GERD Flashcards
Contraindication and what client should used H2 receptor antagonist cautiously?
Contraindicated: Hypersensitivity
Use cautiously: Impaired renal and hepatic function
Action and indication of H2 Receptor Antagonist
-Suppresses gastric acid secretion
-Alleviate Heartburn sx
-Promote healing of GERD
Route of Cimetidine (Tagamet) and Ranitidine (Zantac)
PO, IV and IM
What H2 Receptor antagonist should NOT be taken with food?
Cimetidine (Tagamet)
Rationale: it can delay the drug absorption
What is the effect of antacids while taking Cimetidine (Tagamet) ?
-Taking antacid decrease absorption of oral Cimetidine (Tagamet)
-when taking both Cimetidine (Tagamet) and antacid, at least 1 HOUR apart
What are the possible s/e of Cimetidine (Tagamet) ?
M- mental confusion
A - agitation
P - psychosis
D -depression
A -anxiety
D- disorientation
When and Why was Cimetidine (Tagamet) dosage is reduced in pt with GERD?
-if client have impaired renal fx (causes nephrotoxicity)
-When drug is administered with Warfarin Na, Phenytoin, Theophylline and Lidocaine ( to prevent drug interaction)
Taking Ranitidine is not affected by food?
T or F
True
What H2 receptor antagonist doesn’t need to be administered with food?
Famotidine (Pepcid) and Nizatidine (Acid)
5 overall consideration in H2 Receptor Antagonist:
- If prescribed OD, take drug at bedtime
- Take the drug 1 hour before and after taking ANTACID
- Avoid cigarette smoking, alcohol and NSAIDS
- Long term use: M-drug can lead to gynecomastia and impotence and F- lead to breast tenderness
- A/E:
Diarrhea, Rashes and bruises, Confusion, Fatigue and Malaise
At least 5 PPI drugs?
P- Pantoprazole (Protonix)
R- Rabeprazole ( Aciphex)
O- Omeprazole ( Prilosec)
L- Lansoprazole (Prevacid)
E- Esomeprazole ( Nexium)
Common S/E of PPI:
H- headache
A- abdominal pain
N- nausea
D- diarrhea
Nursing responsibility on PPI:
- If prescribed TID, instruct to take before breakfast and at bedtime; but if OD, take it at bedtime
- Monitor the liver function test (AST, ALT, Bilirubin) since its nephrotoxic
3.Avoid cigarette smoking, alcohol, aspirin and NSAIDs to promote healing
4.Do not chew the tablet to prevent to reduce the drug potency - Report black tarry stool (GI bleeding), diarrhea and abdominal pain
What are the extrapyramidal effects of Metoclopramide?
-Dysarthria -Twitching movements
-Dysphagia -Weakness of A and L
-Loss of balance -Tardive Dyskinesia
-Gait disturbances
Nsg. Responsibility of Metoclopramide?
- TID, 30 mins before breakfast and at bedtime
- by direct IVP over 1-2 mins or
Slow infusion over 15-30 mins - Avoid alcohol or CNS depressants