GERD, Ulcers, Inflammatory Bowel Disease

Question 1

Symptoms of GERD Ulcers IBS Crohn’s Ulcerative colitis

Answer 1

GERD- substernal burning, pain radiating to throat
Ulcers- Epigastric pain
IBS- GI upset
Crohn’s and Ulcerative colitis- abd pain and diarr

Question 2

GERD risk factors

Answer 2

High fat meal, carbonated drinks, pregnancy, obesity and increase age

Question 3

GERD mild to severe txs

Answer 3

mild: antacids. alginates and non RX H2RA
severe: DOC PPI 2-4wks
* goal is to raise pH4

Question 4

DOC for food induced GERD

Answer 4

H2RA

Question 5

Antacids Al Ca Mg Na SEs

Answer 5

Al- constipation, hypoK
Ca cons, hyperCa-milk alkali syndrome, rebound hyperacidity
Mg- diarr, hyperMg
Na SEs

Question 6

DIs with antacids

Answer 6

Quinolones, Tetracycline, Digoxin

*separate dosing by 2h

Question 7

DIs of Ranitidine, decreases clearances of which drugs?

Answer 7

Theophylline, Phenytoin, Warfarin, Cimetidine; CYP450 inhibitors

Question 8

Omeprazole decreases metabolism of which drugs?

Answer 8

warfarin, Diazepam, Phenytoin, Clopidogrel

Question 9

All of the following are examples of gastric acid stimulators, EXCEPT and explain:

a) Gastrin
b) Acetylcholine
c) Somatotropin
d) G-Cell
e) None of the above

Answer 9

Somatotropin is a hormone growth with no effect on gastric acid secretion.

Question 10

Examples of the used of Karaya gum in ostomy patients may include:

Answer 10

Protect skin from stomach effluent. As skin adhesives and protective skin barriers in the fitting and care of ostomy, colostomy appliances and in other conditions involving an artificial stoma