acyclovir Flashcards
what is the classification of acyclovir?
purine nucleoside analogue (antiviral)
what is the trade name of acyclovir
Zovirax
what is the pharmacotherapeutics of acyclovir
treatment of herpesviruses
how is acyclovir administered
topical, oral or IV
what is the pharmacodynamics of acyclovir
undergoes phosphorylation. in an infected cell, it is converted by the viral enzyme thymidine kinase. once incorporated into the virus, it terminates DNA synthesis
what are the C/I and precautions of acyclovir
use caution in pts with ganciclovir hypersensitivity
what are the A/E of acyclovir
lightheadedness, anorexia, N/V, (abdominal pain & HA) not common
what are the D/I of acyclovir
valproic acid, hydantoins, theophyllines, and probenecid
what health status do you assess with acyclovir
assess medical Hx and function of kidneys
what are the life span and gender of acyclovir
pregnancy category c
what life styles, diets, and habits do you assess with acyclovir
can transmit disease to others
what environment do you assess with acyclovir
assess environment where drug will be given
what are the patient and family education of acyclovir
- advise pts to notify the prescriber if they are pregnant or breast-feeding
- emphasize that acyclovir does NOT prevent the transmission of infection to another person and does not cure the infection
what are the ongoing assessment and evaluation of acyclovir
monitor for the effectiveness of therapy, making sure to document new lesions and assess for possible secondary bacterial infections
