Gentomycin Flashcards

2
Q

What is it effective against

A

Enterobacter, E. coli, Klebsiella, Citrobacter, Pseudomonas, and Serratia.

some gram-positive bacteria, including some strains of MRSA.

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3
Q

What are the administration alerts

A
  1. Use only IM and IV solutions that are clear and colorless/slightly yellow.
  2. Discard discolored solutions or those with particulate matter.
  3. Withhold the drug if peak serum levels exceed 5-10 mcg/mL.
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4
Q

What are the adverse effects ?

A

Neurotoxicity, nephrotoxicity, neuromuscular blockade and paralysis

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5
Q

What are the early signs of neurotoxicity

A

Ototoxicity, tinnitus, vertigo, persistent headaches.

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6
Q

What are the other neurotoxicity signs

A

Paresthesias, muscle twitching, seizures.

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7
Q

What are the signs of nephrotoxicty

A

Oliguria, proteinuria, elevated BUN and creatinine levels.

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8
Q

When is gentomycin used

A

serious urinary, respiratory, nervous, or GI infections when less toxic antibiotics are contraindicated

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