognitive dysfunction Depression Physical disability Pain Polypharmacy Urinary incontinence ```
70
What is osteoporosis?
Progressive loss of bone mass associated with change in bone micro-architecture Associated with reduced cross linking within trabecular bone resulting in cortical thinning
71
How does remodelling work?
Osteoblasts - make bone Osteoclasts - destroy bone Balance between the two Allows bone to adapt to stressors and repair microdamage
72
What happens in osteoporosis?
Shift towards bone resorption leading to net bone loss Osteoclasts function in less regulated manner perforating through trabecular plate No framework for osteoblast activity and structural integrity lost Loss of connectivity between trabecular plates typical of microstructural changes associated with osteoporosis
73
What are the risk factors for osteoporosis?
SHATTERED Steroid use of > 5mg for > 3 months Hyperthyroidism, hyperparathyroidism, hypercalciuria Alcohol and tobacco use Thin BMI < 18.5 Testosterone decreased eg in prostate cancer treatment Early menopause Renal or liver failure Erosive/inflammatory bone disease eg myeloma or rheumatoid arthritis Dietary calcium decreased/malabsorption, diabetes mellitus type 1
74
What investigations should you do in osteoporosis?
Bloods - FBC, U&E, LFT, TFT, calcium, phosphate, vit D, PTH, coeliac serology, myeloma screen DEXA Spinal x-ray Bone turnover markers
75
What is the management of osteoporosis?
``` Lifestyle changes Vitamin D and calcium Bisphosphonates Denosumab - monoclonal antibody Raloxifene - selective oestrogen receptor modulator Teriparatide - anabolic ```
76
What are the complications of osteoporosis?
Bone fractures | Hip fractures - disability, increased risk of death especially in elderly
77
How does skin protect against pressure damage?
Pacinian corpuscles - receptors that detect pressure changes/vibration on skin pH mantle between 4-6 maintaining normal flora Sebum production - antimicrobial and sealant properties Langerhans cells providing tissue immunity Effective perfusion to skin
78
What is a pressure ulcer?
Injury to skin and underlying tissue that predisposes patient to infection - life threatening
79
How do pressure ulcers form?
Localised external pressure on skin - occlusion of capillaries and tissue compression - Insufficient O2 and nutrients reaching tissues - Altered soft tissue hydration - fluid pushed away from viable cells Can affect any area of the body put under pressure - most common on bony areas of body
80
What are the risk factors for pressure ulcers?
``` Limited mobility Sensory impairment Malnutrition Dehydration Obesity Cognitive impairment Urinary and faecal incontinence Reduced tissue perfusion ```
81
What is slough?
Yellow-green layer with pale pink base - mixture of fibrin, cell breakdown products, serous exudate, leukocytes and bacteria, doesn't necessarily imply infection and can be part of normal healing process
82
What is eschar?
Tan/brown/black dead skin that sheds and falls of skin
83
What are stage 1 ulcers like?
``` Non-blanching erythema - Skin intact - Non-blanching redness - Localised - Painful - Bluish tinge - Warm May be difficult to detect in patients with deeper skin tones ```
84
What are stage 2 ulcers like?
``` Partial thickness tissue loss Loss of dermis - shallow open ulcer Red/pink wound bed - no slough May also present as blisters - open/ruptured, serum fulled Not to be confused with moisture lesions ```
85
What are stage 3 ulcers like?
Full thickness tissue loss Subcutaneous fat may be visible Bone, tendon, or muscle NOT visible or directly palpable Slough or eschar may be present Wounds with 100% eschar or slough at least stage 3
86
What is a moisture lesion?
``` Redness or partial thickness skin loss of epidermis, dermis or both Caused by excessive moisture - Urine - Faeces - Sweat Not to be confused with pressure ulcers ```
87
What is a stage 4 pressure ulcer?
Full thickness tissue loss Exposed bone, tendon or muscle - visible or directly palpable Depth of stage 3 and 4 can depend of anatomical structure High risk for osteomyelitis
88
What is an unstageable pressure ulcer?
Base of ulcers need to be visible in order to stage Some can be completely covered by slough or eschar Cannot be stage but must be 3 or 4
89
What does a deep tissue injury look like?
Damage of underlying soft tissue Purple localised area of discoloured intact skin Blood-filled blister May be painful or warm May expose additional layers of tissue despite optional treament
90
What is an acquired pressure ulcer?
Occur within care facility
91
What is an inherited pressure ulcer?
Patient moves into facility with ulcer
92
What can pressure ulcers to classified as?
Acquired/inherited Avoidable/unavoidable 95% unavoidable
93
When are pressure ulcers reported as clinical incidents?
Stages 2, 3, 4 | 3 and 4 serious
94
How are pressure ulcers treated?
``` Changing positions to relieve pressure on already developed ulcers and prevent more Mattress and cushions Dressings Barrier creams Antibiotics if required Diet and nutrition Hydration Debridement - surgical or maggots Surgery ```
95
How do you prevent pressure ulcers?
``` SSKIN Support surface Skin assessment Keep moving Incontinence and moisture Nutrition and hydration ```
96
What are the causes of iron deficiency anaemia?
Decreased iron intake Increased iron loss Increase iron requirements - not common in the elderly
97
What are the signs and symptoms of iron deficiency anaemia?
``` Often asymptomatic and only causes mild symptoms Fatigue Dyspnoea Headache Palpitations Pale skin or conjunctiva ```
98
What are the symptoms of underlying conditions that could be associated with iron deficiency anaemia?
Dysphagia - oesophageal malignancy Dyspepsia - gastric cancer, PUD Abdominal pain - coeliac disease, intrabdominal malignancy, IBD Change in bowel habit - bowel cancer, coeliac disease, IBD Rectal bleeding - anal fissure, rectal cancer, haemorrhoids, IBD Weight loss - IBD, bowel cancer
99
What is the clinical presentation of iron deficiency anaemia?
``` Conjunctival pallor Angular chellitis Atrophic glossitis Koilonychia Dry skin and hair ```
100
What is the criteria for iron deficiency?
Hb < 130 in men | Hb < 120 in women
101
What are the investigations for iron deficiency?
``` FBC - Hb and haematrocrit - MCV - MCH - RDW Ferritin Transferring saturation and total iron-binding capacity Blood film Urinalysis ```
102
What is the treatment for iron deficiency anaemia?
Eat more iron-rich foods eg dark-green leafy vegetables Oral iron binding replacement therapy S/E - nausea, GI irritation, constipation or diarrhoea Ascorbic acid supplementation IV iron replacement Red cell transfusion
103
What are the complications of iron deficiency anaemia?
More at risk of illness and infection | Higher risk of heart failure with severe anaemia
104
What are the common neural causes of syncope?
Vasovagal syncope Carotid sinus hypersensitivity Situational eg micturition
105
What are the common cardiac causes of syncope?
Postural hypotension | Arrhythmias eg bradycardia, tachycardia, hypotension, long QT
106
What types of bradycardias can cause syncope?
Heart block/sick sinus syndrome
107
What types of tachycardia can cause syncope?
VT/SVT
108
What are the common non-cardiogenic causes of syncope?
Psychogenic Metabolic Medications
109
What are the clinical features suggesting cardiac causes of syncope?
``` SOB Reduced exercise tolerance or happened during exercise Chest pain or palpitations Oedema Heart murmurs No prodrome Symptoms occur when sitting and lying down FHx of sudden cardiac death ```
110
What is postural hypotension?
Persons blood pressure drops abnormally when they stand up after sitting or lying
111
How do you test postural hypotension?
Symptomatic gives diagnosis Standing for more than 3 minutes - check multiple times over these minutes First thing in the morning and check a few times throughout the day as they can be situational
112
What is the rate of drop to diagnose postural hypotension?
Drop by S > 30, or D > 20 | S < 90
113
What are the causes of falls in older people?
``` Cardiac causes Neural causes Metabolic causes Balance problems Muscle weakness Poor vision Heart disease Syncope Dementia Hypotension ```
114
What are the complications of falls?
``` Fractures Head injuries Pressure sores Becoming less active and therefore weaker and increased chance of falling - post fall syndrome Carpet burns ```
115
What are the complications of long stays on the floor following falls?
``` Dehydration Hypothermia Pneumonia - related to hypothermia AKI - from dehydration and rhabdomyolysis Rhabdomyolysis Death Distress ```
116
What is vasovagal syncope?
Syncope due to stress
117
What stressors can cause vasovagal syncope?
Pain/heat Sight of blood Prolonged standing Mental stress
118
What is carotid sinus hypersensitivity?
When external pressure is placed on the carotid sinus automatically reduced HR - normal In hypersensitivity - overreacts to pressure causing HR to slow down or BP to drop significantly Can be by wearing tight clothing around neck or turning head
119
What is sick sinus syndrome?
SAN cannot create a HR that is appropriate for body's needs Causes irregular heart rhythms Previous MI
120
Name 2 intrinsic risk factors for falls
Female Cognitive decline Visual problems Muscle weakness
121
Name 2 extrinsic risk factors for falls
Polypharmacy | Lots of hazards around home
122
What are the causes of postural hypotension?
Age related impairment of baroreflex mediated vasoconstriction and chronotropic responses of heart Deterioration of diastolic filling of heart Dehydration Hypoglycaemia - secondary Adrenal disease - secondary Eating meals - postprandial hypotension Medications - recent changes?
123
How does COVID present?
``` Asymptomatic Mild viral illness Pneumonia Anosmia Loss of taste Thrombotic effects Renal failure Skin manifestations Respiratory failure Mortality ```
124
What are the risk factors for a more severe covid?
``` Ethnicity BMI Co-morbidities - diabetes, CVS Immunosuppressed Age ```
125
What investigations do you do in a suspected covid case?
Swab Bloods - FBC, U&E, CRP, LFT, PCT, ferritin, D dimer CXR - NAD, classic COVID change
126
What should you note about a covid patient?
Clinical frailty score Date of onset of symptoms Date of positive swab
127
What management should you put in place for covid patients?
``` Escalation plan DNAR Antibiotics Fluids Trail participant Phone family O2 Good nursing care Physio ```
128
What should you monitor in covid patients?
Sats | RR
129
What should you discuss with family?
``` General covid discussion Potential to suddenly deteriorate DNAR Escalation Regular follow-ups ```
130
What are the s/e of covid?
``` Delirium General decline and rapidly increased frailty Poor oral intake Unpredictable deterioration - Sudden increase in RR and drop in sats - Florid new changes on CXR - Check PCT again, give antibiotics if any indication - Increase O2 as needed - Most died, often very rapidly ```
131
What do you put in place for palliation?
``` O2 Rationalise medications Pre-emptive prescribing of drugs for symptoms control +/- syringe driver Update family ?visiting Support from whole MDT ```
132
What pre-emptive medications should you give someone who is dying?
Morphine Midazolam Hyoscine Haloperidol
133
What is the background of major trauma in the elderly?
Don't always present typically - often different mechanisms of injury Older patients have less senior reviews Most common cause of major trauma is small falls in elderly Frail patients with severe injuries are at risk of under-triage, delayed diagnosis, and sub-optimal care Osteoporosis under-diagnosed and under treated
134
How common are hip fractures?
66,500 hip fractures per year
135
What is the 30 day mortality for hip fractures?
7%
136
What is the year mortality for hip fractures?
30%
137
What are the NICE guidelines for hip fractures?
``` Orthogeriatric assessment within 72 hours Surgery within 36 hours Rehabilitation to as best function as possible Prompt mobilisation after surgery Pre-operative cognitive testing Delirium assessment post-operatively Return to original residence by 120 days Fracture prevention assessments Nutritional assessment ```
138
What are the two types of orthogeriatric care?
Fracture liaison services - Admitted under ortho - Provides input within 72 hours Dedicated orthogeriatric ward - Admitted directly to dedicated hip fracture ward - Usually admitted under ortho but transferred post-op - Both specialities provide input during admission
139
How can frailty be prevented?
Good nutrition Physical activity Avoid social isolation Not too much alcohol
140
What is the role of an orthogeriatrician?
``` Comprehensive geriatric assessment Pre-operative assessment Post-operative care Facilitate early rehabilitation Facilitate early supported discharge Communication - with patient, relative, friends, and carers ```
141
What happens in a geriatric assessment?
``` Functional status Cognitive status Medical problems/co-morbidities Geriatric syndromes Medications Nutritional status Social issues eg social support, finances, accomodation ```
142
What happens in a pre-operative assessment?
Assess severity of co-morbidities Medications review and analgesia Optimise to prevent delay to theatre Escalation and resuscitation decisions
143
What is the delirium assessment called and what does it assess for?
4AT Alertness AMT4 - ask the following - age, DOB, name of hospital, current year Attention - list months of year backwards Acute change or fluctuating course
144
How can you prevent delirium?
Ensure adequate CNS O2 delivery Correct any hypoperfusion, hypoxaemia, anaemia Maintain normal fluid and electrolyte balance Treat any fluid overload or dehydration Treat with analgesia appropriately through appropriate route Deprescribe any unnecessary or harmful medications Ensure bladder and bowel function Adequate nutritional intake Proper position for meals Nutritional supplements Detect and treat and major complications Ensure appropriate environmental stimuli Reassurance Early rehab and mobilisation
145
When should you administer analgesia in a hip fracture?
Immediately Assess within 30 mins of initial analgesia Hourly on ward Assess pain regularly to allow for movement, nursing care, and rehab At times of routine nursing obs
146
What analgesia should you give for a hip fracture?
``` Fascia iliaca nerve block Paracetamol Opioids (+laxative) at lowest effective dose - Buprenorphine patch - Dihydrocodeine or oxycodone Avoid NSAIDs/nefopam ```
147
What is the primary prevention of osteoporosis?
FRAX | If < 70 request DEXA
148
What is the secondary prevention of osteoporosis?
``` Non-pharmacological - Weight bearing exercises and muscle strengthening - Falls prevention - Smoking cessation and avoid alcohol Pharmacological - Calcium and vit D replacement - Bisphosphonates ```
149
What is important to remember when prescribing bisphosphonates?
Ensure no serious dental issues (risk of osteonecrosis of jaw) CI if CrCl < 30ml/min PO if probability > 1% unless GORD/PUD IV if probability > 10%
150
What is delirium?
Acute confusional state that fluctuates in severity and usually reversible, usually result of other organic process 1/3 will resolve quickly 1/3 will recover but much more slowly 1/3 will not recover to baseline
151
What is dementia?
Syndrome of acquired. chronic, global impairment of higher brain function, is an alert patient, which interferes with ability to cope with daily living Decline in memory with impairment of at least one other cognitive function such as skilled movements, language or executive function
152
What is BPSD?
Behavioural and psychological symptoms of dementia - heterogenous group of non-cognitive symptoms and behaviours eg agitation, irritability, depression, disinhibition, hallucinations
153
What are the symptoms of hyperactive delirium?
``` Agitation Delusions Hallucinations Wandering Aggression ```
154
What are the risk factors for delirium?
``` Old age Dementia Past H/0 delirium Significant co-morbidities Sensory impairment Change of environment ```
155
What are the causes of delirium?
PINCH ME - Pain - Infection - Nutrition - Constipation - Hydration - Medication - Environment DELIRIUM - Drug - introduction or adjustments - Electrolyte and physiological imbalances - Infection - Reduced sensory input - Intracranial problems - Urinary retention and constipation - Myocardial problems
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How do you manage hyperactive delirium?
``` Non-pharmacological first line - Orientation, reassurance - Continuity of care - staff/environment Sedation may be required if at risk to themselves or others Use lowest possible dose Usually quite reversible ```
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What are causes of a reversible dementia?
``` Depression B12/folate Hypothyroid NPH Substance misuse SLO Syphillis ```
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What are the symptoms of hypoactive delirium?
``` Lethargy Slowness with everyday tasks Excessive sleeping Inattention Can be confused with depression ```
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What are the complications of delirium?
High risk of death if untreated | Hypoactive has higher risk
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What is a TIA?
Neurological dysfunction caused by focal brain, spinal cord, or retinal ischaemia without evidence of acute infarction with symptoms lasting less than 24 hours
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What is the risk of stroke following a TIA?
At 2 days - 2-4.1% At 7 days 3.9-6.5%
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What treatment should you start with TIA immediately?
Aspirin and refer to TIA clinic
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What should influence the speed of your referral to TIA clinic?
ABCD2 score
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What investigations should you do following a TIA?
``` Bloods - FBC, WCC, U&E, CRP/ESR, LFTs, TFTs, haematinics ECG USS carotid Brain imaging Consider ECHO Consider 24 hr vs 72 hours tape ```
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What is a stroke?
Clinical syndrome characterised by sudden onset of rapidly developing or focal or global neurological disturbance which lasts more than 24 hours or leads to death, with no apparent cause other than that of vascular origin
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What are the 2 types of stroke and how common are they?
Ischaemic - 85% Haemorrhagic - Primary 10% - SAH 5%
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What are the differentials of stroke?
``` Migraine SDH Cancer Infection Hypoglycaemia Seizure PRES Functional ```
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What are the causes of an ischaemic stroke?
Atherosclerosis Cardio-embolism Dissection
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What imaging should you do for a stroke?
Within 1 hour CT head MRI
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What is the management of an ischaemic stroke?
``` Short term - Anti-platelets - Manage BP + acute management keep BP < 220/110 unless end organ damage - Thrombolysis - Thrombectomy - Endartectomy Long term - Lifestyle - salt, exercise, smoking, alcohol - Lipids aim to reduce by 40% - BP long term 130/80 Driving none for 1 month ```
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What is carotid endarterectomy?
Unblocking carotid Reduce 5 year absolute risk of ipsilateral ischaemic stroke by 16% in patients with 70-99% stenosis Many risks associated
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What is thrombolysis?
``` Use of drugs to break up clot Considered if present within 4.5 hours Number of CI - High BP > 185/110 - Blood thinners - Bleeding - Major surgery - Unconfirmed stroke ```
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What is mechanical thrombectomy?
Use of catheter fed up into brain to aspirate clot or remove Indications - Proximal intracranial large vessel occlusion - Causing disabling neurological deficit - Procedure can begin within 5 hours of known onset
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What causes haemorrhagic strokes?
``` Cerebral amyloid angiopathy HTN Aneurysms AVMs Trauma Blood thinners ```
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What is the management of haemorrhagic strokes?
BP management 140/80 Reverse anticoag Neurosurg referral If develop hydrocephalus consider insertion of external ventricular drain
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What is frailty?
Distinct health state characterised by reduction in physiological reserve syndrome characterised by sudden onset of rapidly developing or focal or global neurological disturbance which lasts more than 24 hours or leads to death, with no apparent cause other than that of vascular origin Evidence linking frailty with mortality
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What are the different methods of scoring frailty?
Phenotype - Fried | Cumulative deficit - FI, CFS
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What is the fried criteria for frailty?
``` Description of a phenotype Clinical syndrome of > 3 of - Unintentional weight loss - Self-reported exhaustion - Weakness (grip strength) - Slow walking speed - Low physical activity If 2 then pre-frailty ```
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What does the Fried criteria predict?
Independently predictive over 3 years of incident falls, worsening mobility or ADL disability, hospitalisation, and death
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What is the clinical frailty scale?
Overall trend of increasing mortality with increasing frailty Not validated for measuring improvement in individuals after acute illness or for < 65 Practicality uses eg assessment for ITU admission suitablity
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What is the e-FI3?
Calculated by presence of absence of individual deficits as a proportion of 36 total possible deficits Mixture of co-morbidities, self reported symptoms and social factors Robust predictive validity for outcomes of 1, 3 ,and 5 year mortality, hospitalisation, and nursing home admission
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What is palliative care?
Treatment recognises irreversible nature of underlying disease process - holistic approach, symptoms control Disparity of access to palliative care for frail patients Benefit of palliative care is avoid futile treatment
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What is end of life care?
``` Last 12 months Disease relentless Frailty predictor of mortality Unpredictable Irreversible frailty/decline should prompt discussion re end of life ```
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What could advance care planning include?
``` Legal aspects Preferred place of care Treatment options acceptable to patient and suitable for patient DNAR Specific plan for complex scenarios ```
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What are the advantages of advanced care planning?
Open ended Personalised care - planning/stating preferences Avoids futile disease orientated treatment Patient-centred goals Improves co-ordination of care
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What is the role of a registered dietician?
Only qualified health professional that assesses, diagnoses and treats dietary and nutritional problems Works closely with MDT and covers a range of settings Therapeutic diets Improving nutrition Diagnosing nutritional problems Advising on feeding routes Advising on refeeding syndrome management Creon adjustments
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How common is malnutrition?
35% patients admitted to hospital at risk of malnutrition 70% patients weigh less on hospital discharge Affects over 3 million people in UK Cost 19.6 billion per year
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What are the causes of malnutrition?
Decreased nutrient intake (starvation) Increased nutrient requirements (sepsis or injury) Inability to utilise nutrients ingested (malabsorption) Or combination
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What are the consequences of malnutrition?
``` Weakened immune system Muscle wasting - increased falls, chest infection, decreased mobility/inactivity Impaired wound healing Micronutrient deficiencies Poorer prognosis Reduced QOL Increased length of stay Increased complications More re-admission Greater healthcare needs in community ```
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What is MUST?
Malnutrition universal screening tool Scores based on BMI, history of weight loss, acute disease effect Allows for development of care plan and monitoring BMI % unplanned weight loss Acute disease effect and score - acutely ill and has been or likely to be no nutritional intake for > 5 days If score 2 or more - high risk so treatF
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How do you treat malnutrition?
Food first Oral nutritional supplements Enternal/parenteral nutrition
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What oral nutritional supplements are used?
Liquid/powder/semi solid Macro/micronutrients Milkshakes, juice, soup, semi solid, high energy powders, high protein, low volume/high concentration Mainly sweet
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What is the IDDSI?
International dysphasia diet standardisation initiative SLT recommended Dysphasia - ensure feeding is in line with IDDSI Need different textures for different abilities to swallow or can lead to asphyxiation
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What is enteral nutriton?
Direct feeding into gut such as stomach/duodenum/jejunum Preserves gut mucosa and integrity Inexpensive compared to parenteral nutrition
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What are the disadvantages of enteral nutrition?
Tolerance levels eg nausea, satiety, bowel function Tube can be uncomfortable QoL, personal appearance
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What are the routes of enteral feeding?
NG - feeds into stomach, inserted at ward level, for short term use < 30 days, gold standard check pH aspirate, second line confirmation x-ray NJ - feeds into jejunum, short term use < 60 days, radiologically guided, can only check position with x-ray
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What are long term forms of enteral feeding and what are the indications for each?
PEG - dysphasia, CF, oral intake inadequate and likely to be long term Post pyloric/PEJ/surgical JEJ - delayed gastric emptying, upper GI/pancreatic surgery, high risk of aspiration, severe acute pancreatitis
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What is parenteral nutriton?
Feeding IV when gut is inaccessible or unable to absorb sufficient nutrition to sustain nutritional status
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What are the indications for parenteral nutrition?
Inadequate absorption GI fistula Bowel obstruction Prolonged bowel rest Severe malnutriton, significant weight loss and/or hypoproteinaemia when enteral therapy not possible Other disease states or conditions in which oral or enteral feeding is not an option
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What are the methods of giving parenteral nutrition?
PICC line or central line
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What are the advantages of parenteral nutrition?
Helpful to meet nutritional requirements and promote recovery if used appropriately Easily tolerated
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What are the disadvantages of parenteral nutrition?
More costly than enteral Risk of infection More invasive procedures Gut atrophy
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What is refeeding syndrome?
Group of clinical symptoms/signs that can occur in malnourished/starved patient when reintroducing nutrition Shift in use of energy stores from fat metabolism to carbohydrate metabolism Initiates insulin increase and cellular uptake of potassium, phosphate, and magnesium Shifts in fluid and electrolytes
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What are the results of refeeding syndrome?
Fluid retention Cardiac arrhythmias Respiratory insufficiency Death
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What is the treatment of refeeding syndrome?
IV pabrinex or thiamine + vit B co-strong to feeding and for first 10 days STH refeeding syndrome guidelines Slow reintroduction of nutrition Daily monitoring of refeeding bloods including U&Es, PO4, Mg and correct as necessary
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What are the differences between dementia and delirium?
Delirium has a sudden and severe onset, it is a brief episode, reversible, fluctuating consciousness, disorganised conversation, altered sleep-wake cycle Dementia is irreversible, increasing loss of cognition and brain function, alert, engages well, altered sleep wake cycle
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What are the symptoms of delirium?
``` Mood changes Changes in speech Sleep changes Disorientation and confusion Visual hallucinations (hyper) Physical issues ```
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What are the symptoms of dementia?
``` Memory loss Difficulty with ADLs Changes in mood Changes in ability to problem solve Increasing difficulty focussing or paying attention Changes to personality ```
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What is the relationship between delirium and dementia?
Interrelationship People with dementia more likely to develop delirium and people with multiple episodes of delirium are more likely to develop dementia
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What are the different types of dementia?
Alzheimer's disease Vascular dementia eg stroke (step-wise decline) Parkinson's disease Dementia with lewy body (Parkinsonism features) Frontotemporal dementia (disinhibition, progressive aphasia) Severe head injury
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How do you assess mental state?
``` History - Collateral - Onset - DHx, FHx - Effect on ADLs - CVS/previous delirium/TIA/stroke - Symptoms - SHx - smoking/alcohol General examination - Chest, HS, ect - Parkinsonism features MMSE AMT ```
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What investigations should you do in a confusion screen?
``` FBC U&E LFT Ca CRP ```
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What investigations should you do in dementia screen?
``` TSH B12 Folate FBC LFT U&E ESR/CRP Syphillis serology Glucose ```
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What should you do for someone under 50 with dementia symptoms?
Syphilis serology | HIV screen
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How is dementia managed?
Medications - Acetylcholinesterase inhibitors eg rivastigmine or donepezil - Mmeantine for severe dementia 12/less on MMSE Cognitive stimulation therapy Cognitive rehabilitation Reminiscence and life story work
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How does geriatric medicine differ from medicine for younger people?
More co-morbidities leading to polypharmacy Social issues so complex discharges Different atypical presentations Difficult to take histories - confusion, contralateral histories Ethical issues - high degree of mortality Slower response to treatment Non-specific signs and symptoms - longer admission, MDT involvement Silent issues - MI, PUD
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What are the 6I's of geriatric giants?
``` Instability (falls) Infirmity (confusion) Incontinence Immobility Inanition (frailty) Iatrogenic (polypharmacy) ```
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How is activity of daily living assessed?
Review with occupational therapists | Barthel index
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What does the Barthel index assess?
``` Feeding Bathing Grooming Dressing Bowels Toilet use Transfers Mobility Stairs ```
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What is polypharamacy?
Regular use of at least 5 medications
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Why is polypharmacy more likely to occur in older people?
Need to treat various disease states that develop with age More likely to have multiple conditions that need treating or conditions that require multiple medications to treat Drs often over prescribe
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What is the affect of aging on pharmacokinetics?
With age, increased body fat, and total body water decreased. Increased fat increased volume of distribution of highly lipophilic drugs Increased water decreases volume of distribution of highly hydrophilic drugs Hepatic metabolism of many drugs through cytochrome P-450 enzyme decreases with age - first pass metabolism decreased Decreased renal elimination of drugs Decreased albumin so less drug bound to it - less distribution Absorption is not affected
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What is the effect of aging on pharmacodynamics?
Effects of similar drug concentrations at the site of action may be greater or smaller than those in younger people Due to changes in drug-receptor interaction, in post-receptor events, or in adaptive homeostatic responses and among frail elderly often due to pathological changes in organs Response depends on specific drugs eg increased anti-cholinergic drug effects and hypoglycaemic drugs Most drugs have increased effect
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What are the complications of polypharmacy?
Increased risk of adverse drug events Increased risk of drug interactions Increased risk of medication non-adherence Reduced function capacity Multiple geriatric syndromes - cognitive impairment, falls, incontinence Increased healthcare costs
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How can polypharmacy be avoided?
Reviewing doses Elimination duplicate medications Assessing for drug-drug interactions Removing medications that aren't required
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Why should you stop NSAIDs in the elderly asap?
Worsen kidney function Increased risk of GI bleeding Increased risk of CVS events
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When should you stop clopidogrel after an MI?
12 months
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What should you prescribe after an MI?
Aspirin 300mg | Clopidogrel in adults over 76 - 75mg