gentamicin

Question 1

what is the classification of gentamicin?

Answer 1

aminoglycosides

Question 2

what are gentamicin used for

Answer 2

treating severe infections

Question 3

what are the C/I and precautions for gentamicin

Answer 3

hypersensitivity, pregnancy & lactation

Question 4

why is gentamicin general use limited

Answer 4

because of the potential for serious adverse effects

Question 5

what are the adverse effects of gentamicin

Answer 5

neurotoxicity, nephrotoxicity, ototoxicity & neuromuscular blockade (flaccidity)

Question 6

what are the drug interactions of gentamicin

Answer 6

acyclovir, amphotericin B (hepatitis), cephalothin, cisplatin, cyclosporine, loop diuretics, prostaglandin synthetase inhibitors, and vancomycin

Question 7

what are the patient and family education of gentamicin

Answer 7

• pt should not take drug if pregnant or breastfeeding

- teach pts how to identify, report, and manage s/s of allergic reaction and A/E

Question 8

what are the ongoing assessment and evaluation of gentamicin

Answer 8

coordinate the care of the patient to ensure that other potentially nephrotoxic or ototoxic drugs are not added to the treatment plan

Question 9

what are the most important drug core knowledge points needed to decrease or minimize A/E

Answer 9

• need peak/trough levels monitored throughout treatment because of narrow therapeutic margin
• monitor for signs of ototoxicity, inculding balance and gross hearing
• monitor for drug-induced diarrhea
• administer gentamicin and extended penicillins at least 2 hrs apart to ensure the efficacy of gentamicin
• ensure that culture/sensitivity testing have been done to ensure that gentamicin is the correct drug
• ensure adequate hydration
• gentamicin s/b given around the clock as ordered