GERD in Pregnancy

Question 1

1. Decrease LES tone due to ( )
2. Gastrin secretion
3. Above changes start at 15 weeks but stable until active labor.
4. Best choice of medication for GERD before emergency C/S
5. Onset of medications
   a. Sodium citrate 2. H2 blocker 3. Metclopramide

Answer 1

1. Progesterone and upward displacement of stomach
2. Increase (From placenta) > Decrease pH and increase volume
3. Sodium citrate
4. Sodium citrate (quick action and last 60min)
   H2 blocker and Proton pump inhibitor (takes 30 minutes)
   Metoclopramide (takes 15 min)