Genome Structure and Genomic Variations Flashcards
1
Q
What are intergenic regions?
A
composed of noncoding DNA that may direct the assembly of specific chromatin structures and can contribute to the regulation of nearby genes
2
Q
What are major components of intergenic regions?
A
tandem repeats and transposons
3
Q
What are single nucleotide polymorphisms?
A
SNPs; mutations
4
Q
What are copy number variations?
A
CNVs; structural variations in the genome that lead to different copies of DNA sections
5
Q
What are tandem repeats?
A
short sequences of nucleotides are repeated one right after the other
6
Q
What can unstable tandem repeats cause?
A
chromsome breaks and diseases
7
Q
What structures on the chromosome are generally rich in tandem repeats?
A
heterochromatin, centromeres, and telomeres
